Product image of Izzyring (Ethinylestradiol, Etonogestrel) supplied by GNH India

Izzyring

Active Ingredient:
Ethinylestradiol, Etonogestrel
Origin:
EU

Izzyring (Ethinylestradiol, Etonogestrel)

Ethinylestradiol and etonogestrel, the active ingredients in Izzyring, are a combined estrogen‑progestogen contraceptive presented as a vaginal ring for vaginal use. The hormone combination suppresses ovulation, thickens cervical mucus and alters the endometrial lining, thereby preventing pregnancy in women of reproductive age.

GNH India supplies Izzyring as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑controlled manufacturing and regulatory compliance across global markets. Our distribution network provides reliable logistics and documentation for import and customs clearance.

Manufacturer / TM Owner

Exeltis Germany Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Izzyring, a combined estrogen‑progestogen contraceptive, is used within the hormonal contraception pathway to prevent unintended pregnancy.
  • Contraception: provides reliable, reversible prevention of pregnancy by inhibiting ovulation and altering cervical mucus.
  • Family planning: offers a long‑acting, user‑controlled method for women seeking non‑daily hormonal birth control.
  • Menstrual regulation: may reduce menstrual flow and dysmenorrhea in some users as a secondary benefit.

How It Works

  • The ethinylestradiol component binds to estrogen receptors, while etonogestrel binds to progesterone receptors, together suppressing the hypothalamic‑pituitary‑ovarian axis. This inhibition reduces the secretion of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH), preventing follicular development and ovulation. Additionally, the progestogenic effect thickens cervical mucus and induces endometrial changes that are unfavorable for implantation. The combined hormonal action also stabilizes the endometrial lining, further reducing the chance of implantation during any accidental ovulation.

Side Effects

Izzyring may be associated with a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Vaginal irritation or discharge
  • Headache
  • Nausea
  • Breast tenderness

Serious or Rare Side Effects

  • Deep vein thrombosis or pulmonary embolism
  • Stroke or transient ischemic attack
  • Severe allergic reaction (anaphylaxis)

Precautions & Warnings

Before prescribing Izzyring, clinicians should evaluate several safety considerations to minimize risk.

  • Pregnancy: contraindicated in known or suspected pregnancy.
  • Smoking: avoid use in women over 35 who smoke due to increased thrombotic risk.
  • Cardiovascular history: assess for prior clotting disorders, stroke, or myocardial infarction.
  • Liver disease: use with caution in patients with active liver disease.
  • Drug interactions: review concomitant medications that may affect hormone levels.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct heat.

Avoid Interactions

Izzyring can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin, phenobarbital): may markedly reduce hormone concentrations and contraceptive efficacy.
  • Rifampin or rifabutin: strong inducer of hepatic enzymes, decreasing hormonal levels.
  • Antifungal azoles (e.g., ketoconazole, itraconazole): can increase hormone levels, raising risk of side effects.

Moderate Interactions (Monitor Closely)

  • Antibiotics such as tetracycline or metronidazole: may slightly lower contraceptive effectiveness.
  • St. John’s wort: herbal inducer that can reduce hormone levels.
  • Selective serotonin reuptake inhibitors (SSRIs): may increase risk of mood changes.

Frequently Asked Questions

Izzyring is a combined estrogen‑progestogen vaginal ring indicated for the prevention of unintended pregnancy. It provides a reversible, hormone‑based method of contraception that is user‑controlled and does not require daily dosing, making it suitable for women seeking long‑acting birth control.

Ethinylestradiol activates estrogen receptors while etonogestrel activates progesterone receptors. Together they suppress the hypothalamic‑pituitary‑ovarian axis, lowering luteinizing hormone and follicle‑stimulating hormone release, which prevents follicular development and ovulation. The progestogenic effect also thickens cervical mucus and modifies the endometrium, creating an environment hostile to fertilisation and implantation.

The prescribed regimen for Izzyring is determined by the treating clinician. Typically, a single vaginal ring is inserted and left in place for three consecutive weeks, followed by a ring‑free week to allow for withdrawal bleeding. Exact dosing and timing should follow the prescriber’s instructions and local product labeling.

Izzyring is contraindicated in women who are pregnant or suspect they might be pregnant. Because it delivers systemic hormones, it is generally not recommended for use while breastfeeding; the hormones may pass into breast milk and affect the infant. Women should discuss alternative contraception options with their healthcare provider if they are pregnant or nursing.

To order Izzyring, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

The primary alternative to Izzyring is the combined oral contraceptive pill. While both deliver ethinylestradiol and a progestogen, the vaginal ring provides continuous hormone release for three weeks with a single insertion, eliminating daily pill taking and reducing gastrointestinal absorption variability. Oral pills require daily adherence, whereas the ring offers a more convenient, low‑maintenance option for many users.

Izzyring should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect the product from excess moisture, direct sunlight and extreme heat. Do not freeze the ring. Keep it out of reach of children and handle it with clean, dry hands to maintain sterility before insertion.

Izzyring is a flexible vaginal ring that the user inserts into the vagina, where it remains in place for three weeks. After three weeks, the ring is removed and discarded, and a ring‑free week follows to allow withdrawal bleeding. A new ring is then inserted to start the next cycle. Insertion and removal can be performed by the user after appropriate instruction.

The most serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, cerebrovascular accidents (stroke or transient ischemic attack), myocardial infarction, and severe allergic reactions including anaphylaxis. These events are rare but require immediate medical attention. Women with a history of clotting disorders or cardiovascular disease should be evaluated carefully before use.

Izzyring is contraindicated in women who are pregnant, have known or suspected pregnancy, or are breastfeeding. It should also be avoided by women over 35 who smoke, those with a history of thromboembolic disease, stroke, myocardial infarction, uncontrolled hypertension, active liver disease, or known hypersensitivity to any component of the ring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.