Product image of Jaydess (Levonorgestrel) supplied by GNH India

Jaydess

Active Ingredient:
Levonorgestrel
Origin:
EU

Jaydess (Levonorgestrel)

Levonorgestrel, the active ingredient in Jaydess, is a progestin presented as a 13.5 mg intrauterine system for intrauterine use. It provides long‑acting hormonal contraception by releasing levonorgestrel directly within the uterine cavity, thereby preventing pregnancy in women of reproductive age.

GNH India supplies Jaydess as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each shipment. Customers receive comprehensive technical support and can rely on timely delivery across multiple continents.

Manufacturer / TM Owner

Bayer Austria Gmbh

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Indications & Clinical Uses

Levonorgestrel in Jaydess is a hormonal contraceptive used within the reproductive health pathway to prevent pregnancy.

  • Contraception (prevention of pregnancy): provides highly effective, reversible birth control for women of child‑bearing age.

How It Works

  • Levonorgestrel released from the intrauterine system thickens cervical mucus, reduces sperm motility and viability, and induces endometrial changes that inhibit implantation. The local hormone exposure may also suppress ovulation in some cycles, collectively preventing fertilisation and pregnancy.

Side Effects

Jaydess may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Irregular bleeding or spotting
  • Decreased menstrual bleeding or amenorrhea
  • Abdominal or pelvic discomfort
  • Breast tenderness

Serious or Rare Side Effects

  • Uterine perforation during insertion
  • Device expulsion or displacement
  • Pelvic inflammatory disease or severe infection

Precautions & Warnings

Before insertion, clinicians should evaluate patient suitability and counsel on potential risks.

  • Pregnancy screening: confirm the patient is not pregnant before placement
  • Contraindications: avoid in active pelvic infection, known uterine anomalies, or current pregnancy
  • Insertion by trained professional: ensure correct placement to minimise complications
  • Follow‑up visits: schedule post‑insertion checks to assess device position and patient response
  • Monitor for infection: advise patients to report fever, unusual discharge, or severe pain promptly
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct heat

Avoid Interactions

Levonorgestrel released from an intrauterine system has limited systemic exposure, yet some drug interactions may affect efficacy.

Major Interactions (Avoid)

  • Strong CYP3A4 enzyme inducers (e.g., phenytoin, carbamazepine, rifampicin): may reduce levonorgestrel levels and lower contraceptive effectiveness
  • Concurrent use of uterine‑acting agents that increase infection risk (e.g., intrauterine antibiotics): may heighten pelvic infection risk

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): may modestly increase systemic levonorgestrel exposure
  • HIV protease inhibitors: potential modest interaction, monitor for breakthrough bleeding
  • St. John's wort: may slightly reduce hormone levels, advise vigilance for reduced efficacy

Frequently Asked Questions

Jaydess is an intrauterine system that provides long‑acting hormonal contraception. It is indicated for the prevention of pregnancy in women of reproductive age and offers a reversible, highly effective birth‑control option that can remain in place for up to three years.

Levonorgestrel released from the device acts locally in the uterus. It thickens cervical mucus, impairs sperm motility, and creates endometrial changes that prevent implantation. In some cycles it may also suppress ovulation, together ensuring that fertilisation does not occur.

The dose of Jaydess is set by the prescribing clinician. The system contains 13.5 mg of levonorgestrel and releases approximately 20 µg per day, providing continuous contraceptive effect for up to three years after insertion.

Jaydess must not be used during an existing pregnancy; if pregnancy occurs, the device should be removed promptly. Limited data exist for breastfeeding, but the low systemic exposure generally poses minimal risk. Women should discuss individual circumstances with their healthcare provider.

To order Jaydess, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Jaydess and other levonorgestrel‑releasing IUSs such as Mirena share the same mechanism and high contraceptive efficacy. Jaydess contains a lower total hormone load (13.5 mg) and is approved for up to three years of use, whereas some alternatives contain higher doses and may be approved for five years, offering clinicians flexibility based on patient needs.

Jaydess should be stored at ambient temperature, below 25 °C, in its original sealed packaging. Protect the device from moisture, direct sunlight and extreme heat. Handling should be performed by trained healthcare professionals using aseptic technique during insertion.

Jaydess is inserted by a qualified healthcare professional into the uterine cavity through the cervical canal. The procedure is performed in a clinical setting using a sterile inserter. Once placed, the device remains effective without the need for daily user action.

Serious risks include uterine perforation during insertion, device expulsion or displacement, pelvic inflammatory disease, and the rare possibility of ectopic pregnancy if contraception fails. Prompt medical evaluation is essential if severe abdominal pain, abnormal bleeding or signs of infection develop.

Jaydess is contraindicated in women who are currently pregnant, have active pelvic infections, untreated cervical or uterine malignancies, unexplained vaginal bleeding, or known uterine anomalies that could impede device placement. Individuals with a history of severe allergic reaction to levonorgestrel should also avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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