What is Jaydess used for?

Jaydess

Active Ingredient:: Levonorgestrel
Origin:: EU

Jaydess (Levonorgestrel)

Levonorgestrel, the active ingredient in Jaydess, is a progestin presented as a 20 µg/day intrauterine system for intrauterine use. It prevents pregnancy and can be used to manage heavy menstrual bleeding.

GNH India supplies Jaydess as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Sa Nv

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Indications & Clinical Uses

Jaydess is a hormonal intrauterine system that acts on the reproductive endocrine pathway to provide contraception and control menstrual bleeding.

Contraception: offers highly effective, reversible birth control for women of reproductive age.
Heavy menstrual bleeding: reduces menstrual blood loss and improves quality of life.
Menstrual cycle regulation: helps achieve more predictable bleeding patterns and may lessen dysmenorrhea.

How It Works

Jaydess continuously releases levonorgestrel locally within the uterine cavity. Levonorgestrel binds to progesterone receptors, suppressing ovulation, thickening cervical mucus to impede sperm penetration, and inducing endometrial atrophy, which together prevent implantation and reduce menstrual bleeding.

Side Effects

Jaydess may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

Irregular bleeding or spotting.
Amenorrhea (absence of periods).
Pelvic or abdominal cramping.
Hormonal acne.

Serious or Rare Side Effects

Uterine perforation during insertion.
Expulsion of the intrauterine system.
Pelvic infection (e.g., PID).
Ectopic pregnancy if contraception fails.
Allergic reaction to device components.

Precautions & Warnings

Before insertion and during use, certain precautions should be observed to ensure safety.

Pregnancy screening: confirm the patient is not pregnant prior to insertion.
Contraindications: avoid use in active pelvic infection, unexplained vaginal bleeding, or known hypersensitivity to levonorgestrel.
Position verification: check IUS placement with ultrasound after insertion.
Device removal: ensure removal before the approved duration expires.
Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levonorgestrel released from Jaydess can be affected by other medicines that alter hormone metabolism.

Major Interactions (Avoid)

Rifampin and other strong enzyme inducers: may reduce levonorgestrel efficacy.
Carbamazepine: can lower systemic hormone levels.
Efavirenz (antiretroviral): may compromise contraceptive effectiveness.

Moderate Interactions (Monitor Closely)

Ketoconazole and other azole antifungals: may increase hormone exposure.
St. John’s wort: moderate enzyme induction may reduce effectiveness.
Certain antibiotics (e.g., griseofulvin): may modestly affect hormone levels.

Frequently Asked Questions

Jaydess is an intrauterine system that delivers levonorgestrel to provide highly effective reversible contraception and to reduce heavy menstrual bleeding in women of reproductive age.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 15 Aug 2026

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