Product image of Jaydess (Levonorgestrel) supplied by GNH India

Jaydess

Active Ingredient:
Levonorgestrel
Origin:
EU

Jaydess (Levonorgestrel)

Levonorgestrel, the active ingredient in Jaydess, is a progestogen (hormonal contraceptive) presented as an intrauterine system for intrauterine use. It provides long‑term reversible contraception by releasing levonorgestrel locally to prevent pregnancy in women of reproductive age and is approved in the European Union for up to three years of continuous use.

GNH India supplies Jaydess as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution.

Manufacturer / TM Owner

Bayer Oy

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Jaydess, a levonorgestrel intrauterine system, is used within the contraceptive pathway to prevent unintended pregnancy.

  • Contraception: provides up to three years of highly effective pregnancy prevention.
  • Hormonal birth control: delivers a steady low dose of levonorgestrel directly to the uterine lining.
  • Intrauterine device therapy: offers a reversible, non‑daily method for women seeking long‑term contraception.

How It Works

  • Levonorgestrel released from the intrauterine system acts locally on the endometrium, suppressing its growth and thickening cervical mucus, which together impede sperm penetration and may inhibit ovulation, thereby preventing implantation and pregnancy.

Side Effects

Levonorgestrel released from the intrauterine system can be associated with a range of adverse reactions.

Common Side Effects

  • Irregular bleeding or spotting, especially in the first months.
  • Amenorrhea (absence of menstrual bleeding) after continued use.
  • Pelvic or abdominal discomfort.
  • Breast tenderness or mild headache.
  • Acne or oily skin changes.

Serious or Rare Side Effects

  • Uterine perforation during insertion.
  • Expulsion of the device.
  • Pelvic inflammatory disease or infection.
  • Ectopic pregnancy if contraception fails.

Precautions & Warnings

Before insertion and during use, several precautions should be observed to ensure safety and effectiveness.

  • Confirm non‑pregnancy: verify the patient is not pregnant prior to insertion.
  • Evaluate uterine anatomy: assess for fibroids, septa, or other abnormalities.
  • Treat active infections: resolve pelvic or cervical infections before device placement.
  • Counsel on bleeding changes: inform patients about possible irregular bleeding patterns.
  • Review contraindications: avoid use in women with known or suspected malignancy, liver disease, or unexplained vaginal bleeding.
  • Store at ambient temperature: keep the device in its original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Levonorgestrel IUS may interact with other medicines that affect hormone metabolism or uterine environment.

Major Interactions (Avoid)

  • Strong enzyme inducers such as rifampicin, carbamazepine, or phenytoin, which may reduce levonorgestrel efficacy.
  • Antiretroviral drugs like efavirenz that accelerate hormonal clearance.
  • St John’s wort, a herbal inducer of CYP enzymes, potentially decreasing contraceptive effect.

Moderate Interactions (Monitor Closely)

  • Certain antifungal agents (e.g., ketoconazole) that can alter hormone levels.
  • Antibiotics such as tetracycline that may affect gut flora and hormone reabsorption.
  • Anticonvulsants with moderate inducing activity (e.g., phenobarbital) requiring monitoring.

Frequently Asked Questions

Jaydess is a levonorgestrel intrauterine system indicated for the prevention of pregnancy. It provides a highly effective, reversible contraceptive method that can protect against unintended pregnancy for up to three years after insertion.

Levonorgestrel released from the device acts locally on the uterine lining, suppressing endometrial growth and thickening cervical mucus. These actions together hinder sperm movement, may prevent ovulation, and create an environment that is unfavorable for implantation, thereby reducing the chance of pregnancy.

The dose and duration of Jaydess are predetermined by the manufacturer and selected by the prescribing clinician based on the patient’s contraceptive needs. The prescriber decides whether the device is appropriate; patients should not alter the device or its dosing regimen.

Jaydess is not intended for use during an existing pregnancy. If pregnancy occurs while the device is in place, it should be removed promptly. Limited data suggest it is compatible with breastfeeding, but clinicians usually assess individual risk‑benefit before continuation.

To order Jaydess, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Jaydess offers continuous low‑dose levonorgestrel release, providing up to three years of protection without daily dosing, unlike oral contraceptives. Compared with copper IUDs, it may cause less menstrual bleeding but can lead to hormonal side effects. Its efficacy is comparable to other hormonal IUS devices such as Mirena, while offering a slightly shorter approved duration.

Jaydess should be stored at ambient temperature, below 25 °C, in its original sealed packaging. It must be protected from moisture, direct sunlight, and extreme temperatures. Healthcare providers should handle the device with clean, dry gloves during insertion to maintain sterility.

Jaydess is inserted by a trained healthcare professional into the uterine cavity using a specialized inserter. The procedure is performed in a clinical setting after confirming the patient is not pregnant and that the uterine cavity is suitable. Once placed, the device remains in situ for up to three years unless removal is required.

Serious risks include uterine perforation during insertion, device expulsion, pelvic inflammatory disease or infection, and the rare possibility of ectopic pregnancy if contraceptive failure occurs. Patients should be instructed to seek immediate medical attention for severe abdominal pain, abnormal bleeding, or signs of infection.

Jaydess is contraindicated in women who are currently pregnant, have unexplained vaginal bleeding, known or suspected uterine or breast cancer, active pelvic infection, severe liver disease, or anatomical uterine abnormalities that would impede proper placement. Individuals with a history of thromboembolic disorders should also discuss alternatives with their clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.