Product image of Jaydess (Levonorgestrel) supplied by GNH India

Jaydess

Active Ingredient:
Levonorgestrel
Origin:
EU

Jaydess (Levonorgestrel)

Levonorgestrel, the active ingredient in Jaydess, is a progestin presented as a 13.5 mg intrauterine system for intrauterine use. It releases a low dose of hormone locally within the uterus to provide reliable, long‑term reversible contraception and prevent pregnancy in women of reproductive age seeking a highly effective birth‑control method.

GNH India supplies Jaydess as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable logistics for global markets.

Manufacturer / TM Owner

Bayer Healthcare

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Indications & Clinical Uses

  • Jaydess, a levonorgestrel intrauterine system, is used within the hormonal contraceptive pathway to prevent unintended pregnancy.
  • Contraception: provides long‑term, reversible birth control for women of reproductive age, reducing the risk of unintended pregnancy for up to three years and often resulting in lighter menstrual bleeding.
  • Post‑abortion contraception: offers immediate, reliable contraception after surgical or medical abortion.
  • Post‑partum contraception: can be inserted after delivery to deliver prompt contraceptive protection during the postpartum period.

How It Works

  • Levonorgestrel released from the intrauterine system binds to progesterone receptors in the endometrium, suppressing ovulation, thickening cervical mucus, and inducing endometrial changes that inhibit implantation, thereby providing effective contraceptive action.

Side Effects

Jaydess may be associated with a range of adverse reactions.

Common Side Effects

  • Irregular vaginal bleeding or spotting
  • Amenorrhea (absence of periods)
  • Pelvic or abdominal cramping
  • Breast tenderness
  • Headache
  • Mood changes

Serious or Rare Side Effects

  • Uterine perforation during insertion
  • Pelvic inflammatory infection
  • IUS expulsion or displacement
  • Ectopic pregnancy if contraception fails
  • Allergic reaction (rash, swelling, anaphylaxis)
  • Ovarian cyst formation

Precautions & Warnings

  • Before insertion and during use, certain precautions should be observed.
  • Pregnancy screening: confirm the patient is not pregnant before placement.
  • Uterine assessment: evaluate cavity size and shape to ensure suitability.
  • Infection risk: avoid insertion in the presence of active pelvic infection.
  • Bleeding counseling: inform about possible changes in menstrual patterns.
  • Follow‑up: schedule post‑insertion checks to confirm correct positioning.
  • Store at room temperature: keep the device in its original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levonorgestrel IUS has limited systemic drug interactions, but some agents may affect contraceptive efficacy.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin)
  • Rifampicin or other strong CYP450 inducers
  • Certain antiretroviral therapies that reduce hormone levels

Moderate Interactions (Monitor Closely)

  • Antibiotics such as griseofulvin (potentially reduced effectiveness)
  • Herbal supplements containing St. John’s wort
  • Hormonal therapies that may increase side‑effect risk
  • Medications that alter uterine environment (e.g., uterotonics)

Frequently Asked Questions

Jaydess is a levonorgestrel intrauterine system indicated for long‑term hormonal contraception. It provides reversible birth control for women of reproductive age, preventing pregnancy for up to three years after insertion.

Levonorgestrel released from the IUS binds to progesterone receptors in the uterus, suppressing ovulation, thickening cervical mucus, and altering the endometrium. These actions together prevent fertilisation and implantation, delivering effective contraception.

The dose of levonorgestrel in Jaydess is fixed at 13.5 mg within the intrauterine system. The prescribing clinician determines the appropriate use and insertion timing; no patient‑adjusted dosing is required.

Jaydess must not be used in women who are pregnant. It is intended for insertion in non‑pregnant patients. Breastfeeding women may use the device, but they should discuss any concerns with their healthcare provider.

To order Jaydess, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with oral progestin pills, Jaydess offers continuous low‑dose hormone delivery directly to the uterus, eliminating daily adherence requirements and often resulting in fewer systemic side effects. It provides longer protection than most short‑acting methods but requires a clinical procedure for insertion and removal.

Jaydess should be stored at room temperature, below 25 °C, in its original sealed packaging. Protect the device from moisture and direct sunlight until it is inserted by a qualified healthcare professional.

Jaydess is inserted into the uterine cavity by a trained clinician using a specialized applicator. The procedure is performed in a clinical setting under aseptic conditions, and the device remains in place for up to three years before removal or replacement.

Serious risks include uterine perforation during insertion, pelvic inflammatory infection, device expulsion or displacement, and the rare possibility of ectopic pregnancy if contraceptive failure occurs. Prompt medical attention is required if severe abdominal pain, abnormal bleeding, or signs of infection develop.

Jaydess is contraindicated in women who are currently pregnant, have active pelvic infection, unexplained vaginal bleeding, known or suspected uterine anomalies, or a history of uterine perforation. Patients with certain cancers or severe liver disease should also avoid this device.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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