Product image of Jaydess (Levonorgestrel) supplied by GNH India

Jaydess

Active Ingredient:
Levonorgestrel
Origin:
EU

Jaydess (Levonorgestrel)

Levonorgestrel, the active ingredient in Jaydess, is a progestin presented as a 13.5 mg intrauterine system for intrauterine use. It provides long‑acting contraception by preventing ovulation and creating a uterine environment that is unfavorable for fertilization and implantation in women of reproductive age.

GNH India supplies Jaydess as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each shipment. Customers receive technical support and training for proper insertion and follow‑up care.

Manufacturer / TM Owner

Jenapharm Gmbh & Co Kg

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Jaydess, a levonorgestrel intrauterine system, is used within the contraceptive pathway to prevent pregnancy.
  • Contraception (general): prevents pregnancy for up to three years in women of reproductive age.
  • Post‑abortion contraception: provides reliable birth control immediately after a therapeutic abortion.
  • Post‑partum contraception: offers effective contraception following childbirth while allowing breastfeeding.

How It Works

  • Levonorgestrel is released locally from the intrauterine system, where it binds to progesterone receptors in the endometrium, cervical mucus, and hypothalamic‑pituitary axis. This suppresses ovulation, thickens cervical mucus to impede sperm passage, and induces endometrial changes that reduce the likelihood of implantation, thereby preventing pregnancy.

Side Effects

Jaydess may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Irregular vaginal bleeding or spotting
  • Amenorrhea (absence of periods)
  • Pelvic or cramping pain after insertion
  • Breast tenderness
  • Headache
  • Nausea

Serious or Rare Side Effects

  • Uterine perforation during insertion
  • Device expulsion or displacement
  • Pelvic inflammatory disease or infection
  • Ectopic pregnancy if contraception fails
  • Severe allergic reaction (anaphylaxis)

Precautions & Warnings

  • Before prescribing Jaydess, clinicians should evaluate several safety considerations.
  • Screen for pregnancy: confirm the patient is not pregnant prior to insertion.
  • Assess uterine anatomy: avoid use in patients with known uterine anomalies or fibroids that may impede placement.
  • Check for active infection: postpone insertion if pelvic infection is present.
  • Counsel on bleeding changes: inform patients that spotting or amenorrhea are common.
  • Avoid in known hypersensitivity: do not use if the patient has a documented allergy to levonorgestrel or device components.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levonorgestrel released from Jaydess can be affected by certain concomitant medicines.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may markedly reduce contraceptive efficacy.
  • Rifampin and other strong CYP3A4 inducers: can lower levonorgestrel levels and increase risk of unintended pregnancy.

Moderate Interactions (Monitor Closely)

  • Certain antibiotics (e.g., tetracycline): may slightly decrease hormone effectiveness.
  • Antiretroviral agents (e.g., efavirenz): may reduce levonorgestrel concentrations.
  • Herbal supplements such as St. John’s wort: can increase hormone metabolism and diminish contraceptive reliability.

Frequently Asked Questions

Jaydess is a levonorgestrel‑containing intrauterine system designed to provide long‑acting reversible contraception. It is inserted into the uterus and releases a low dose of hormone over up to three years, preventing ovulation and creating conditions that are unfavorable for fertilization and implantation.

Levonorgestrel released from the device binds to progesterone receptors in the endometrium, cervical mucus, and the hypothalamic‑pituitary axis. This suppresses ovulation, thickens cervical mucus to block sperm entry, and induces endometrial changes that reduce the chance of implantation.

The dosage of Jaydess is fixed at 13.5 mg of levonorgestrel released continuously from the intrauterine system. The exact regimen, including insertion timing and follow‑up, is determined by the prescribing healthcare professional based on individual patient needs.

Jaydess is intended for use in women who are not pregnant. It must be inserted after confirming the absence of pregnancy. While it can be used by breastfeeding mothers, the hormone levels are low and generally considered compatible with lactation, but clinicians should assess each case individually.

To order Jaydess, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with oral progestin pills, Jaydess offers continuous hormone delivery without daily dosing, leading to higher typical‑use effectiveness and improved compliance. Unlike higher‑dose intrauterine systems such as Mirena, Jaydess contains a lower levonorgestrel amount (13.5 mg) and is approved for up to three years of use, making it suitable for women seeking a lower‑dose option.

Jaydess should be stored at room temperature, below 25 °C, in its original sealed packaging. It must be protected from moisture and direct sunlight. The device should be kept out of reach of children and handled only by trained healthcare professionals during insertion.

Jaydess is inserted by a qualified healthcare provider into the uterine cavity through the cervical canal using a specialized inserter. The procedure is performed in a clinical setting under aseptic conditions. Once placed, the device remains in situ for up to three years, after which it can be removed or replaced.

Serious risks, although rare, include uterine perforation during insertion, device expulsion or displacement, pelvic inflammatory disease, and ectopic pregnancy if contraceptive failure occurs. Patients should be instructed to seek immediate medical attention for severe abdominal pain, abnormal bleeding, or signs of infection.

Jaydess is contraindicated in women who are currently pregnant, have active pelvic infection, known or suspected uterine anomalies that could impede placement, or a documented hypersensitivity to levonorgestrel or any component of the device. It should also be avoided in patients with a history of breast cancer or severe liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.