Product image of Jellin-Neomycin (Neomycin Sulfate, Fluocinolone Acetonide) supplied by GNH India

Jellin-Neomycin

Active Ingredient:
Neomycin Sulfate, Fluocinolone Acetonide
Origin:
EU

Jellin-Neomycin (Neomycin Sulfate, Fluocinolone Acetonide)

Neomycin Sulfate and Fluocinolone Acetonide, the active ingredient in Jellin-Neomycin, is an antibiotic and corticosteroid presented as a topical formulation for skin use. It treats inflammatory and bacterial skin conditions such as dermatitis, eczema, and superficial infections in adults and children.

GNH India supplies Jellin‑Neomycin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teofarma S.R.L.

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Indications & Clinical Uses

  • Jellin‑Neomycin is a combined topical antibiotic and anti‑inflammatory used for a range of dermatologic conditions.
  • Dermatitis: reduces inflammation and bacterial colonisation, improving skin integrity.
  • Eczema: alleviates itching, redness and secondary infection risk.
  • Inflammatory skin conditions: suppresses cytokine production and relieves swelling.
  • Superficial bacterial skin infections: eradicates susceptible bacteria while controlling local inflammation.

How It Works

  • Neomycin sulfate binds to the bacterial 30S ribosomal subunit, inhibiting protein synthesis and leading to bacterial cell death. Fluocinolone acetonide acts as a glucocorticoid receptor agonist, modulating gene transcription to suppress pro‑inflammatory cytokines, reduce leukocyte migration, and diminish edema in the treated skin area.

Side Effects

Adverse reactions are generally limited to the application site, but systemic effects can occur rarely.

Common Side Effects

  • Mild burning or stinging sensation
  • Local itching or pruritus
  • Redness or erythema at the application site
  • Dryness or flaking of the skin
  • Slight peeling or scaling
  • Mild irritation with prolonged use

Serious or Rare Side Effects

  • Allergic contact dermatitis with vesiculation
  • Severe skin ulceration or necrosis
  • Systemic hypersensitivity reactions (e.g., urticaria, angioedema)
  • Secondary infection due to over‑suppression of local immunity
  • Adrenal axis suppression with extensive use
  • Rare ototoxicity if absorbed in large amounts

Precautions & Warnings

  • Before using Jellin‑Neomycin, consider the following safety measures.
  • Avoid use on broken skin: limit application to intact epidermis.
  • Do not apply to viral, fungal or herpetic lesions: risk of worsening infection.
  • Limit duration of treatment: prolonged use may increase risk of skin atrophy.
  • Use with caution in patients with known hypersensitivity to neomycin or corticosteroids.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Jellin‑Neomycin may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid)

  • Systemic aminoglycosides: additive ototoxicity or nephrotoxicity.
  • Concurrent topical corticosteroids: increased risk of systemic absorption and skin thinning.
  • Live vaccines applied near the site: possible local immune suppression.

Moderate Interactions (Monitor Closely)

  • Topical antifungal agents: may reduce antifungal efficacy.
  • Systemic immunosuppressants: heightened infection risk.
  • Skin care products containing alcohol or strong irritants: may exacerbate local irritation.

Frequently Asked Questions

Jellin‑Neomycin is indicated for the topical treatment of inflammatory skin disorders such as dermatitis and eczema, as well as for superficial bacterial skin infections. It combines an antibiotic with a corticosteroid to reduce both infection and inflammation at the site of application.

Neomycin sulfate binds to the bacterial 30S ribosomal subunit, blocking protein synthesis. This action stops bacterial growth and leads to cell death, helping to clear susceptible skin‑surface bacteria that may complicate inflammatory conditions.

The specific dosage and frequency are determined by the prescribing clinician based on the severity of the condition, patient age, and treatment area. Patients should follow the healthcare professional’s instructions and not alter the regimen without consultation.

Safety data for Jellin‑Neomycin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

Enquiries can be submitted through the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑agent topical antibiotics, Jellin‑Neomycin offers the added benefit of a corticosteroid, providing simultaneous anti‑inflammatory action. This can result in faster symptom relief for conditions where both infection and inflammation coexist, though the combination may increase the risk of steroid‑related side effects.

Store Jellin‑Neomycin at room temperature, ideally below 25 °C. Keep the tube or container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use.

The product is applied topically to the affected skin area in a thin layer, usually once or twice daily as directed by a healthcare professional. Hands should be washed before and after application, and the treated area should be gently cleaned and dried beforehand.

Serious risks include allergic contact dermatitis, severe skin ulceration, systemic hypersensitivity reactions, and rare adrenal suppression with extensive use. Patients should seek immediate medical attention if they experience widespread rash, swelling, breathing difficulty, or signs of infection worsening.

Individuals with a known hypersensitivity to neomycin, fluocinolone, other aminoglycoside antibiotics, or any component of the formulation should avoid using Jellin‑Neomycin. It is also contraindicated on extensive broken skin, viral or fungal lesions, and in patients where systemic corticosteroid exposure is undesirable.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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