Product image of Jelnu (Tamsulosin Hydrochloride, Dutasteride) supplied by GNH India

Jelnu

Active Ingredient:
Tamsulosin Hydrochloride, Dutasteride
Origin:
EU

Jelnu (Tamsulosin Hydrochloride, Dutasteride)

Tamsulosin Hydrochloride and Dutasteride, the active ingredients in Jelnu, are an alpha‑1 adrenergic antagonist and a 5‑alpha‑reductase inhibitor presented as an oral tablet formulation for oral use. They are indicated for the management of benign prostatic hyperplasia in adult men.

GNH India supplies Jelnu as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Customers benefit from reliable supply chains and responsive technical support throughout the ordering process.

Manufacturer / TM Owner

Glaxosmithkline S.P.A.

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Indications & Clinical Uses

Jelnu combines tamsulosin and dutasteride to address benign prostatic hyperplasia and related lower urinary tract symptoms.

  • Benign prostatic hyperplasia (BPH): Improves urinary flow and reduces urgency, frequency, and nocturia.
  • Prostatic enlargement: Decreases prostate volume over time, relieving urethral obstruction.
  • Lower urinary tract symptoms (LUTS) associated with BPH: Alleviates bladder outlet obstruction and enhances quality of life.

How It Works

  • Tamsulosin selectively blocks alpha‑1 adrenergic receptors in the prostate and bladder neck, reducing smooth‑muscle tone and facilitating urine passage. Dutasteride inhibits both type I and type II 5‑alpha‑reductase enzymes, lowering conversion of testosterone to dihydrotestosterone, which leads to a gradual reduction in prostate size and further improvement of urinary symptoms.

Side Effects

Jelnu may be associated with several adverse reactions, which are categorized by frequency.

Common Side Effects

  • Dizziness: Light‑headedness, especially after the first dose.
  • Abnormal ejaculation: Decreased volume or retrograde ejaculation.
  • Headache: Mild to moderate intensity.
  • Nasal congestion: Stuffy or runny nose.

Serious or Rare Side Effects

  • Priapism: Persistent, painful erection requiring immediate medical attention.
  • Severe hypotension: Marked drop in blood pressure leading to fainting.
  • Allergic reactions: Rash, itching, or swelling of the face and throat.

Precautions & Warnings

When prescribing Jelnu, clinicians should consider several safety measures to minimize risk.

  • Monitor blood pressure: Assess for orthostatic changes, particularly after initiation.
  • Assess PSA levels: Obtain baseline prostate‑specific antigen before therapy.
  • Avoid use in severe hepatic impairment: Dose adjustment may be necessary.
  • Caution in cataract surgery patients: Increased risk of intra‑operative floppy iris syndrome.
  • Store at ambient temperature: Keep in the original container, protect from moisture and light.

Avoid Interactions

Jelnu can interact with other medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Finasteride: Concurrent use may increase sexual side‑effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): May raise dutasteride plasma concentrations.
  • Other alpha‑blockers (e.g., doxazosin): Additive hypotensive effect.
  • Warfarin: Potential enhancement of anticoagulant activity.

Moderate Interactions (Monitor Closely)

  • Diuretics: May potentiate orthostatic hypotension.
  • Antihypertensives: Blood pressure should be regularly monitored.

Frequently Asked Questions

Jelnu is prescribed for the treatment of benign prostatic hyperplasia (BPH) in adult men. It combines two agents that relax prostate smooth muscle and reduce prostate size, helping to improve urinary flow and relieve symptoms such as urgency, frequency, and nocturia.

Tamsulosin Hydrochloride selectively blocks alpha‑1 adrenergic receptors located in the prostate and bladder neck. By inhibiting these receptors, it relaxes smooth‑muscle tone, which decreases resistance to urine flow and eases lower urinary tract symptoms associated with BPH.

The dosage of Jelnu is individualized by the prescribing clinician based on the patient’s condition, renal and hepatic function, and other medications. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Jelnu is intended for use in adult men with BPH and is not recommended for women who are pregnant or breastfeeding. There is insufficient data on safety in these populations, and the risk–benefit profile has not been established.

To request Jelnu, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Jelnu combines an alpha‑1 blocker (tamsulosin) with a 5‑alpha‑reductase inhibitor (dutasteride), offering both rapid symptom relief and long‑term reduction of prostate volume. Single‑agent therapies provide only one of these effects, so Jelnu may achieve faster improvement while also shrinking the gland over time.

Jelnu should be stored at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct light, and ensure the container is tightly closed to maintain product stability.

Jelnu is taken orally, usually once daily with a glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their healthcare professional.

Serious risks include severe hypotension, priapism, and allergic reactions such as rash, swelling, or difficulty breathing. Patients should seek immediate medical attention if they experience any of these symptoms while using Jelnu.

Jelnu is contraindicated in patients with known hypersensitivity to tamsulosin, dutasteride, or any excipients, as well as in men with severe hepatic impairment. Caution is also advised for individuals undergoing cataract surgery due to the risk of intra‑operative floppy iris syndrome.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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