Jokath (Timolol, Travoprost)

Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors, while travoprost increases uveoscleral outflow by activating prostaglandin F2α receptors. The dual mechanism provides a greater overall reduction in intra‑ocular pressure than either agent alone.

The dosing schedule for Jokath is determined by the prescribing ophthalmologist based on the patient’s intra‑ocular pressure, disease severity, and response to therapy. Patients should follow the specific instructions provided by their healthcare professional.

Jokath should be used during pregnancy or lactation only if the potential benefit outweighs any possible risk to the fetus or infant. Clinicians typically evaluate the necessity of treatment and consider alternative options when possible.

To request Jokath, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with single‑agent drops, Jokath combines a beta‑blocker and a prostaglandin analog, offering a synergistic IOP‑lowering effect that may reduce the need for multiple separate medications. This can improve adherence and simplify treatment regimens.

Jokath should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging until use to maintain stability and potency.

Jokath is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, instill the prescribed number of drops, and close the eye gently without rubbing. Contact lenses should be removed before administration and re‑inserted after a suitable interval.

Serious risks include significant bradycardia, severe allergic reactions such as anaphylaxis, worsening of asthma or COPD, and rare ocular complications like uveitis or iris pigmentation changes. Patients should seek immediate medical attention if they experience these symptoms.

Jokath is contraindicated in patients with known hypersensitivity to timolol, travoprost, or any excipients, as well as those with severe sinus bradycardia, uncontrolled asthma, or acute pulmonary disease. It should also be avoided in individuals with a history of severe ocular inflammation.