Product image of Jolastic (Chlorphenamine Maleate, Paracetamol) supplied by GNH India

Jolastic

Active Ingredient:
Chlorphenamine Maleate, Paracetamol
Origin:
EU

Jolastic (Chlorphenamine Maleate, Paracetamol)

Chlorphenamine Maleate and Paracetamol, the active ingredients in Jolastic, is a first‑generation antihistamine and analgesic/antipyretic presented as an oral tablet for oral use. It relieves nasal congestion, sneezing, itching, fever and mild to moderate pain in adults and children.
GNH India supplies Jolastic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Abiogen Pharma S.P.A.

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Indications & Clinical Uses

Jolastic combines chlorphenamine maleate and paracetamol to address allergic and flu‑related symptom groups.

  • Allergic rhinitis: reduces nasal congestion, sneezing and itching associated with seasonal allergies.
  • Common cold: alleviates headache, sore throat, fever and general discomfort.
  • Mild to moderate pain: provides analgesia for headache, musculoskeletal aches and sore throat.

How It Works

  • Chlorphenamine maleate blocks H1‑histamine receptors, preventing the actions of histamine that cause allergic symptoms such as itching and nasal congestion. Paracetamol exerts analgesic and antipyretic effects by centrally inhibiting cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby lowering pain perception and body temperature.

Side Effects

Adverse reactions to Jolastic are generally mild but may vary among individuals.

Common Side Effects

  • Drowsiness: mild sedation or sleepiness.
  • Dry mouth: reduced salivation.
  • Nausea: mild stomach upset.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling or anaphylaxis.
  • Hepatotoxicity: elevated liver enzymes or liver injury with excessive paracetamol exposure.
  • Cardiac arrhythmia: rare palpitations or irregular heartbeat.

Precautions & Warnings

Before using Jolastic, consider the following safety points.

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Liver disease: use with caution; paracetamol dose may need adjustment.
  • Asthma: chlorphenamine may exacerbate bronchospasm in susceptible individuals.
  • Alcohol: avoid excessive intake as it may increase liver risk.
  • Concomitant CNS depressants: may enhance drowsiness.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Jolastic may interact with several medicines; awareness helps avoid complications.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other antihistamines: additive sedation.
  • Alcohol: increased risk of liver toxicity and CNS depression.
  • Warfarin: paracetamol may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • CYP450 substrates: paracetamol may affect metabolism of certain drugs.
  • CNS depressants (benzodiazepines, opioids): monitor for enhanced sedation.
  • Anticholinergic drugs: may increase dry mouth.

Frequently Asked Questions

Jolastic is an over‑the‑counter oral tablet that combines chlorphenamine maleate and paracetamol to relieve symptoms of allergic rhinitis, the common cold, fever and mild to moderate pain such as headache or sore throat.

Chlorphenamine maleate is a first‑generation H1‑histamine receptor antagonist. By blocking H1 receptors, it prevents histamine‑mediated responses, reducing itching, sneezing, nasal congestion and other allergy‑related symptoms.

The appropriate dose of Jolastic is determined by a prescriber based on the patient’s age, weight, clinical condition and local regulatory guidelines. Patients should follow the dosing instructions provided by their healthcare professional.

Safety data for chlorphenamine maleate and paracetamol in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Jolastic.

To order Jolastic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Jolastic combines an antihistamine (chlorphenamine) with an analgesic/antipyretic (paracetamol), offering both allergy symptom control and pain/fever relief in a single tablet. Alternatives such as cetirizine lack analgesic activity, while ibuprofen provides pain relief but no antihistamine effect, making Jolastic a convenient dual‑action option for many patients.

Store Jolastic at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and keep them out of reach of children.

Jolastic is taken orally with a glass of water. The tablet should be swallowed whole unless otherwise directed by a healthcare professional. It can be taken with or without food, but taking it with food may reduce mild stomach upset.

Serious risks include severe allergic reactions such as rash, swelling or anaphylaxis, and potential liver injury from paracetamol, especially when taken in excess or combined with alcohol. Patients should seek immediate medical attention if they notice signs of an allergic reaction or unexplained jaundice.

Jolastic should be avoided by individuals with known hypersensitivity to chlorphenamine, paracetamol or any excipients, those with severe liver disease, uncontrolled asthma, or who are currently taking monoamine oxidase inhibitors. Pregnant or breastfeeding women should only use it after consulting a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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