Product image of Jonosteril Hd5 (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu) supplied by GNH India

Jonosteril Hd5

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu
Origin:
EU

Jonosteril Hd5 (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu)

Magnesium chloride hexahydrate, potassium chloride, sodium chloride, calcium chloride dihydrate and glucose, the active ingredients in Jonosteril HD5, are an electrolyte solution presented as an intravenous solution for IV use. It provides fluid and electrolyte replacement in patients requiring resuscitation or correction of electrolyte deficiencies.

GNH India supplies Jonosteril HD5 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Jonosteril HD5 is used in clinical situations that involve fluid loss or electrolyte disturbances.

  • Electrolyte replacement: restores sodium, potassium, calcium, magnesium and fluid balance in patients with deficits.
  • Fluid resuscitation: supplies essential ions and volume to support circulatory stability during shock or dehydration.
  • Correction of hypokalemia: raises low potassium levels to normal range.
  • Correction of hypomagnesemia: replenishes magnesium stores.
  • Correction of hypocalcemia: increases calcium concentration in the blood.

How It Works

  • Jonosteril HD5 delivers sodium, potassium, calcium, magnesium ions and glucose directly into the bloodstream via intravenous infusion. The supplied ions replace those lost through illness, surgery or trauma, while glucose provides an energy substrate that facilitates cellular uptake of potassium and improves osmotic balance, thereby restoring normal fluid and electrolyte homeostasis.

Side Effects

Common Side Effects

  • Infusion site irritation: mild redness or discomfort at the catheter site.
  • Transient headache: short‑lasting headache during or after infusion.
  • Mild hypernatremia: slight increase in serum sodium levels.
  • Mild hyperkalemia: slight increase in serum potassium levels.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: dangerous shifts in sodium, potassium, calcium or magnesium.
  • Anaphylactic reaction: rare severe allergic response requiring immediate medical attention.
  • Cardiac arrhythmia: abnormal heart rhythm due to electrolyte disturbances.

Precautions & Warnings

Jonosteril HD5 should be administered with careful clinical monitoring.

  • Baseline assessment: evaluate patient electrolyte levels before infusion.
  • Cardiac risk: adjust infusion rate in patients with known heart disease.
  • Renal impairment: avoid rapid administration in patients with reduced kidney function.
  • Fluid status: monitor blood pressure and signs of fluid overload.
  • Storage: Store at controlled room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Jonosteril HD5 may interact with other medications that affect electrolyte balance.

Major Interactions (Avoid)

  • Calcium channel blockers: additive risk of hypercalcemia.
  • Potassium‑sparing diuretics: may precipitate hyperkalemia.
  • Concurrent IV electrolyte solutions: can cause severe electrolyte overload.

Moderate Interactions (Monitor Closely)

  • Nephrotoxic drugs: require close monitoring of renal function.
  • High‑dose insulin therapy: may shift potassium intracellularly; monitor electrolytes.

Frequently Asked Questions

Jonosteril HD5 is an intravenous electrolyte solution used to replace lost fluids and correct deficiencies of sodium, potassium, calcium, magnesium and glucose in patients who require fluid resuscitation or electrolyte rebalancing, such as after surgery, trauma, or severe dehydration.

The solution provides essential ions—sodium, potassium, calcium, magnesium—and glucose directly into the bloodstream. These components restore normal plasma concentrations, support cellular function, and help maintain osmotic balance, thereby correcting electrolyte disturbances and supporting circulatory volume.

The dose of Jonosteril HD5 is determined by the prescribing clinician based on the patient’s electrolyte levels, fluid status, weight and clinical condition. The healthcare professional calculates the appropriate volume and infusion rate for each individual case.

Safety data for Jonosteril HD5 in pregnancy and lactation are limited. The product should be used only if clearly needed and after a risk‑benefit assessment by the treating physician. Consultation with a specialist is recommended before administration to pregnant or nursing patients.

To order Jonosteril HD5, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Jonosteril HD5 offers a balanced combination of sodium, potassium, calcium, magnesium and glucose in a single formulation, which can reduce the need for multiple separate infusions. Compared with simpler saline solutions, it provides broader electrolyte coverage, making it suitable for complex resuscitation scenarios where multiple deficiencies are present.

Jonosteril HD5 should be stored at controlled room temperature, protected from light and moisture, and kept in its original packaging until use. Do not freeze the solution. Inspect the container for any damage before administration.

Jonosteril HD5 is administered intravenously. The solution is infused through a sterile IV line, with the rate and total volume determined by the prescribing clinician according to the patient’s clinical needs and laboratory results.

The most serious risks include severe electrolyte imbalance, which can lead to cardiac arrhythmias, and rare anaphylactic reactions. Continuous monitoring of electrolyte levels, cardiac rhythm and vital signs during infusion helps mitigate these risks.

Jonosteril HD5 should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled hyperkalemia, hypermagnesemia, hypercalcemia, or severe fluid overload unless closely monitored. Clinicians must assess each patient’s condition before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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