Product image of Jonosteril Na 100 Kohlenhydratfrei (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod) supplied by GNH India

Jonosteril Na 100 Kohlenhydratfrei

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod
Origin:
EU

Jonosteril Na 100 Kohlenhydratfrei (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod)

Magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium chloride dihydrate, the active ingredients in Jonosteril Na 100 Kohlenhydratfrei, are an electrolyte solution presented as a sterile solution for intravenous use. It provides sodium, potassium, calcium, magnesium and chloride ions to restore and maintain fluid and electrolyte balance in patients requiring replacement therapy.

GNH India supplies Jonosteril Na 100 Kohlenhydratfrei as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Jonosteril Na 100 is an electrolyte solution used in clinical situations where fluid and electrolyte balance must be restored or maintained.

  • Fluid replacement: supplies essential electrolytes and water to patients with acute volume loss.
  • Electrolyte replenishment: corrects deficits of sodium, potassium, calcium and magnesium during illness or surgery.
  • Critical care maintenance: supports electrolyte homeostasis in intensive care or peri‑operative settings.
  • Dehydration management: rehydrates patients with combined fluid and electrolyte depletion.

How It Works

  • The solution delivers sodium, potassium, calcium, magnesium and chloride ions directly into the bloodstream via intravenous infusion. These ions participate in osmotic regulation, nerve impulse transmission, muscle contraction and acid‑base balance, thereby restoring extracellular fluid volume and correcting electrolyte disturbances caused by loss, redistribution, or inadequate intake.

Side Effects

Jonosteril Na 100 may be associated with infusion‑related reactions and electrolyte‑related adverse events.

Common Side Effects

  • Mild hypernatremia: transient elevation of serum sodium.
  • Hyperkalemia: modest increase in serum potassium.
  • Local irritation: pain or erythema at the infusion site.
  • Hypocalcemia: occasional drop in calcium levels.
  • Headache or dizziness during rapid infusion.

Serious or Rare Side Effects

  • Severe hypermagnesemia: can cause hypotension, bradycardia, respiratory depression.
  • Cardiac arrhythmias: due to electrolyte imbalance.
  • Anaphylactoid reaction: rare hypersensitivity to solution components.
  • Metabolic alkalosis: from excessive chloride removal.
  • Volume overload: pulmonary edema in patients with compromised cardiac function.

Precautions & Warnings

Jonosteril Na 100 should be used with clinical monitoring and appropriate patient assessment.

  • Renal impairment: adjust infusion rate and monitor electrolytes closely.
  • Cardiac disease: avoid rapid infusion that may precipitate arrhythmias.
  • Fluid overload risk: assess volume status before administration.
  • Electrolyte disorders: correct existing imbalances prior to infusion.
  • Compatibility: verify compatibility with other IV medications before co‑administration.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Electrolyte solutions can interact with other medications that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Loop diuretics: may cause excessive potassium loss when combined.
  • ACE inhibitors/ARBs: increase risk of hyperkalemia.
  • Calcium channel blockers: additive effects on calcium levels.

Moderate Interactions (Monitor Closely)

  • Sodium‑containing drugs: monitor for hypernatremia.
  • Magnesium‑containing antacids: risk of hypermagnesemia.
  • Blood pressure agents: watch for hypotensive effects due to volume expansion.

Frequently Asked Questions

Jonosteril Na 100 is an intravenous electrolyte solution used to replace lost fluids and electrolytes in patients undergoing surgery, experiencing dehydration, or receiving critical care. It helps maintain proper sodium, potassium, calcium, magnesium and chloride levels, supporting normal cellular function and hemodynamic stability.

Magnesium chloride hexahydrate dissociates in the bloodstream to release magnesium ions, which act as cofactors for many enzymatic reactions, help regulate muscle and nerve function, and contribute to the stability of cardiac rhythm. In the context of Jonosteril Na 100, it assists in correcting magnesium deficits while the solution provides other essential electrolytes.

The dose of Jonosteril Na 100 is determined by the prescribing clinician based on the patient’s fluid status, electrolyte measurements, weight, and clinical condition. The healthcare professional calculates the required volume and infusion rate to safely achieve the desired electrolyte balance.

Safety data for Jonosteril Na 100 in pregnancy and lactation are limited. Use is generally reserved for situations where the benefits to the mother outweigh potential risks to the fetus or infant, and only under close medical supervision. Clinicians should evaluate each case individually.

To order Jonosteril Na 100, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Jonosteril Na 100 provides a balanced combination of sodium, potassium, calcium, magnesium and chloride without added carbohydrates, making it suitable for patients requiring carbohydrate‑free fluid therapy. Compared with generic saline or lactated Ringer’s, it offers a broader electrolyte profile, which can reduce the need for additional supplementation in complex clinical scenarios.

The solution should be stored at 2‑8 °C, protected from light, and must not be frozen. Keep the container in its original packaging to avoid moisture exposure. Before use, inspect for particulate matter or discoloration and ensure the infusion set is compatible with the solution.

Jonosteril Na 100 is administered intravenously using a sterile infusion set. The healthcare provider selects an appropriate infusion rate based on the patient’s clinical needs, monitors vital signs and electrolyte levels, and adjusts the rate as required to achieve the target fluid and electrolyte balance.

Serious risks include severe hypermagnesemia, which can cause respiratory depression and cardiac arrhythmias, as well as volume overload leading to pulmonary edema in patients with compromised cardiac function. Rapid infusion may also precipitate electrolyte‑related arrhythmias. Continuous monitoring is essential to detect these complications early.

Jonosteril Na 100 should be avoided in patients with known hypersensitivity to any of its components, those with uncontrolled hyperkalemia, severe hypernatremia, or untreated severe electrolyte imbalances that could be worsened by the infusion. Clinicians must also consider contraindications in patients with severe renal or cardiac failure where fluid overload is a concern.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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