Product image of Jopamiro (Iopamidol) supplied by GNH India

Jopamiro

Active Ingredient:
Iopamidol
Origin:
EU

Jopamiro (Iopamidol)

Iopamidol, the active ingredient in Jopamiro, is an iodinated contrast agent presented as a sterile injectable solution for intraarterial and intravenous use. It provides radiographic contrast for imaging procedures in patients undergoing diagnostic radiology.

GNH India supplies Jopamiro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, imaging centres and clinics worldwide.

Manufacturer / TM Owner

Bracco Österreich Gmbh

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Indications & Clinical Uses

  • Jopamiro (iopamidol) is used in diagnostic radiology to enhance X‑ray based imaging.
  • Angiography: provides clear visualization of blood vessels for accurate assessment.
  • Computed tomography (CT) imaging: improves tissue contrast to aid diagnosis.
  • Urography: enhances visualization of the urinary tract structures.
  • Venography: delineates venous anatomy for precise evaluation.

How It Works

  • Iopamidol contains a high density of iodine atoms that absorb X‑ray photons. After intravenous or intra‑arterial injection, the iodine attenuates the X‑ray beam, increasing radiodensity of blood‑filled structures and extracellular spaces. This temporary contrast enhancement allows radiologists to obtain detailed images of vessels, organs, and urinary pathways during diagnostic procedures.

Side Effects

Adverse reactions may occur following administration of Jopamiro.

Common Side Effects

  • Warm sensation or flushing at the injection site.
  • Nausea or mild vomiting.
  • Headache or dizziness.
  • Metallic taste in the mouth.
  • Transient skin rash or urticaria.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Acute kidney injury (contrast‑induced nephropathy).
  • Thyroid dysfunction due to iodine load.
  • Cardiac arrhythmias or hypotension.
  • Seizures or neurologic disturbances.
  • Pulmonary edema or respiratory distress.

Precautions & Warnings

  • Before using Jopamiro, clinicians should consider several safety measures.
  • Assess renal function: evaluate serum creatinine and eGFR prior to administration.
  • Review allergy history: identify prior reactions to iodinated contrast media.
  • Maintain hydration: ensure adequate fluid intake before and after the procedure.
  • Use lowest effective iodine dose: limit total contrast volume when possible.
  • Monitor thyroid status: especially in patients with known thyroid disease.
  • Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture and light.

Avoid Interactions

Iopamidol may interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • Concurrent nephrotoxic drugs: increase risk of renal impairment.
  • High‑dose iodinated contrast with radioactive iodine therapy: may interfere with treatment.
  • ACE inhibitors in patients with renal insufficiency: elevate risk of contrast‑induced nephropathy.
  • Metformin in renal‑impaired patients: potential for lactic acidosis.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may affect renal clearance of contrast.
  • Beta‑blockers: can mask early signs of anaphylaxis.
  • Thyroid hormone replacement: monitor thyroid function tests after contrast exposure.

Frequently Asked Questions

Jopamiro contains iopamidol, an iodinated contrast agent used to improve visualization during diagnostic imaging procedures such as angiography, CT scans, urography, and venography. It is administered intravenously or intra‑arterially to temporarily increase the radiodensity of blood vessels and organs, allowing radiologists to obtain clearer images for accurate diagnosis.

Iopamidol works by providing a high concentration of iodine atoms that absorb X‑ray photons. When injected into the vascular system, the iodine attenuates the X‑ray beam, creating a contrast between blood‑filled structures and surrounding tissues. This enhanced radiodensity enables detailed imaging of vessels, organs, and urinary pathways during radiographic examinations.

The dose of Jopamiro is determined by the prescribing physician based on the specific imaging study, patient weight, renal function, and the required iodine load. Healthcare professionals calculate the appropriate volume and concentration for each procedure, and the medication is administered under controlled clinical conditions.

Safety of iopamidol in pregnancy and lactation has not been definitively established. It is generally classified as a category where benefits must outweigh potential risks. Clinicians should evaluate the necessity of contrast‑enhanced imaging in pregnant or nursing patients and consider alternative modalities when possible.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Jopamiro. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Jopamiro (iopamidol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other low‑osmolality agents such as iohexol or iopromide, iopamidol provides similar image quality while potentially reducing the incidence of discomfort and adverse reactions, though individual patient factors guide selection.

Jopamiro should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture, and freezing. Before use, inspect the solution for particulate matter or discoloration, and allow it to reach room temperature if stored in a cooler environment.

Jopamiro is supplied as a sterile injectable solution for intravenous or intra‑arterial administration. The medication is injected by a qualified healthcare professional using aseptic technique, typically through a peripheral or central venous line, or directly into an arterial catheter, depending on the imaging procedure being performed.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute kidney injury, thyroid dysfunction from iodine load, and rare cardiac events like arrhythmias. Prompt recognition and management of these reactions are essential, and patients with known risk factors should be closely monitored.

Jopamiro is contraindicated in patients with a known hypersensitivity to iopamidol or any iodinated contrast media, those with uncontrolled severe asthma, and individuals with unstable renal function where the risk of contrast‑induced nephropathy outweighs diagnostic benefit. Clinicians should also exercise caution in patients with thyroid disorders, heart failure, or a history of severe allergic reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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