Product image of Jopamiro (Iopamidol) supplied by GNH India

Jopamiro

Active Ingredient:
Iopamidol
Origin:
EU

Jopamiro (Iopamidol)

Iopamidol, the active ingredient in Jopamiro, is an iodinated contrast media presented as a sterile injectable solution for intra‑articular, intrathecal, and intravenous use. It enhances X‑ray attenuation, thereby improving the visibility of anatomical structures during diagnostic and interventional imaging procedures in patients of all ages.

GNH India supplies Jopamiro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, diagnostic imaging centres, and clinics worldwide, ensuring consistent quality and regulatory compliance across markets, with a focus on timely delivery and support for procurement teams.

Manufacturer / TM Owner

Bracco Österreich Gmbh

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Indications & Clinical Uses

Iopamidol is employed as an iodinated contrast agent to improve radiographic visualization across several imaging modalities.

  • Computed Tomography (CT): enhances differentiation of soft‑tissue, vascular, and organ structures during CT scans.
  • Angiography: increases contrast of blood vessels, aiding diagnosis and therapeutic planning in arterial and venous studies.
  • Myelography: provides clear delineation of the spinal canal and nerve roots for diagnostic evaluation of the central nervous system.

How It Works

  • Iopamidol contains a high density of iodine atoms that absorb X‑ray photons. After intravenous, intrathecal, or intra‑articular administration, the iodine increases attenuation of the X‑ray beam within vascular and extracellular compartments, creating a temporary radiodensity difference between tissues. This contrast enhancement allows radiologists to distinguish anatomical structures and pathological lesions with greater clarity during imaging procedures.

Side Effects

Iopamidol may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Warm sensation at injection site
  • Nausea
  • Headache
  • Metallic taste
  • Transient flushing
  • Mild hypotension

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Contrast‑induced nephropathy
  • Cardiac arrhythmia
  • Pulmonary edema
  • Severe hypotension or shock

Precautions & Warnings

Prior to administration, several safety considerations should be observed.

  • Assess renal function: evaluate serum creatinine before use in patients with kidney disease.
  • Screen for iodine allergy: obtain a detailed history of hypersensitivity to iodinated contrast.
  • Hydration: ensure adequate fluid intake before and after the procedure to reduce nephrotoxicity risk.
  • Avoid in uncontrolled hyperthyroidism: iodine load may exacerbate thyroid hormone release.
  • Pregnancy and lactation: use only if clearly needed, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, protect from light and moisture in the original packaging.

Avoid Interactions

Iopamidol can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Concurrent use of high‑dose nephrotoxic agents (e.g., aminoglycosides, NSAIDs): increased risk of renal injury.
  • Combination with metformin in patients with impaired renal function: risk of lactic acidosis; discontinue metformin before and after administration.
  • Co‑administration with iodinated thyroid medications: may cause excessive iodine load.

Moderate Interactions (Monitor Closely)

  • Use with beta‑blockers: may mask signs of contrast reaction.
  • Concurrent diuretics: may affect fluid balance, monitor renal function.
  • Administration with other contrast agents: cumulative iodine exposure should be evaluated.

Frequently Asked Questions

Jopamiro is an iodinated contrast agent used to enhance the quality of X‑ray‑based imaging studies such as computed tomography (CT), angiography, and myelography. By increasing the attenuation of X‑ray beams, it helps radiologists visualize blood vessels, organs, and spinal structures more clearly during diagnostic and interventional procedures.

Iopamidol contains a high concentration of iodine atoms that absorb X‑ray photons. When injected, the iodine increases the radiodensity of blood and extracellular fluid, creating a temporary contrast between tissues. This difference allows imaging equipment to produce sharper, more detailed pictures of anatomical structures.

The dose of Jopamiro is determined by the prescribing clinician based on the specific imaging study, patient weight, renal function, and the route of administration. Healthcare professionals calculate the appropriate volume and concentration to achieve optimal contrast while minimizing risk.

Safety data for Iopamidol in pregnancy and lactation are limited. It should only be used when clearly needed and after a risk‑benefit assessment by the treating physician. Breastfeeding mothers should discuss potential exposure with their healthcare provider, as the drug may be excreted in milk.

To order Jopamiro, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Jopamiro (Iopamidol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image enhancement while reducing the incidence of discomfort and adverse renal effects, making it a preferred choice for many diagnostic imaging procedures.

Jopamiro should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze the product, and inspect the vial for particulate matter before use.

Jopamiro is administered by a qualified healthcare professional via intra‑articular, intrathecal, or intravenous injection, depending on the imaging study. The injection is typically performed using a sterile technique, and the volume is adjusted to the specific diagnostic requirement and patient characteristics.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute kidney injury, and rare cardiac events like arrhythmias or hypotensive shock. Patients with known iodine allergy, impaired renal function, or uncontrolled thyroid disease should be closely monitored.

Jopamiro should be avoided in individuals with a documented severe hypersensitivity to iodinated contrast media, uncontrolled hyperthyroidism, or severe renal impairment where alternative imaging methods are feasible. Pregnant or breastfeeding women should only receive it when the diagnostic benefit outweighs potential risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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