Product image of Kabiven Peripheral (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Kabiven Peripheral

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Kabiven Peripheral (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredients in Kabiven Peripheral, are a parenteral nutrition solution presented as an intravenous solution for intravenous use. It provides essential amino acids to patients who cannot receive enteral feeding.

GNH India supplies Kabiven Peripheral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and intensive‑care units worldwide.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

Kabiven Peripheral is used in parenteral nutrition to support protein and nitrogen balance in patients unable to receive enteral feeding.

  • Parenteral nutrition: Provides essential amino acids for patients who cannot receive enteral feeding.
  • Surgical patients: Helps maintain protein synthesis and nitrogen balance during the peri‑operative period.
  • Critically ill patients: Supports metabolic needs and prevents catabolism in intensive‑care settings.

How It Works

  • Kabiven Peripheral delivers a balanced mixture of essential amino acids directly into the bloodstream. These amino acids serve as substrates for protein synthesis, replenish nitrogen stores, and support tissue repair and metabolic functions in patients who cannot obtain nutrition through the gastrointestinal tract.

Side Effects

Common Side Effects

  • Hyperglycemia: Elevated blood glucose levels during infusion.
  • Electrolyte imbalance: Changes in serum potassium, sodium or calcium.
  • Infusion site reactions: Redness, pain or swelling at the catheter site.
  • Mild nausea: Transient feeling of nausea during or after infusion.
  • Fever: Low‑grade temperature rise.
  • Increased blood urea nitrogen: Indicative of protein metabolism.

Serious or Rare Side Effects

  • Anaphylactic reaction: Severe allergic response requiring immediate medical attention.
  • Metabolic acidosis: Significant drop in blood pH.
  • Severe hypernatremia: Critically high sodium levels.
  • Hepatic dysfunction: Abnormal liver enzyme elevations.

Precautions & Warnings

Kabiven Peripheral should be used with careful clinical monitoring.

  • Renal impairment: Monitor renal function and adjust infusion rate.
  • Liver disease: Assess hepatic function before initiation.
  • Electrolyte disturbances: Check serum electrolytes regularly.
  • Hyperglycemia risk: Monitor blood glucose levels during therapy.
  • Pregnancy and lactation: Use only if potential benefit outweighs risk.
  • Store at 2‑8°C: Keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Kabiven Peripheral may interact with other intravenous therapies.

Major Interactions (Avoid)

  • Concurrent high‑dose amino acid solutions: Risk of amino acid overload.
  • Calcium‑containing IV solutions: May precipitate when mixed.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: May increase electrolyte loss.
  • Insulin therapy: May require dose adjustment due to glucose changes.
  • Renal replacement therapy: May affect amino acid clearance.

Frequently Asked Questions

Kabiven Peripheral is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential amino acids to patients who cannot receive nutrition through the gastrointestinal tract, helping to maintain protein synthesis, nitrogen balance, and overall metabolic stability.

The mixture provides the nine essential amino acids required for protein synthesis. Delivered directly into the bloodstream, these amino acids become building blocks for new proteins, support tissue repair, and help preserve lean body mass while maintaining nitrogen equilibrium in patients receiving total parenteral nutrition.

The dose is individualized and set by the prescribing clinician based on the patient’s weight, clinical condition, nitrogen requirements, and laboratory values. Healthcare professionals calculate the appropriate volume and infusion rate to meet each patient’s specific nutritional needs.

Safety data in pregnancy and lactation are limited. Kabiven Peripheral should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Kabiven Peripheral offers a balanced profile of essential amino acids comparable to other commercial parenteral amino acid formulations. Differences among products may include concentration, osmolarity, and specific amino‑acid ratios, which can affect compatibility with other IV fluids and the choice of infusion site.

Store Kabiven Peripheral at 2‑8 °C, protected from light. Do not freeze or shake the container. Keep the solution in its original packaging until use and discard any product that appears discolored or has particulate matter.

Kabiven Peripheral is administered intravenously, typically through a peripheral or central venous catheter. The solution may be diluted according to the manufacturer’s instructions, and the infusion rate is set by the clinician based on the patient’s prescribed daily amino‑acid requirement.

Serious risks include anaphylactic reactions, severe metabolic disturbances such as metabolic acidosis or hypernatremia, and hepatic dysfunction. Prompt recognition and medical intervention are essential if any of these severe adverse events occur.

Kabiven Peripheral should be avoided in patients with known hypersensitivity to any of its amino‑acid components, severe hepatic failure, uncontrolled metabolic disorders, or in situations where the risk of amino‑acid overload outweighs the nutritional benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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