Product image of Kabiven Peripheral (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Kabiven Peripheral

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Kabiven Peripheral (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Kabiven Peripheral, is a parenteral nutrition presented as a solution for injection for intravenous use. It provides essential amino acids for patients unable to receive adequate enteral nutrition.

GNH India supplies Kabiven Peripheral as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Kabiven Peripheral is used in parenteral nutrition to support patients with insufficient oral or enteral intake.

  • Inadequate oral or enteral intake: provides a complete amino acid profile to meet protein requirements.
  • Post‑operative nutritional support: helps maintain nitrogen balance during recovery.
  • Critical care patients requiring amino acid supplementation: supports metabolic needs in intensive care settings.

How It Works

  • Kabiven Peripheral delivers a balanced mixture of essential amino acids directly into the bloodstream, supplying substrates for protein synthesis, replenishing nitrogen stores, and supporting cellular metabolism. The amino acids serve as precursors for neurotransmitters, hormones, and immune mediators, thereby addressing the metabolic demands of patients who cannot obtain nutrition through the gastrointestinal tract.

Side Effects

Kabiven Peripheral may be associated with infusion‑related adverse reactions and metabolic disturbances.

Common Side Effects

  • Hyperglycemia: elevated blood glucose levels during infusion.
  • Electrolyte imbalance: changes in potassium, sodium, or calcium concentrations.
  • Phlebitis: inflammation at the infusion site.
  • Metabolic acidosis: decreased blood pH in susceptible patients.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe hypersensitivity requiring immediate intervention.
  • Hyperosmolarity-related complications: renal dysfunction or cerebral edema.
  • Sepsis: infection related to catheter or contaminated solution.
  • Thrombophlebitis: clot formation with vein inflammation.

Precautions & Warnings

When using Kabiven Peripheral, clinicians should observe several safety considerations.

  • Patient assessment: evaluate renal and hepatic function before initiation.
  • Monitoring: check blood glucose, electrolytes, and acid‑base status regularly.
  • Compatibility: verify compatibility with other IV drugs and avoid mixing in same line unless proven safe.
  • Volume overload: assess fluid status to prevent circulatory overload.
  • Infusion rate: administer according to prescribed rate to reduce risk of metabolic complications.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Kabiven Peripheral can interact with certain medications and solutions administered intravenously.

Major Interactions (Avoid)

  • Insulin therapy: concurrent high‑dose insulin may cause severe hypoglycemia.
  • Loop diuretics: may exacerbate electrolyte disturbances, especially potassium loss.
  • Calcium‑containing solutions: can precipitate when mixed with certain amino acid solutions.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: amino acids may affect coagulation parameters; monitor INR or aPTT.
  • Beta‑adrenergic agonists: may influence potassium shifts; watch serum potassium.
  • Other parenteral nutrition components: ensure total nutrient load does not exceed recommended limits.

Frequently Asked Questions

Kabiven Peripheral is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential amino acids to patients who cannot meet their protein and caloric needs through oral or enteral feeding, such as those in postoperative recovery, critical care, or with chronic malabsorption.

The mixture provides the building blocks for protein synthesis and nitrogen balance. By delivering essential amino acids directly into the bloodstream, it supports cellular repair, immune function, and metabolic processes that would otherwise depend on dietary intake, helping maintain physiological homeostasis.

The dose of Kabiven Peripheral is individualized. A qualified prescriber determines the volume and infusion rate based on the patient’s weight, metabolic needs, renal and hepatic function, and overall nutritional plan. No standard dosing can be stated without a clinical assessment.

Safety data for Kabiven Peripheral in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Kabiven Peripheral offers a balanced profile of ten essential amino acids, similar to other commercial mixes such as Clinimix or Aminoplas. Differences may lie in individual amino‑acid concentrations, osmolarity, and compatibility with other nutrients. Choice depends on institutional protocols, patient-specific needs, and compatibility with the overall nutrition regimen.

Kabiven Peripheral must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required by the administration protocol.

The product is supplied as a sterile solution for injection and is administered intravenously, usually via a dedicated infusion line. The prescriber sets the infusion rate based on the patient’s nutritional prescription, and infusion pumps are commonly used to ensure accurate delivery.

Serious risks include anaphylactic reactions, hyperosmolarity‑related complications such as renal dysfunction or cerebral edema, and catheter‑related infections (sepsis). Continuous monitoring of vital signs, blood glucose, electrolytes, and acid‑base status is essential to detect these events early.

Kabiven Peripheral is contraindicated in patients with known hypersensitivity to any of its amino‑acid components, those with severe metabolic disorders that cannot be corrected, and individuals with uncontrolled hyperglycemia or severe electrolyte imbalances where the solution could exacerbate the condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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