Product image of Kabiven (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Kabiven

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Kabiven (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredient in Kabiven, is a parenteral nutrition presented as a solution for injection for intravenous use. It provides essential amino acids to patients who cannot receive enteral feeding, supporting protein synthesis and metabolic needs.

GNH India supplies Kabiven as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Austria Gmbh

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Indications & Clinical Uses

Kabiven is an amino acid solution used in parenteral nutrition to meet protein and metabolic requirements.

  • Parenteral nutrition for patients unable to receive enteral feeding: provides essential amino acids to sustain nutrition.
  • Postoperative support: assists recovery by supplying building blocks for tissue repair.
  • Critical illness or trauma care: helps maintain nitrogen balance and supports metabolic demands.

How It Works

  • Kabiven delivers a balanced mixture of essential amino acids directly into the bloodstream, bypassing the gastrointestinal tract. The amino acids serve as substrates for protein synthesis, replenish nitrogen stores, and support hepatic metabolism, thereby meeting the metabolic and anabolic needs of patients who cannot obtain nutrition enterally.

Side Effects

Kabiven may be associated with infusion‑related and metabolic adverse reactions.

Common Side Effects

  • Phlebitis at infusion site: inflammation of the vein.
  • Mild hypernatremia: slight increase in serum sodium.
  • Transient elevation of liver enzymes: mild rise in ALT/AST.
  • Electrolyte imbalance: minor shifts in potassium or calcium.

Serious or Rare Side Effects

  • Severe hypersensitivity reaction: anaphylaxis, rash, bronchospasm.
  • Metabolic acidosis: significant drop in blood pH.
  • Hyperammonemia: elevated ammonia levels.
  • Thrombophlebitis: clot formation with vein inflammation.

Precautions & Warnings

When using Kabiven, clinicians should observe several safety measures.

  • Assess renal function: adjust infusion if creatinine clearance is reduced.
  • Monitor liver enzymes: watch for hepatic stress during prolonged use.
  • Check electrolyte levels: especially potassium, calcium, and sodium.
  • Observe for signs of infection at catheter site: prevent sepsis.
  • Use aseptic technique: ensure sterile preparation and administration.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Kabiven can interact with other agents that affect electrolyte or metabolic balance.

Major Interactions (Avoid)

  • Concurrent high‑dose potassium supplements: may cause hyperkalemia.
  • Other parenteral nutrition solutions with overlapping amino acid profiles: risk of excess amino acid load.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: can alter electrolyte balance, requiring monitoring.
  • Anticoagulants (heparin): infusion may affect clotting parameters.
  • Corticosteroids: may increase protein catabolism, affecting nutritional goals.

Frequently Asked Questions

Kabiven is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential amino acids to patients who cannot receive nutrition through the gastrointestinal tract, such as those who are postoperative, critically ill, or have severe trauma.

The solution contains a balanced blend of essential amino acids that are directly infused into the bloodstream. These amino acids become available for protein synthesis, support nitrogen balance, and help meet the metabolic demands of patients who lack enteral intake.

The dose of Kabiven is individualized. A qualified prescriber determines the volume and rate of infusion based on the patient’s weight, clinical condition, and nutritional requirements. No fixed regimen is provided in public information.

Safety data for Kabiven in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Kabiven, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and import documentation.

Kabiven offers a comprehensive essential‑amino‑acid profile in a single sterile solution, simplifying formulation compared with multi‑component mixes. It is comparable to other amino‑acid‑based parenteral nutrition products but may differ in concentration, stability, and specific amino‑acid ratios, which can influence compatibility with other nutrients.

Kabiven must be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, inspect for particulate matter or discoloration and ensure aseptic technique during preparation and administration.

Kabiven is administered intravenously as a sterile solution for injection. It is typically infused through a central or peripheral venous catheter, with the rate and total volume prescribed by the treating physician based on the patient’s nutritional needs.

Serious risks include severe hypersensitivity reactions such as anaphylaxis, metabolic acidosis, hyperammonemia, and thrombophlebitis. Clinicians should monitor patients closely for signs of these events and be prepared to intervene promptly.

Kabiven should be avoided in patients with known hypersensitivity to any of its amino‑acid components, those with uncontrolled electrolyte disturbances, or individuals for whom intravenous nutrition is contraindicated. Clinical judgment is required for each case.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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