Product image of Kacital (Potassium Citrate) supplied by GNH India

Kacital

Active Ingredient:
Potassium Citrate
Origin:
EU

Kacital (Potassium Citrate)

Potassium citrate, the active ingredient in Kacital, is an alkalinizing agent presented as an oral formulation for oral use. It helps correct potassium deficiency, alkalinize urine, and manage metabolic acidosis in appropriate patients, and is employed in clinical settings to reduce calcium oxalate stone formation.

GNH India supplies Kacital as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vital Pharma Nordic Aps

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Indications & Clinical Uses

Kacital (potassium citrate) is used in conditions where potassium balance or urinary alkalinity is clinically relevant.

  • Hypokalemia: restores low serum potassium levels, supporting normal cellular function.
  • Calcium oxalate kidney stones: alkalinizes urine to reduce stone formation and recurrence.
  • Metabolic acidosis: supplies bicarbonate precursors to correct systemic acid‑base disturbances.

How It Works

  • After oral absorption, potassium citrate dissociates into potassium ions and citrate anions. The potassium replenishes extracellular potassium stores, while citrate is metabolized to bicarbonate, raising systemic and urinary pH. This alkalinization decreases calcium oxalate supersaturation and corrects metabolic acidosis.

Side Effects

Potassium citrate may be associated with a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Abdominal discomfort: cramping or bloating.
  • Diarrhea: loose stools, especially at higher doses.
  • Taste alteration: metallic or salty taste perception.

Serious or Rare Side Effects

  • Hyperkalemia: elevated serum potassium that can affect cardiac rhythm.
  • Metabolic alkalosis: excessive bicarbonate leading to high blood pH.
  • Kidney stone aggravation: rare cases of stone formation despite therapy.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

When prescribing potassium citrate, clinicians should consider several safety measures to minimize risk.

  • Assess serum potassium: confirm deficiency before initiating therapy.
  • Monitor renal function: adjust dose in impaired kidney clearance.
  • Evaluate acid‑base status: avoid in patients with existing alkalosis.
  • Review concomitant potassium‑sparing agents: reduce risk of hyperkalemia.
  • Caution in cardiac disease: monitor ECG if high potassium levels develop.
  • Store at ambient temperature: keep below 25 °C in original container, protect from moisture.

Avoid Interactions

Potassium citrate can affect the pharmacokinetics or pharmacodynamics of several medicines.

Major Interactions (Avoid)

  • ACE inhibitors or ARBs: combined effect may cause dangerous hyperkalemia.
  • Potassium‑sparing diuretics (e.g., spironolactone): risk of severe hyperkalemia.

Moderate Interactions (Monitor Closely)

  • Digoxin: elevated potassium can alter digoxin toxicity risk.
  • NSAIDs: may reduce renal potassium excretion, increasing serum levels.
  • Antibiotics such as trimethoprim‑sulfamethoxazole: can raise potassium concentrations.

Frequently Asked Questions

Kacital contains potassium citrate and is used to treat low blood potassium (hypokalemia), to prevent recurrence of calcium oxalate kidney stones by alkalinizing urine, and to correct metabolic acidosis by providing bicarbonate precursors.

Potassium citrate dissociates after oral intake, delivering potassium ions that replenish extracellular potassium and citrate anions that are metabolized to bicarbonate. The resulting increase in systemic and urinary pH reduces calcium oxalate supersaturation and helps correct acid‑base imbalances.

The appropriate dose of Kacital is determined by the prescribing healthcare professional based on the patient’s serum potassium level, renal function, and the specific indication being treated. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for potassium citrate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Kacital, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both potassium citrate and sodium bicarbonate alkalinize urine, but potassium citrate also supplies potassium, making it suitable for patients who need potassium repletion. Sodium bicarbonate does not provide potassium and may increase sodium load, which can be undesirable in certain cardiovascular conditions.

Kacital should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the container tightly closed and out of reach of children.

Kacital is taken orally, usually as a solution or tablet, according to the prescriber’s directions. It may be taken with or without food, but patients should follow any specific instructions regarding timing or fluid intake provided by their healthcare professional.

The most serious risks include hyperkalemia, which can cause cardiac arrhythmias, and metabolic alkalosis, which may lead to neuromuscular symptoms. Rarely, severe allergic reactions such as anaphylaxis can occur. Patients should seek immediate medical attention if they experience symptoms of these conditions.

Kacital should be avoided in patients with known hypersensitivity to potassium citrate, those with severe renal impairment where potassium excretion is compromised, and individuals with existing hyperkalemia or metabolic alkalosis unless closely monitored by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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