Product image of Kalcicur (Calcium) supplied by GNH India

Kalcicur

Active Ingredient:
Calcium
Origin:
EU

Kalcicur (Calcium)

Calcium, the active ingredient in Kalcicur, is a mineral supplement presented as a sterile intravenous solution for intravenous use. It helps restore calcium levels in patients with acute hypocalcemia and supports bone mineralization and cellular functions. It is used in acute care settings to correct low serum calcium, to stabilize cardiac membranes during hyperkalemia treatment, and to support calcium balance during major surgeries.

GNH India supplies Kalcicur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

Manufacturer / TM Owner

Abboxia Ab

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Indications & Clinical Uses

Kalcicur is used intravenously to address conditions related to calcium deficiency or acute disturbances in calcium homeostasis.

  • Acute hypocalcemia: rapid restoration of serum calcium levels to prevent neuromuscular irritability and cardiac complications.
  • Calcium supplementation during major surgery: maintains calcium balance when blood loss or transfusion may lower calcium.
  • Management of hyperkalemia: stabilizes cardiac membranes by counteracting potassium‑induced excitability.
  • Post‑operative osteoporotic fracture care: provides supplemental calcium to support bone healing when oral intake is limited.

How It Works

  • Intravenous calcium delivers calcium ions directly into the bloodstream, raising extracellular calcium concentration. Elevated calcium stabilizes neuronal and cardiac cell membranes by reducing membrane excitability, antagonizes the effects of hyperkalemia, and provides the substrate needed for bone mineralization and various enzymatic processes. The rapid increase in serum calcium corrects hypocalcemia and supports physiological functions that depend on calcium signaling.

Side Effects

Intravenous calcium can be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Local irritation at the infusion site: pain, redness, or swelling.
  • Nausea or vomiting: transient gastrointestinal discomfort.
  • Transient hypotension: mild drop in blood pressure during infusion.
  • Flushing or warmth sensation: feeling of heat in the face or upper body.

Serious or Rare Side Effects

  • Cardiac arrhythmias: abnormal heart rhythms, especially with rapid infusion.
  • Hypercalcemia: excessively high serum calcium leading to confusion or kidney stones.
  • Tissue necrosis: severe extravasation causing tissue damage.
  • Severe allergic reaction: anaphylaxis with rash, bronchospasm, or hypotension.

Precautions & Warnings

When administering Kalcicur, several precautions should be observed to ensure patient safety and product integrity.

  • Verify serum calcium: confirm low calcium levels before infusion.
  • Infuse slowly: administer over 10‑20 minutes to reduce risk of cardiac events.
  • Monitor cardiac function: continuous ECG monitoring during and after infusion.
  • Avoid in severe renal impairment without adjustment: calcium accumulation risk.
  • Use with caution in patients on digoxin: increased risk of toxicity.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Calcium may interact with several medications, altering their efficacy or safety profile.

Major Interactions (Avoid)

  • Calcium and bisphosphonates: concurrent use reduces bisphosphonate absorption; separate administration by at least 30 minutes.
  • Calcium and loop diuretics: may exacerbate hypercalcemia; monitor serum levels closely.
  • Calcium and digitalis glycosides: increased risk of digitalis toxicity due to calcium‑mediated effects on cardiac conduction.

Moderate Interactions (Monitor Closely)

  • Calcium and quinidine: may enhance quinidine’s cardiac effects; ECG monitoring recommended.
  • Calcium and thiazide diuretics: additive hypercalcemic effect; periodic calcium checks advised.
  • Calcium and iron supplements: reduced absorption of both agents; stagger dosing by at least 2 hours.

Frequently Asked Questions

Kalcicur is an intravenous calcium preparation used to correct acute hypocalcemia, support calcium balance during major surgeries, and stabilize cardiac membranes in patients with hyperkalemia. It may also be employed when oral calcium supplementation is not feasible, such as in intensive care or postoperative settings.

Calcium ions are essential for many physiological processes. When administered intravenously, calcium raises extracellular calcium levels, which stabilizes neuronal and cardiac cell membranes, reduces excitability, and counteracts the effects of excess potassium. It also provides the mineral needed for bone mineralization and acts as a co‑factor for numerous enzymatic reactions.

The dose of Kalcicur is determined by the prescribing clinician based on the patient’s serum calcium level, clinical condition, and weight. Healthcare professionals calculate the appropriate volume and rate of infusion to achieve the desired correction while minimizing the risk of rapid calcium shifts.

Safety data for intravenous calcium in pregnancy and lactation are limited. Use of Kalcicur during pregnancy or while breastfeeding should only be considered when the potential benefits outweigh any possible risks, and it must be prescribed and monitored by a qualified healthcare provider.

To order Kalcicur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and any required import documentation.

Kalcicur is supplied as a sterile intravenous solution, offering rapid correction of calcium deficits compared with oral calcium salts, which require gastrointestinal absorption. Compared with other IV calcium products such as calcium gluconate or calcium chloride, Kalcicur’s formulation and concentration are selected for specific clinical protocols, but the choice depends on the therapeutic goal, required calcium load, and patient tolerance.

Kalcicur must be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Before use, inspect the vial for particulate matter or discoloration. Maintain aseptic technique during preparation and administration, and keep the product within the recommended temperature range until the point of infusion.

Kalcicur is administered intravenously by a qualified healthcare professional. The solution is typically diluted in an appropriate compatible fluid and infused slowly, often over 10‑20 minutes, while monitoring the patient’s vital signs and cardiac rhythm. Administration guidelines are provided by the prescriber and the product’s labeling.

Serious risks include cardiac arrhythmias, especially if infused too rapidly, severe hypercalcemia leading to neurological or renal complications, tissue necrosis from extravasation, and rare anaphylactic reactions. Continuous cardiac monitoring and careful infusion techniques are essential to mitigate these risks.

Kalcicur should be avoided in patients with known hypersensitivity to calcium preparations, severe hypercalcemia, or those with conditions that predispose to calcium precipitation such as severe renal failure without appropriate monitoring. It should also be used with caution in patients receiving digoxin, digitalis, or certain diuretics, and only under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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