Product image of Kalcijev Karbonat Krka (Calcium Carbonate) supplied by GNH India

Kalcijev Karbonat Krka

Active Ingredient:
Calcium Carbonate
Origin:
EU

Kalcijev Karbonat Krka (Calcium Carbonate)

Calcium Carbonate, the active ingredient in Kalcijev Karbonat Krka, is a calcium supplement presented as an oral tablet for convenient administration. It helps address calcium deficiency, supports bone mineralization, and contributes to the maintenance of normal bone density in adults, adolescents, and individuals at risk of osteoporosis, including post‑menopausal women.

GNH India supplies Kalcijev Karbonat Krka as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, clinics and health‑care institutions worldwide, ensuring quality and compliance with EU standards.

Manufacturer / TM Owner

Krka-Farma D.O.O.

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Indications & Clinical Uses

Kalcijev Karbonat Krka (calcium carbonate) is used as a mineral supplement to address calcium‑related disorders.

  • Calcium deficiency: Restores adequate calcium levels to support normal physiological functions.
  • Prevention of osteoporosis: Provides elemental calcium to help maintain bone mineral density and reduce bone loss.
  • Support of bone health: Supplies calcium needed for bone remodeling and strength in adults and growing children.
  • Secondary hyperparathyroidism: Assists in managing calcium balance when parathyroid hormone is elevated.

How It Works

  • Calcium carbonate dissociates in the acidic environment of the stomach, releasing calcium ions. The elemental calcium is absorbed primarily in the small intestine via active transport mediated by vitamin D‑dependent calcium‑binding proteins and passive paracellular diffusion. Increased serum calcium contributes to bone mineralization, neuromuscular function, and enzymatic processes, helping to maintain calcium homeostasis. Regulation of parathyroid hormone secretion is facilitated by the rise in extracellular calcium, further supporting skeletal health.

Side Effects

Calcium carbonate is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Constipation: Reduced bowel motility leading to hard stools.
  • Flatulence: Excess gas production causing abdominal discomfort.
  • Belching: Release of gas from the stomach through the mouth.
  • Abdominal discomfort: Mild pain or cramping in the stomach area.
  • Nausea: Feeling of unease and urge to vomit.

Serious or Rare Side Effects

  • Hypercalcemia: Elevated blood calcium levels that may cause weakness, confusion, or cardiac arrhythmia.
  • Kidney stones: Formation of calcium‑based calculi in the urinary tract.
  • Allergic reactions: Rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: Persistent or worsening pain requiring medical evaluation.

Precautions & Warnings

When using Kalcijev Karbonat Krka, consider the following precautions.

  • Assess calcium intake: Evaluate dietary calcium to avoid excess supplementation.
  • Renal function: Use with caution in patients with renal impairment.
  • Vitamin D status: Ensure adequate vitamin D to facilitate calcium absorption.
  • Concurrent medications: Review use of bisphosphonates, thiazide diuretics, and iron supplements.
  • Pregnancy and lactation: Use only under medical supervision.
  • Store at ambient temperature: Keep below 25 °C in the original container, protect from moisture.

Avoid Interactions

Calcium carbonate can affect the absorption or action of several medicines.

Major Interactions (Avoid)

  • Bisphosphonates: Calcium may reduce absorption; separate dosing by at least 2 hours.
  • Tetracycline antibiotics: Calcium chelates tetracyclines, decreasing their efficacy.
  • Iron supplements: Calcium interferes with iron absorption; separate dosing.

Moderate Interactions (Monitor Closely)

  • Thiazide diuretics: May increase risk of hypercalcemia.
  • Vitamin D analogues: May enhance calcium absorption; monitor serum levels.
  • ACE inhibitors: Potential for altered calcium balance; monitor renal function.

Frequently Asked Questions

Kalcijev Karbonat Krka contains calcium carbonate, which is used as a mineral supplement to treat calcium deficiency, help prevent osteoporosis, and support overall bone health in children, adults, and individuals at risk of bone loss.

When ingested, calcium carbonate releases calcium ions in the acidic stomach environment. The calcium is then absorbed in the small intestine, where it contributes to bone mineralization, neuromuscular function, and enzymatic activities, helping maintain normal calcium homeostasis.

The appropriate dose of Kalcijev Karbonat Krka is determined by a qualified health‑care professional based on the patient’s age, clinical condition, dietary calcium intake, and any concurrent medications. The prescriber will specify the exact regimen.

Calcium is an essential nutrient during pregnancy and lactation, but supplementation should only be undertaken under medical supervision. The prescriber will assess the need and safety for each individual case.

To order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Calcium carbonate provides a high elemental calcium content per tablet and is widely used for its cost‑effectiveness. Compared with calcium citrate, it requires an acidic gastric environment for optimal absorption, but both achieve similar clinical outcomes when taken as directed.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep out of reach of children and avoid storing in humid or excessively hot locations.

The product is taken orally, usually with a full glass of water. It can be taken with or without food, but consistency with meals may improve tolerance. Follow the prescriber’s instructions regarding timing relative to other medications.

Serious risks include hypercalcemia, which can cause weakness, confusion, or cardiac arrhythmias, and the formation of kidney stones. Patients should report any persistent abdominal pain, unusual fatigue, or signs of elevated calcium levels to their health‑care provider promptly.

Individuals with known hypersensitivity to calcium carbonate, severe renal impairment, or a history of hypercalcemia should avoid this product unless specifically advised by a physician. It is also contraindicated in patients with conditions that predispose them to calcium stone formation without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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