Product image of Kalcijev Karbonat Krka (Calcium Carbonate) supplied by GNH India

Kalcijev Karbonat Krka

Active Ingredient:
Calcium Carbonate
Origin:
EU

Kalcijev Karbonat Krka (Calcium Carbonate)

Calcium carbonate, the active ingredient in Kalcijev Karbonat Krka, is a calcium supplement presented as an oral dosage form for oral use. It helps address calcium deficiency, supports bone health, and may aid in preventing osteoporosis in adults and at‑risk populations.

GNH India supplies Kalcijev Karbonat Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Kalcijev Karbonat Krka is a calcium supplement used to correct low calcium levels and support skeletal health.

  • Calcium deficiency: restores normal calcium concentrations and promotes bone mineralization.
  • Osteoporosis prevention: provides elemental calcium to help maintain bone density in at‑risk individuals.
  • General calcium supplementation: supports daily calcium intake for adults with dietary shortfalls.

How It Works

  • Calcium carbonate dissociates in the acidic environment of the stomach, releasing elemental calcium ions that are absorbed primarily in the small intestine. The absorbed calcium contributes to hydroxyapatite formation in bone, regulates neuromuscular excitability, and can neutralize excess gastric acid, thereby supporting both skeletal integrity and gastrointestinal comfort.

Side Effects

Calcium carbonate is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Constipation: reduced bowel motility leading to hard stools.
  • Flatulence: excess gas production in the gastrointestinal tract.
  • Belching: release of gas from the stomach.
  • Stomach upset: mild dyspepsia or discomfort.
  • Nausea: feeling of queasiness.
  • Mild hypercalcemia: slight elevation of serum calcium levels.

Serious or Rare Side Effects

  • Severe hypercalcemia: can cause confusion, arrhythmias, or kidney impairment.
  • Kidney stones: calcium crystallization in the urinary tract.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe constipation leading to bowel obstruction.
  • Hypercalciuria: excessive calcium excretion that may affect renal function.

Precautions & Warnings

Before using Kalcijev Karbonat Krka, consider the following safety measures.

  • Assess total calcium intake: ensure combined dietary and supplemental calcium does not exceed recommended daily limits.
  • Monitor renal function: patients with kidney disease may be at higher risk for hypercalcemia.
  • Evaluate gastrointestinal history: individuals prone to constipation should use with caution.
  • Review concomitant medications: certain drugs may interact and affect calcium absorption.
  • Pregnancy and lactation: use only if prescribed by a healthcare professional.
  • Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Calcium carbonate can affect the absorption or action of several medicines.

Major Interactions (Avoid)

  • Bisphosphonates: calcium reduces oral bisphosphonate absorption; separate dosing by at least 2 hours.
  • Tetracycline antibiotics: calcium chelates tetracyclines, decreasing their effectiveness.
  • Iron supplements: calcium interferes with iron absorption; stagger administration.

Moderate Interactions (Monitor Closely)

  • Levothyroxine (thyroid hormone): calcium may lower levothyroxine bioavailability; monitor thyroid levels.
  • Loop diuretics: may increase serum calcium; watch for signs of hypercalcemia.
  • Vitamin D analogs: combined use can raise calcium levels; adjust dosing as needed.

Frequently Asked Questions

Kalcijev Karbonat Krka is an oral calcium carbonate supplement used to correct calcium deficiency, support normal bone metabolism, and help prevent osteoporosis in individuals who need additional calcium beyond dietary sources.

When calcium carbonate reaches the acidic stomach environment, it releases elemental calcium ions. These ions are absorbed in the small intestine, become part of the mineral matrix of bone, and participate in muscle contraction, nerve transmission, and blood clotting. The compound can also neutralize excess gastric acid.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, dietary calcium intake, medical condition, and laboratory results. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Calcium is essential during pregnancy and lactation, but Kalcijev Karbonat Krka should only be used if a healthcare provider advises it. The prescriber will consider the mother’s total calcium needs and any potential interactions with other medications.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Calcium carbonate provides a high elemental calcium content per tablet and is inexpensive, but it requires an acidic environment for optimal absorption. Other forms, such as calcium citrate, are better absorbed in low‑acid conditions. Choice depends on patient tolerance, gastric acidity, and cost considerations.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original container, protect it from moisture, heat, and direct sunlight. Do not use if the packaging is damaged or the tablets appear discolored.

The supplement is taken orally with a full glass of water, preferably with meals to enhance absorption and reduce gastrointestinal discomfort. If multiple doses are prescribed, they should be spaced at least two hours apart from medications that may interact with calcium.

Serious risks include severe hypercalcemia, which can cause confusion, cardiac arrhythmias, and kidney impairment, as well as the formation of kidney stones. Patients experiencing persistent vomiting, severe constipation, or unusual fatigue should seek medical attention promptly.

Individuals with known hypercalcemia, severe renal impairment, or a history of calcium‑containing kidney stones should avoid this supplement unless directed by a physician. It is also contraindicated in patients who are allergic to calcium carbonate or any of its excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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