Product image of Kalcium/Kolekalciferol Citron Evolan (Colecalciferol, Calcium) supplied by GNH India

Kalcium/Kolekalciferol Citron Evolan

Active Ingredient:
Colecalciferol, Calcium
Origin:
EU

Kalcium/Kolekalciferol Citron Evolan (Colecalciferol, Calcium)

Colecalciferol, the active ingredient in Kalcium/Kolekalciferol Citron Evolan, is a dietary supplement presented as an oral tablet for oral use. It provides calcium and vitamin D3 to address calcium deficiency, vitamin D deficiency, and to support bone health in adults and children. By enhancing intestinal calcium absorption and maintaining normal serum calcium levels, it contributes to optimal skeletal mineralization.

GNH India supplies Kalcium/Kolekalciferol Citron Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Kalcium/Kolekalciferol Citron Evolan is a calcium and vitamin D3 supplement that supports mineral metabolism and bone health.

  • Calcium deficiency: helps restore normal calcium levels and supports skeletal development.
  • Vitamin D deficiency: provides vitamin D3 to improve intestinal calcium absorption.
  • Osteopenia or osteoporosis risk: contributes to bone mineral density maintenance.
  • Postmenopausal bone loss: aids in maintaining bone strength.
  • Growth in children: supports proper bone growth during development.

How It Works

  • Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and subsequently in the kidney to the active hormone 1,25‑dihydroxyvitamin D, which binds to the vitamin D receptor in intestinal epithelial cells, up‑regulating transcription of calcium‑transport proteins. The supplied calcium is absorbed via these vitamin D‑dependent pathways, increasing serum calcium and facilitating its incorporation into bone matrix, thereby promoting bone mineralization.

Side Effects

Kalcium/Kolekalciferol Citron Evolan may be associated with the following adverse reactions.

Common Side Effects

  • Gastrointestinal discomfort: mild nausea or abdominal cramps.
  • Constipation: reduced bowel movements.
  • Flatulence: increased intestinal gas.
  • Dry mouth: sensation of oral dryness.

Serious or Rare Side Effects

  • Hypercalcemia: elevated serum calcium causing weakness, confusion, or cardiac arrhythmia.
  • Kidney stones: calcium deposition in the renal tract leading to pain and hematuria.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.

Precautions & Warnings

Before using Kalcium/Kolekalciferol Citron Evolan, consider the following precautions.

  • Assess baseline calcium: measure serum calcium to avoid excess supplementation.
  • Monitor vitamin D status: check 25‑hydroxyvitamin D levels, especially in patients at risk of deficiency.
  • Renal impairment: use with caution in patients with reduced kidney function.
  • Hyperparathyroidism: avoid in uncontrolled hyperparathyroidism due to risk of hypercalcemia.
  • Concurrent thiazide diuretics: be aware of additive calcium‑raising effect.
  • Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture.

Avoid Interactions

Kalcium/Kolekalciferol Citron Evolan can interact with several medicines; awareness of these interactions helps maintain safety.

Major Interactions (Avoid)

  • Thiazide diuretics: may cause excessive calcium accumulation leading to hypercalcemia.
  • Digoxin: increased calcium levels can heighten risk of digoxin toxicity.
  • High‑dose vitamin A supplements: combined excess may precipitate hypercalcemia.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: can reduce calcium absorption.
  • Iron supplements: concurrent intake may impair calcium uptake; separate dosing by at least 2 hours.
  • Corticosteroids: may decrease calcium absorption and increase urinary loss, requiring monitoring.

Frequently Asked Questions

Kalcium/Kolekalciferol Citron Evolan is an oral dietary supplement that provides calcium and vitamin D3. It is used to correct calcium and vitamin D deficiencies, support normal bone mineralization, and help maintain skeletal health in both children and adults.

Colecalciferol (vitamin D3) is first hydroxylated in the liver to 25‑hydroxyvitamin D and then in the kidney to the active form 1,25‑dihydroxyvitamin D. This active hormone binds to vitamin D receptors in the intestine, stimulating the production of calcium‑transport proteins and thereby increasing calcium absorption from the gut.

The appropriate dose of Kalcium/Kolekalciferol Citron Evolan is determined by a qualified healthcare professional. The prescriber considers the patient’s age, baseline calcium and vitamin D levels, dietary intake, and any underlying medical conditions before recommending a specific regimen.

Safety data for this supplement in pregnancy and lactation are limited. It should only be used if the prescribing clinician judges that the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant or nursing should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Kalcium/Kolekalciferol Citron Evolan combines both calcium and vitamin D3 in a single oral formulation, which can simplify dosing compared with taking separate calcium and vitamin D products. Its vitamin D3 component specifically enhances calcium absorption, offering a synergistic effect that some single‑ingredient supplements lack.

Store Kalcium/Kolekalciferol Citron Evolan at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the package is tightly closed to maintain product stability.

The supplement is taken orally, usually with water. It can be swallowed with or without food, but taking it with a meal that contains some fat may improve vitamin D3 absorption. Follow the dosing instructions provided by the prescribing healthcare professional.

The most serious risks include hypercalcemia, which can cause weakness, confusion, cardiac arrhythmias, and kidney stone formation. Rarely, severe allergic reactions such as rash, swelling, or anaphylaxis may occur. Patients should seek medical attention promptly if they experience any of these symptoms.

Individuals with known hypersensitivity to calcium, vitamin D3, or any excipients in the formulation should avoid this product. It is also contraindicated in patients with uncontrolled hyperparathyroidism, severe renal impairment, or those taking medications that could cause dangerous calcium accumulation without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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