Product image of Kalii Chloridum + Natrii Chloridum Kabi (Potassium Chloride, Sodium Chloride) supplied by GNH India

Kalii Chloridum + Natrii Chloridum Kabi

Active Ingredient:
Potassium Chloride, Sodium Chloride
Origin:
EU

Kalii Chloridum + Natrii Chloridum Kabi (Potassium Chloride, Sodium Chloride)

Potassium chloride and sodium chloride, the active ingredients in Kalii Chloridum + Natrii Chloridum Kabi, are electrolytes presented as an intravenous solution for electrolyte replacement therapy. They are used to correct potassium and sodium deficits in patients receiving parenteral nutrition, undergoing surgery, or experiencing acute fluid loss, and are commonly administered in intensive care units to maintain plasma electrolyte balance.

GNH India supplies Kalii Chloridum + Natrii Chloridum Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Polska Sp. Z O.O.

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Indications & Clinical Uses

Kalii Chloridum + Natrii Chloridum Kabi is used to manage electrolyte disturbances, particularly potassium and sodium imbalances, in clinical settings.

  • Hypokalemia: restores low plasma potassium levels to the normal range.
  • Hyponatremia: replenishes sodium to correct serum sodium deficiency.
  • Peri‑operative fluid management: provides essential electrolytes during surgery.
  • Acute diarrhoea or vomiting: replaces losses of potassium and sodium.
  • Severe burns: supports electrolyte balance in extensive fluid loss.

How It Works

  • The solution delivers potassium chloride and sodium chloride directly into the bloodstream, increasing extracellular concentrations of K+ and Na+ ions. Elevated potassium restores membrane potential and supports cardiac and muscular function, while sodium contributes to osmotic balance and fluid distribution. Chloride ions accompany both cations to maintain electrical neutrality, helping to normalize plasma electrolyte levels and prevent cellular dysfunction.

Side Effects

Intravenous administration of potassium and sodium chloride can be associated with several adverse reactions.

Common Side Effects

  • Infusion site irritation or pain.
  • Mild hyperkalemia leading to transient elevated potassium.
  • Mild hypernatremia causing thirst or mild edema.
  • Nausea or vomiting.
  • Phlebitis or vein inflammation.

Serious or Rare Side Effects

  • Cardiac arrhythmias due to rapid potassium rise.
  • Severe hyperkalemia causing muscle weakness or paralysis.
  • Anaphylactic reaction to solution components.
  • Hyperosmolar coma from excessive sodium load.
  • Severe vein thrombosis or embolism.

Precautions & Warnings

Careful assessment and monitoring are essential when using this intravenous electrolyte solution.

  • Assess serum electrolytes before administration: verify potassium and sodium levels.
  • Adjust infusion rate: avoid rapid infusion exceeding recommended limits.
  • Monitor cardiac rhythm: watch for arrhythmias during potassium administration.
  • Avoid use in patients with severe renal impairment without dose adjustment.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Electrolyte solutions can interact with other medications, affecting safety and efficacy.

Major Interactions (Avoid)

  • ACE inhibitors or ARBs: may increase risk of hyperkalemia.
  • Potassium‑sparing diuretics (e.g., spironolactone): can cause dangerous potassium accumulation.
  • Trimethoprim‑sulfamethoxazole: potentiates hyperkalemia.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may reduce renal potassium excretion.
  • Other high‑sodium IV fluids: risk of hypernatremia if combined.
  • Digoxin: serum potassium levels influence digoxin toxicity.

Frequently Asked Questions

Kalii Chloridum + Natrii Chloridum Kabi is an intravenous electrolyte solution containing potassium chloride and sodium chloride. It is used to correct low potassium and sodium levels in patients who need rapid electrolyte replacement, such as those with hypokalemia, hyponatremia, peri‑operative fluid loss, severe diarrhoea, or extensive burns.

When infused, potassium chloride releases potassium ions that help restore normal membrane potential, supporting cardiac and muscular activity. Sodium chloride provides sodium and chloride ions, which maintain extracellular fluid volume and osmotic balance. Together they normalize plasma electrolyte concentrations, preventing cellular dysfunction caused by deficiencies.

The dose of Kalii Chloridum + Natrii Chloridum Kabi is individualized. A qualified prescriber determines the amount and infusion rate based on the patient’s serum electrolyte levels, clinical condition, renal function, and overall fluid balance. No standard dosing regimen is provided here.

Safety in pregnancy and lactation depends on the clinical situation. Electrolyte replacement may be necessary, but the prescriber must weigh potential benefits against risks. Potassium and sodium are essential nutrients, yet dosing should be carefully monitored. Consultation with a healthcare professional is required before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Kalii Chloridum + Natrii Chloridum Kabi combines both potassium and sodium chloride in a single IV bag, offering a convenient way to address dual electrolyte deficits. Some alternatives provide only one electrolyte or require separate bags, which may increase preparation time. The combined formulation can simplify dosing when both ions need replacement, but selection should follow clinical guidelines.

The product should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Ensure the container remains sealed until use, and inspect for any discoloration or particulate matter before administration.

It is administered intravenously by a qualified healthcare professional. The solution is infused through a suitable IV line, with the rate adjusted according to the patient’s electrolyte status and clinical protocol. Continuous monitoring of vital signs and serum electrolytes is recommended during infusion.

The most serious risks include rapid elevation of serum potassium leading to cardiac arrhythmias, severe hypernatremia causing neurological complications, and rare anaphylactic reactions. Close monitoring of cardiac rhythm and electrolyte levels is essential to detect and manage these potential complications promptly.

Patients with untreated severe hyperkalemia, uncontrolled hypernatremia, or known hypersensitivity to the product components should not receive it. Additionally, individuals with severe renal impairment require dose adjustment and close supervision, and the solution should be avoided unless a prescriber determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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