Product image of Kalinox 170 Bar (Nitrous Oxide, Oxygen) supplied by GNH India

Kalinox 170 Bar

Active Ingredient:
Nitrous Oxide, Oxygen
Origin:
EU

Kalinox 170 Bar (Nitrous Oxide, Oxygen)

Nitrous oxide, the active ingredient in Kalinox 170 Bar, is a analgesic, anesthetic gas presented as a gas mixture for inhalation use. It provides analgesia and sedation for minor surgical or dental procedures and diagnostic or therapeutic procedures.

GNH India supplies Kalinox 170 Bar as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Air Liquide Sante International

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Indications & Clinical Uses

Kalinox 170 Bar, a nitrous oxide/oxygen gas mixture, is used for analgesia and sedation in procedures involving the nervous system.

  • Dental procedures: provides analgesia and anxiolysis during restorative or surgical dental work.
  • Minor surgical procedures: offers analgesic and sedative effect for minor skin or soft‑tissue surgeries.
  • Diagnostic/therapeutic procedures: facilitates patient comfort and reduces anxiety during endoscopic or imaging examinations.

How It Works

  • Inhaled nitrous oxide produces analgesia and sedation primarily by antagonizing NMDA receptors and enhancing endogenous opioid pathways, while the accompanying oxygen component maintains adequate respiratory oxygenation and supports normal gas exchange during the procedure.

Side Effects

Adverse reactions may occur with nitrous oxide/oxygen inhalation.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Vomiting: occasional emesis during or after inhalation.
  • Dizziness: transient light‑headedness.
  • Headache: mild headache during recovery.
  • Euphoria: brief feeling of well‑being.
  • Increased salivation: excess oral secretions.

Serious or Rare Side Effects

  • Hypoxia: insufficient oxygen leading to cyanosis.
  • Respiratory depression: reduced breathing effort.
  • Severe hypotension: marked drop in blood pressure.
  • Loss of consciousness: unexpected fainting.
  • Seizures: rare convulsive episodes.
  • Allergic reaction: rash, itching, or anaphylaxis.

Precautions & Warnings

Before using Kalinox 170 Bar, consider the following safety measures.

  • Assess respiratory function: ensure the patient can maintain airway patency.
  • Evaluate cardiovascular status: monitor blood pressure and heart rate.
  • Avoid use in severe COPD or obstructive lung disease.
  • Use caution in pregnancy: fetal safety not established.
  • Ensure proper scavenging: limit occupational exposure to waste gas.
  • Store at ambient temperature: keep cylinder in original container, protect from heat and direct sunlight.

Avoid Interactions

Nitrous oxide/oxygen may interact with other substances.

Major Interactions (Avoid)

  • Central nervous system depressants: concurrent opioids or benzodiazepines may cause profound respiratory depression.
  • Volatile anesthetics: combined use can increase risk of hypotension.
  • Methoxyflurane: co‑administration may enhance nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • MAO inhibitors: may intensify sedation.
  • Alcohol: can increase dizziness and impairment.
  • Certain antidepressants: may alter the depth of sedation.

Frequently Asked Questions

Kalinox 170 Bar is a nitrous oxide and oxygen gas mixture used to provide analgesia and sedation during minor surgical, dental, and diagnostic or therapeutic procedures. It helps reduce pain and anxiety while maintaining adequate oxygenation for the patient.

Nitrous oxide acts by blocking NMDA receptors in the central nervous system and enhancing endogenous opioid pathways, which together produce analgesic and sedative effects. The oxygen component ensures sufficient oxygen delivery to support normal respiration during the procedure.

The dose of Kalinox 170 Bar is determined by the prescribing clinician based on the specific procedure, patient characteristics, and monitoring requirements. The healthcare professional adjusts the concentration and flow rate to achieve the desired level of analgesia and sedation.

The safety of nitrous oxide/oxygen inhalation in pregnancy and lactation has not been definitively established. Caution is advised, and the product should only be used if the potential benefits outweigh any possible risks, following a clinician’s assessment.

To order Kalinox 170 Bar, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Kalinox 170 Bar combines nitrous oxide with oxygen, offering rapid onset of analgesia and sedation while maintaining oxygenation. Compared with pure nitrous oxide, the added oxygen reduces the risk of hypoxia. It is generally preferred over volatile anesthetic gases for brief, minimally invasive procedures due to its ease of titration and quick recovery.

Kalinox 170 Bar cylinders should be stored at ambient temperature, away from direct sunlight and heat sources. Keep them in the original packaging, secure them upright, and protect the valve from damage. Follow local regulations for compressed gas storage and handling.

Kalinox 170 Bar is administered via a calibrated inhalation system. The clinician adjusts the flow of the gas mixture to the patient’s breathing circuit, monitoring oxygen saturation and vital signs throughout the procedure to ensure safe and effective analgesia and sedation.

Serious risks include hypoxia, respiratory depression, severe hypotension, loss of consciousness, seizures, and rare allergic reactions. Continuous monitoring of respiratory and cardiovascular parameters is essential to detect and manage these events promptly.

Kalinox 170 Bar should be avoided in patients with severe chronic obstructive pulmonary disease, uncontrolled cardiovascular instability, known hypersensitivity to nitrous oxide or oxygen, and in situations where adequate scavenging cannot be ensured. Clinical judgment is required for each individual case.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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