Product image of Kalipoz Prolongatum (Potassium Chloride) supplied by GNH India

Kalipoz Prolongatum

Active Ingredient:
Potassium Chloride
Origin:
EU

Kalipoz Prolongatum (Potassium Chloride)

Potassium Chloride, the active ingredient in Kalipoz Prolongatum, is an electrolyte supplement presented as an oral dosage form for oral use. It treats hypokalemia and potassium deficiency by restoring normal potassium levels in patients who require potassium repletion.

GNH India supplies Kalipoz Prolongatum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Originating from the European Union, the product meets stringent quality and regulatory standards, enabling reliable global distribution today for healthcare providers.

Manufacturer / TM Owner

Gsk Psc Poland Sp. Z O.O.

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Indications & Clinical Uses

Kalipoz Prolongatum, an oral potassium chloride supplement, is used to correct electrolyte imbalances related to low potassium levels.

  • Hypokalemia: restores serum potassium to the normal range, reducing the risk of cardiac arrhythmias.
  • Potassium deficiency: replenishes intracellular potassium stores, supporting normal muscle and nerve function.
  • Diuretic‑induced potassium loss: compensates for potassium depletion caused by loop or thiazide diuretics.

How It Works

  • Potassium chloride dissociates in the gastrointestinal tract, releasing potassium ions that are absorbed primarily in the small intestine. The absorbed potassium enters the extracellular fluid, increasing serum potassium concentration. Elevated extracellular potassium helps re‑establish the normal electrochemical gradient across cell membranes, which is essential for proper nerve impulse transmission, muscle contraction, and cardiac electrical activity.

Side Effects

Potassium chloride may cause a range of adverse reactions, from mild gastrointestinal discomfort to serious electrolyte disturbances.

Common Side Effects

  • Nausea: mild to moderate feeling of sickness.
  • Abdominal discomfort: cramping or pain in the stomach area.
  • Constipation: reduced bowel movements.
  • Diarrhea: loose stools, especially with higher doses.
  • Taste alteration: metallic or salty taste in the mouth.
  • Hyperkalemia (mild): slight elevation of serum potassium.

Serious or Rare Side Effects

  • Severe hyperkalemia: marked increase in serum potassium that can cause cardiac arrhythmias.
  • Cardiac arrest: life‑threatening heart rhythm disturbance.
  • Anaphylactic reaction: rare severe allergic response.
  • Muscle weakness: due to electrolyte imbalance.
  • Respiratory distress: in extreme cases of hyperkalemia.

Precautions & Warnings

When using Kalipoz Prolongatum, clinicians should observe several safety measures.

  • Baseline assessment: check serum potassium and renal function before initiating therapy.
  • Monitoring: regularly measure potassium levels during treatment.
  • Renal impairment: adjust dose or avoid use in patients with severe kidney disease.
  • Hyperkalemia risk: discontinue if serum potassium exceeds recommended limits.
  • Concomitant drugs: use caution with ACE inhibitors, ARBs, or potassium‑sparing diuretics.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Potassium chloride can interact with several medications, affecting potassium balance.

Major Interactions (Avoid)

  • ACE inhibitors: may cause dangerous hyperkalemia.
  • Angiotensin II receptor blockers (ARBs): increase risk of elevated potassium.
  • Potassium‑sparing diuretics (e.g., spironolactone): can lead to severe hyperkalemia.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may impair renal potassium excretion.
  • Trimethoprim: reduces potassium clearance, raising serum levels.

Moderate Interactions (Monitor Closely)

  • Digoxin: high potassium can reduce digoxin toxicity.
  • Beta‑blockers: may mask symptoms of hyperkalemia.
  • Lithium: potassium levels influence lithium reabsorption.
  • Certain antibiotics (e.g., penicillamine): can affect potassium handling.

Frequently Asked Questions

Kalipoz Prolongatum is an oral potassium chloride preparation used to treat hypokalemia and other conditions of potassium deficiency. It helps restore normal serum potassium levels, supporting proper cardiac, muscular, and neurological function in patients who need potassium repletion.

After oral ingestion, potassium chloride dissociates into potassium ions, which are absorbed mainly in the small intestine. The absorbed potassium enters the extracellular fluid, raising serum potassium concentration and re‑establishing the electrochemical gradient essential for nerve impulse transmission, muscle contraction, and cardiac electrical stability.

The dose of Kalipoz Prolongatum is individualized based on the patient’s serum potassium level, renal function, and clinical condition. The prescribing healthcare professional determines the appropriate amount and frequency, and adjustments are made according to laboratory monitoring.

Safety data for potassium chloride in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Kalipoz Prolongatum provides potassium chloride, which delivers elemental potassium directly and is commonly used for rapid correction of hypokalemia. Alternatives such as potassium gluconate or potassium citrate may have different elemental potassium content and gastrointestinal tolerability, but all serve the same purpose of raising serum potassium levels.

Store Kalipoz Prolongatum at ambient temperature, below 25 °C, in the original packaging. Protect it from moisture, direct sunlight, and extreme temperatures to maintain product stability and potency.

Kalipoz Prolongatum is taken orally, usually with a full glass of water. It may be administered with or without food, but taking it with food can reduce gastrointestinal irritation. The exact administration schedule is set by the prescribing clinician.

The most serious risk is severe hyperkalemia, which can cause life‑threatening cardiac arrhythmias or cardiac arrest. Patients should be monitored for signs of elevated potassium, especially if they have renal impairment or are taking other potassium‑increasing medications.

Kalipoz Prolongatum should be avoided in patients with existing hyperkalemia, severe renal failure, or those taking medications that significantly raise potassium levels (e.g., potassium‑sparing diuretics, ACE inhibitors) unless closely monitored by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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