Product image of Kalium Chloratum Kabi (Potassium Chloride) supplied by GNH India

Kalium Chloratum Kabi

Active Ingredient:
Potassium Chloride
Origin:
EU

Kalium Chloratum Kabi (Potassium Chloride)

Potassium chloride, the active ingredient in Kalium Chloratum Kabi, is an electrolyte supplement presented as an injection solution for intravenous use. It restores potassium levels in patients with hypokalemia and supports cellular function during intravenous potassium replacement therapy.

GNH India supplies Kalium Chloratum Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The product complies with European Union quality standards and is manufactured under GMP conditions, ensuring consistent potency and safety for patients.

Manufacturer / TM Owner

Fresenius Kabi Polska Sp. Z O.O.

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Indications & Clinical Uses

Kalium Chloratum Kabi, a potassium chloride injection, is used in electrolyte management to correct low serum potassium.

  • Hypokalemia: restores serum potassium to the normal range.
  • Intravenous potassium supplementation: provides essential potassium for patients unable to take oral preparations.
  • Peri‑operative care: maintains electrolyte balance in surgical patients at risk of potassium loss.

How It Works

  • Potassium chloride dissociates in plasma to release potassium ions, which are taken up by cells via the Na⁺/K⁺‑ATPase pump, helping to re‑establish the electrochemical gradient across cell membranes. The increased extracellular potassium concentration corrects the deficit that underlies hypokalemia, supporting normal cardiac, muscular and neuronal function. The formulation is isotonic, allowing safe intravenous administration without causing significant shifts in osmolarity.

Side Effects

Intravenous potassium chloride can be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Injection site pain: mild discomfort at the infusion site.
  • Phlebitis: inflammation of the vein used for infusion.
  • Nausea: transient feeling of queasiness.

Serious or Rare Side Effects

  • Severe hyperkalemia: potentially life‑threatening elevation of serum potassium.
  • Cardiac arrhythmias: abnormal heart rhythms including ventricular fibrillation.
  • Tissue necrosis: injury from extravasation of the solution into surrounding tissue.

Precautions & Warnings

When using Kalium Chloratum Kabi, clinicians should observe several safety measures.

  • Assess serum potassium: verify level before infusion.
  • Correct electrolyte imbalances: ensure adequate magnesium and calcium.
  • Infuse slowly: limit rate to ≤10 mEq per hour to reduce cardiac risk.
  • Monitor cardiac rhythm: continuous ECG monitoring during administration.
  • Avoid peripheral veins with irritant risk: use a central line for high‑concentration infusions.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potassium chloride may interact with several drug classes, requiring attention to dosing and monitoring.

Major Interactions (Avoid)

  • ACE inhibitors: may potentiate hyperkalemia.
  • Potassium‑sparing diuretics (e.g., spironolactone): increase risk of severe hyperkalemia.
  • NSAIDs: can reduce renal potassium excretion, raising serum levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask symptoms of hyperkalemia.
  • Digoxin: elevated potassium can increase digoxin toxicity.
  • Renal replacement therapy: adjust dosing based on clearance.

Frequently Asked Questions

Kalium Chloratum Kabi is an intravenous potassium chloride solution indicated for the treatment of hypokalemia and for potassium supplementation in patients who require intravenous therapy, such as those unable to take oral potassium or who need rapid correction of low serum potassium.

Potassium chloride dissociates into potassium ions and chloride in the bloodstream. The potassium ions are taken up by cells via the Na⁺/K⁺‑ATPase pump, restoring the extracellular potassium concentration needed for normal cardiac, muscular and neuronal electrical activity, thereby correcting electrolyte imbalance.

The prescribed dose of Kalium Chloratum Kabi is determined by the treating physician based on the patient’s current serum potassium level, clinical condition, renal function and the desired rate of correction. The healthcare professional calculates the required milliequivalents and sets the infusion rate accordingly.

Safety data for intravenous potassium chloride in pregnancy and lactation are limited. It should only be used when clearly needed and prescribed by a qualified clinician, weighing potential benefits against possible risks to the mother and fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Compared with oral potassium salts, the intravenous formulation of potassium chloride provides a rapid increase in serum potassium and is suitable for patients who cannot tolerate oral intake or need immediate correction. It differs from potassium phosphate or potassium gluconate in its chloride content and osmolarity, which may affect tolerability and infusion protocols.

Kalium Chloratum Kabi should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, inspect for particulate matter and ensure the vial is at room temperature if required for infusion.

The solution is administered intravenously, typically through a peripheral or central venous line. The infusion rate is set by the prescriber, often not exceeding 10 mEq per hour, and the patient is monitored with ECG and serum potassium measurements throughout the administration.

The most critical risks include severe hyperkalemia, which can cause life‑threatening cardiac arrhythmias, and extravasation leading to tissue necrosis. Continuous cardiac monitoring and careful infusion rate control are essential to detect and mitigate these complications promptly.

Kalium Chloratum Kabi is contraindicated in patients with known hypersensitivity to potassium chloride, those with severe hyperkalemia, untreated digitalis toxicity, or significant renal impairment where potassium excretion is compromised, unless a specialist determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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