Product image of Kaliumchlorid Fresenius (Potassium Chloride) supplied by GNH India

Kaliumchlorid Fresenius

Active Ingredient:
Potassium Chloride
Origin:
EU

Kaliumchlorid Fresenius (Potassium Chloride)

Potassium chloride, the active ingredient in Kaliumchlorid Fresenius, is an electrolyte replacement presented as an intravenous solution for parenteral use. It restores extracellular potassium levels and corrects hypokalemia in patients requiring rapid potassium repletion.

GNH India supplies Kaliumchlorid Fresenius as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. Our distribution network ensures timely delivery and regulatory compliance across continents.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Kaliumchlorid Fresenius is used to treat conditions associated with low potassium levels.

  • Hypokalemia: restores normal serum potassium concentrations and prevents cardiac arrhythmias.
  • Potassium replacement therapy: provides controlled potassium infusion during postoperative or critical‑care management.
  • Diuretic‑induced potassium loss: compensates for potassium depletion caused by loop or thiazide diuretics.

How It Works

  • Potassium chloride dissociates in plasma to release potassium ions, which are taken up by cells via Na⁺/K⁺‑ATPase pumps, thereby increasing extracellular potassium concentration. The elevated serum potassium restores the electrochemical gradient essential for cardiac myocyte repolarization, nerve impulse transmission, and muscle contraction. Intravenous administration delivers the ion directly into the bloodstream, allowing rapid correction of hypokalemia.

Side Effects

Potassium chloride may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Vein irritation or phlebitis at the infusion site.
  • Mild nausea or abdominal discomfort.
  • Transient hyperkalemia if infused too quickly.
  • Muscle weakness or tingling sensations.

Serious or Rare Side Effects

  • Severe hyperkalemia causing cardiac arrhythmia.
  • Anaphylactic or severe allergic reaction.
  • Cardiac arrest.
  • Metabolic acidosis.

Precautions & Warnings

When using Kaliumchlorid Fresenius, careful clinical monitoring is essential.

  • Patient assessment: verify serum potassium level before initiation.
  • Infusion rate: administer slowly, typically not exceeding 10‑20 mEq per hour, to avoid rapid shifts.
  • Cardiac monitoring: observe ECG for arrhythmias during and after infusion.
  • Concomitant medications: adjust dose if patient receives ACE inhibitors, ARBs, or potassium‑sparing diuretics.
  • Renal function: reduce or avoid use in severe renal impairment.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potassium chloride can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • ACE inhibitors, ARBs, or potassium‑sparing diuretics: may cause dangerous hyperkalemia.
  • Sodium polystyrene sulfonate (Kayexalate): can precipitate when mixed with potassium chloride solutions.
  • Digoxin: increased risk of digoxin toxicity in the presence of hyperkalemia.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may reduce renal potassium excretion, enhancing hyperkalemia risk.
  • Beta‑blockers: can mask symptoms of hyperkalemia.
  • Insulin therapy: insulin drives potassium into cells, potentially causing hypokalemia after potassium infusion.

Frequently Asked Questions

Kaliumchlorid Fresenius is an intravenous potassium chloride solution used to correct low blood potassium (hypokalemia) and to provide potassium replacement in patients who have lost the electrolyte due to surgery, diuretic therapy, or critical‑illness conditions.

When administered, potassium chloride dissociates into potassium ions that enter the bloodstream. The ions are then taken up by cells via the Na⁺/K⁺‑ATPase pump, raising extracellular potassium levels, which restores normal cardiac electrical activity, nerve conduction, and muscle function.

The dose is individualized by the prescribing clinician based on the patient’s serum potassium concentration, renal function, and clinical status. The prescriber determines the total amount of potassium to be infused and the appropriate infusion rate.

Safety data in pregnancy and lactation are limited. Use is only recommended when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it should be administered under close medical supervision.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Intravenous Kaliumchlorid Fresenius delivers potassium directly into the bloodstream, allowing rapid correction of severe hypokalemia, whereas oral tablets are absorbed more slowly and are suitable for mild deficiencies. IV therapy is preferred when oral intake is impossible or when immediate potassium repletion is required.

The solution should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the container in its original packaging until use and discard any product that appears discolored or contains particulates.

It is given by intravenous infusion, usually diluted in a compatible carrier fluid. The infusion rate is controlled—commonly not exceeding 10‑20 mEq per hour—to avoid rapid shifts in serum potassium. Administration should be performed by qualified healthcare personnel with cardiac monitoring as needed.

The most critical risks are severe hyperkalemia, which can lead to life‑threatening cardiac arrhythmias or cardiac arrest, and rare anaphylactic reactions. Continuous ECG monitoring during infusion helps detect early signs of these serious events.

Patients with existing hyperkalemia, severe renal impairment, or conditions that predispose to high potassium levels should not receive this product. It is also contraindicated in individuals with known hypersensitivity to potassium chloride or any component of the formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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