Product image of Kaliumchloride Fresenius Kabi (Potassium Chloride) supplied by GNH India

Kaliumchloride Fresenius Kabi

Active Ingredient:
Potassium Chloride
Origin:
EU

Kaliumchloride Fresenius Kabi (Potassium Chloride)

Potassium chloride, the active ingredient in Kaliumchloride Fresenius Kabi, is an electrolyte supplement presented as an intravenous solution for intravenous use. It corrects low blood potassium levels and supports normal cellular function in patients with hypokalemia. GNH India supplies Kaliumchloride Fresenius Kabi as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Nederland B.V.

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Indications & Clinical Uses

  • Kaliumchloride Fresenius Kabi is an intravenous electrolyte that acts on potassium balance pathways to restore normal serum levels.
  • Hypokalemia: restores normal potassium concentrations in patients with low serum potassium.
  • Potassium replacement therapy: provides potassium during surgery, dialysis, or other conditions causing depletion.
  • Cardiac arrhythmia prevention: helps maintain cardiac electrical stability in patients at risk due to potassium deficiency.

How It Works

  • Potassium chloride dissociates after intravenous administration, releasing potassium ions that enter extracellular fluid. The increased extracellular potassium shifts the electrochemical gradient, facilitating repolarization of cell membranes, especially in cardiac and skeletal muscle cells, thereby correcting hypokalemia and supporting normal cellular excitability.

Side Effects

Common Side Effects

  • Pain or irritation at the infusion site.
  • Nausea or vomiting.
  • Mild hyperkalemia symptoms such as muscle weakness.
  • Transient headache.
  • Local phlebitis.
  • Mild hypotension.

Serious or Rare Side Effects

  • Severe hyperkalemia leading to cardiac arrhythmias.
  • Cardiac arrest or sudden death.
  • Anaphylactic reaction.
  • Thrombophlebitis.
  • Life‑threatening electrolyte imbalance.
  • Fatal outcomes in extreme cases.

Precautions & Warnings

When using Kaliumchloride Fresenius Kabi, consider patient‑specific factors and monitor closely.

  • Renal impairment: monitor serum potassium and adjust dose.
  • Cardiac disease: use with caution and observe ECG changes.
  • Concomitant ACE inhibitors/ARBs: increased risk of hyperkalemia.
  • Infusion rate: do not exceed recommended rate to avoid irritation.
  • Electrolyte monitoring: check potassium levels before and after administration.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Kaliumchloride Fresenius Kabi can interact with several medications.

Major Interactions (Avoid)

  • ACE inhibitors: may cause severe hyperkalemia.
  • Potassium‑sparing diuretics: risk of dangerous potassium elevation.
  • NSAIDs: can increase potassium retention.
  • Heparin: may potentiate hyperkalemia.
  • Succinylated gelatin: incompatibility leading to precipitation.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hyperkalemia symptoms.
  • Digoxin: hyperkalemia can increase toxicity.
  • Insulin: rapid intracellular shift of potassium.
  • Albuterol: may lower serum potassium.
  • Lithium: altered renal handling affecting potassium balance.

Frequently Asked Questions

Kaliumchloride Fresenius Kabi is an intravenous potassium chloride solution used to treat hypokalemia and to provide potassium replacement during conditions such as surgery, dialysis, or other situations where potassium loss occurs. It helps restore normal serum potassium levels and supports proper cardiac and muscular function.

After intravenous administration, potassium chloride dissociates into potassium ions that enter the extracellular fluid. The increased extracellular potassium shifts the electrochemical gradient across cell membranes, facilitating repolarization of cardiac and skeletal muscle cells, correcting low potassium levels, and maintaining normal cellular excitability.

The dose of Kaliumchloride Fresenius Kabi is individualized by the prescribing clinician based on the patient’s current serum potassium concentration, renal function, cardiac status, and the rate of potassium loss. The prescriber calculates the required amount to safely raise potassium to the target range.

Safety data for potassium chloride in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional after evaluating the clinical situation.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and necessary import documentation.

Kaliumchloride Fresenius Kabi is an injectable formulation, allowing rapid correction of potassium deficits in acute settings, whereas oral potassium salts are slower and used for chronic management. The IV product offers precise dosing and immediate bioavailability, which is essential for severe hypokalemia or when oral intake is not feasible.

The solution must be stored at 2‑8 °C, kept refrigerated, protected from light, and should never be frozen or shaken. Before use, inspect the container for particulate matter or discoloration, and follow aseptic techniques to prevent contamination during preparation and administration.

Kaliumchloride Fresenius Kabi is administered intravenously by a qualified healthcare professional. The infusion rate is carefully controlled, typically not exceeding 10‑20 mmol per hour, to minimize the risk of local irritation and rapid shifts in serum potassium. Monitoring of cardiac rhythm and serum potassium is recommended during and after infusion.

The most serious risks include severe hyperkalemia, which can cause life‑threatening cardiac arrhythmias or cardiac arrest, as well as anaphylactic reactions and thrombophlebitis at the infusion site. Prompt recognition and immediate medical intervention are essential if these events occur.

Patients with known hypersensitivity to potassium chloride or any component of the formulation should avoid the product. It is also contraindicated in individuals with severe renal failure, uncontrolled hyperkalemia, or conditions where rapid potassium elevation could precipitate dangerous cardiac events.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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