Product image of Kaliumphosphat B. Braun (Dipotassium Phosphate, Potassium Dihydrogen Phosphate) supplied by GNH India

Kaliumphosphat B. Braun

Active Ingredient:
Dipotassium Phosphate, Potassium Dihydrogen Phosphate
Origin:
EU

Kaliumphosphat B. Braun (Dipotassium Phosphate, Potassium Dihydrogen Phosphate)

Dipotassium phosphate, the active ingredient in Kaliumphosphat B. Braun, is an electrolyte supplement presented as an injectable solution for intravenous use. It is employed to correct potassium and phosphate deficiencies and to support cellular metabolism in patients with electrolyte disturbances.

GNH India supplies Kaliumphosphat B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide, providing regulated sourcing, quality assurance, and logistics for healthcare institutions across global markets.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Kaliumphosphat B. Braun is used to replenish electrolytes in conditions affecting phosphate and potassium balance.

  • Hypophosphatemia: restores serum phosphate concentrations to normal levels.
  • Hypokalemia: supplies potassium ions to raise low serum potassium.
  • Peri‑operative electrolyte replacement: provides rapid correction of electrolyte deficits during surgery.
  • Acid‑base disorders: assists in correcting metabolic imbalances associated with phosphate and potassium shifts.

How It Works

  • The solution delivers dipotassium phosphate and potassium dihydrogen phosphate ions directly into the bloodstream. These ions dissociate, increasing extracellular potassium and phosphate concentrations, which are then taken up by cells for ATP synthesis, acid‑base buffering, and membrane potential maintenance. The rapid intravenous administration allows immediate correction of electrolyte deficits.

Side Effects

Intravenous administration of Kaliumphosphat B. Braun may be associated with a range of adverse reactions.

Common Side Effects

  • Injection site pain or erythema.
  • Mild hyperphosphatemia.
  • Transient hypotension.

Serious or Rare Side Effects

  • Severe hyperkalemia leading to cardiac arrhythmias.
  • Metabolic alkalosis.
  • Calcium‑phosphate precipitation causing tissue injury.
  • Anaphylactic reaction.

Precautions & Warnings

Prior to using Kaliumphosphat B. Braun, clinicians should observe several safety considerations.

  • Monitor serum electrolytes: check potassium and phosphate levels before and during infusion.
  • Assess renal function: impaired kidneys may reduce clearance of phosphate and potassium.
  • Avoid rapid infusion: administer over recommended time to prevent cardiovascular effects.
  • Use cautiously in cardiac disease: high potassium can exacerbate arrhythmias.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Kaliumphosphat B. Braun can interact with other medications that affect electrolyte balance.

Major Interactions (Avoid)

  • Concurrent potassium‑sparing diuretics: may cause dangerous hyperkalemia.
  • Co‑administration with calcium‑containing solutions: risk of calcium‑phosphate precipitation.
  • Use with other phosphate salts: can lead to severe hyperphosphatemia.

Moderate Interactions (Monitor Closely)

  • Intravenous bicarbonate therapy: may alter acid‑base status when combined.
  • Loop diuretics: increase renal potassium loss, requiring electrolyte monitoring.
  • ACE inhibitors or ARBs: can potentiate potassium elevation.

Frequently Asked Questions

Kaliumphosphat B. Braun is an intravenous electrolyte supplement used to correct low levels of potassium and phosphate in the blood. It is indicated for conditions such as hypophosphatemia, hypokalemia, peri‑operative electrolyte replacement, and certain acid‑base disorders where rapid restoration of these ions is clinically required.

Dipotassium phosphate dissociates after intravenous infusion, releasing potassium and phosphate ions into the extracellular fluid. The potassium helps re‑establish normal membrane potentials and cardiac function, while phosphate is essential for ATP production, cellular signaling, and buffering of acid‑base balance. Together they support metabolic processes and stabilize electrolyte homeostasis.

The prescribed dose of Kaliumphosphat B. Braun is individualized by the treating clinician based on the patient’s serum electrolyte levels, renal function, clinical status, and the specific indication. The prescriber calculates the amount needed to safely raise potassium and phosphate concentrations to target ranges, following institutional protocols.

Safety data for Kaliumphosphat B. Braun in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Clinicians should evaluate the potential benefits against possible risks and consider alternative therapies when treating pregnant or nursing patients.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and necessary import documentation.

Kaliumphosphat B. Braun provides both potassium and phosphate in a single formulation, which can simplify therapy compared with using separate potassium chloride and phosphate preparations. It offers rapid intravenous correction, whereas oral supplements act more slowly. Choice of product depends on the clinical scenario, required ion concentrations, and compatibility with other IV fluids.

The product should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the vial for particulate matter or discoloration. Keep the solution in its original packaging until administration to maintain sterility and stability.

Kaliumphosphat B. Braun is administered intravenously, typically via a peripheral or central line. The infusion rate is determined by the prescriber and may be adjusted based on real‑time monitoring of serum electrolytes and the patient’s cardiac status. Compatibility with other IV solutions should be confirmed before mixing.

The most serious risks include severe hyperkalemia, which can cause life‑threatening cardiac arrhythmias, and hyperphosphatemia leading to calcium‑phosphate precipitation and tissue injury. Rapid infusion may also provoke hypotension or metabolic alkalosis. Prompt monitoring of electrolytes and cardiac rhythm is essential to mitigate these hazards.

Patients with known hypersensitivity to dipotassium phosphate, potassium dihydrogen phosphate, or any excipients in the formulation should avoid the product. It is also contraindicated in individuals with severe renal failure unable to excrete excess phosphate or potassium, and in those with uncontrolled hyperkalemia or hyperphosphatemia.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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