Product image of Kalms Night (Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V) supplied by GNH India

Kalms Night

Active Ingredient:
Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V
Origin:
EU

Kalms Night (Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V)

Valerian dry extract, the active ingredient in Kalms Night, is a herbal sedative presented as an oral preparation for oral use. It is used to help manage sleep disturbances and insomnia in adults seeking a non‑prescription option.

GNH India supplies Kalms Night as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies worldwide. The company adheres to EU quality standards and provides reliable global distribution.

Manufacturer / TM Owner

G R Lane Health Products Ltd.

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Indications & Clinical Uses

Valerian dry extract is employed as an herbal sedative for conditions affecting sleep.

  • Sleep disturbances: may reduce the time needed to fall asleep and improve sleep continuity.
  • Insomnia: supports better sleep quality in individuals with difficulty maintaining sleep.
  • Mild anxiety related to bedtime: can promote relaxation to facilitate sleep onset.

How It Works

  • Valerian dry extract is thought to enhance gamma‑aminobutyric acid (GABA) activity in the central nervous system, possibly by inhibiting its reuptake or modulating GABA‑A receptors. The exact molecular targets remain incompletely defined, but the overall effect is a reduction in neuronal excitability that promotes a calming effect and facilitates sleep onset.

Side Effects

Kalms Night may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate discomfort.
  • Dizziness: sensation of light‑headedness.
  • Gastrointestinal upset: nausea, stomach discomfort.
  • Dry mouth: reduced salivation.
  • Fatigue: feeling of tiredness during the day.
  • Vivid dreams: unusual or intense dreaming.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Liver enzyme elevation: abnormal liver function tests.
  • Severe skin rash: Stevens‑Johnson‑type reactions.
  • Hallucinations: rare perceptual disturbances.
  • Anaphylaxis: life‑threatening systemic reaction.
  • Persistent insomnia: paradoxical worsening of sleep.

Precautions & Warnings

When using Kalms Night, consider the following safety measures.

  • Medical supervision: use under guidance of a healthcare professional.
  • Age restriction: avoid use in children under 12 years.
  • Alcohol avoidance: do not combine with alcoholic beverages.
  • CNS depressants: caution when taken with other sedatives or antihistamines.
  • Pregnancy and lactation: safety not established; consult a clinician.
  • Operating machinery: refrain from driving or operating heavy equipment until you know how the product affects you.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Kalms Night can interact with other substances that affect the central nervous system.

Major Interactions (Avoid)

  • Alcohol: may intensify sedative effects and increase risk of respiratory depression.
  • Benzodiazepines: combined use can lead to excessive sedation.
  • Opioid analgesics: heightened CNS depression risk.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): may alter sleep patterns.
  • Anticonvulsants: potential additive CNS effects.
  • Other herbal supplements (e.g., St. John’s wort): possible pharmacodynamic interactions.

Frequently Asked Questions

Kalms Night is an over‑the‑counter herbal product that contains valerian dry extract. It is primarily used to help adults who experience difficulty falling asleep or staying asleep, providing a non‑prescription option for managing occasional sleep disturbances and mild insomnia.

Valerian dry extract is believed to influence the GABAergic system in the brain. By enhancing the activity of the inhibitory neurotransmitter GABA, it may reduce neuronal excitability, producing a calming effect that can facilitate the onset of sleep. The precise molecular mechanisms are still being investigated.

The appropriate dose of Kalms Night is determined by the prescribing clinician or according to the product label. Healthcare professionals consider factors such as age, severity of sleep difficulty, and concomitant medications when recommending an individual dosing regimen.

Safety data for valerian dry extract in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Kalms Night.

To request Kalms Night, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any special handling) and necessary import documentation.

Kalms Night differs from synthetic hypnotics such as benzodiazepines or Z‑drugs because it is an herbal preparation containing valerian dry extract. It generally has a milder side‑effect profile but may be less potent for severe insomnia. Patients often choose it for its natural origin and lower risk of dependence.

Store Kalms Night at temperatures below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Kalms Night is taken orally, usually with a glass of water. It is recommended to ingest the product shortly before bedtime, following the dosage instructions provided by the prescriber or printed on the label.

While most adverse events are mild, serious risks include allergic reactions such as rash, swelling, or difficulty breathing, as well as rare liver enzyme elevations and severe skin reactions. Any signs of anaphylaxis or persistent adverse effects should prompt immediate medical attention.

Kalms Night should be avoided by children under 12 years, individuals with known hypersensitivity to valerian or any excipients, patients taking strong central nervous system depressants without medical supervision, and anyone who is pregnant or breastfeeding unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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