Product image of Kalsiumfolinat Lumacina (Folic Acid) supplied by GNH India

Kalsiumfolinat Lumacina

Active Ingredient:
Folic Acid
Origin:
EU

Kalsiumfolinat Lumacina (Folic Acid)

Folic acid, the active ingredient in Kalsiumfolinat Lumacina, is a folate (vitamin B9) presented as an injectable solution for intramuscular or intravenous use. It is employed to prevent and treat folate deficiency and to support patients during pregnancy and in folate‑related anemia.

GNH India supplies Kalsiumfolinat Lumacina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Its distribution network ensures timely delivery across Europe, Asia and the Americas.

Manufacturer / TM Owner

Lumacina Ireland Limited

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Indications & Clinical Uses

Kalsiumfolinat Lumacina, a folate supplement, is indicated for conditions where folate metabolism is compromised.

  • Folate deficiency: restores normal folate levels and prevents related hematologic abnormalities.
  • Pregnancy: reduces the risk of neural tube defects in the developing fetus.
  • Folate‑deficiency anemia: supports red blood cell production and improves anemia symptoms.

How It Works

  • Folic acid acts as a donor of one‑carbon units that are essential for the synthesis of nucleic acids and certain amino acids. By participating in the tetrahydrofolate cycle, it facilitates the formation of purines and thymidylate, which are required for DNA replication and cell division. This biochemical role underlies its ability to correct folate deficiency and support rapidly dividing tissues.

Side Effects

Adverse reactions to Kalsiumfolinat Lumacina are generally uncommon but may occur following intramuscular or intravenous administration.

Common Side Effects

  • Injection site pain: mild discomfort or soreness at the injection site.
  • Nausea: transient feeling of queasiness.
  • Headache: mild to moderate headache.
  • Dizziness: temporary light‑headedness.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare severe skin and mucous membrane disorder.
  • Thrombocytopenia: significant drop in platelet count.
  • Seizures: rare neurologic event, especially in patients with pre‑existing conditions.

Precautions & Warnings

When using Kalsiumfolinat Lumacina, several precautions should be observed to ensure safety and effectiveness.

  • Assess folate status: evaluate baseline folate levels before initiating therapy.
  • Monitor hypersensitivity: watch for signs of allergic reaction during and after administration.
  • Use with caution in epilepsy: folic acid may mask vitamin B12 deficiency, potentially affecting seizure control.
  • Avoid in known folic acid allergy: discontinue immediately if hypersensitivity occurs.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Kalsiumfolinat Lumacina may interact with certain medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Methotrexate: concurrent use can reduce methotrexate efficacy and increase toxicity.
  • Pemetrexed: folic acid supplementation may diminish antitumor activity.

Moderate Interactions (Monitor Closely)

  • Trimethoprim: may potentiate folate deficiency, requiring dose adjustment.
  • Sulfasalazine: can impair folate absorption, reducing therapeutic effect.
  • Phenobarbital: may increase folic acid metabolism, lowering plasma levels.

Frequently Asked Questions

Kalsiumfolinat Lumacina is used to prevent and treat folate deficiency, to support normal fetal development during pregnancy by reducing the risk of neural tube defects, and as an adjunct in the management of anemia that results from inadequate folate levels.

Folic acid serves as a one‑carbon donor in the tetrahydrofolate cycle, enabling the synthesis of purines, thymidylate, and certain amino acids. These components are essential for DNA replication, repair, and cell division, which underpins its role in correcting folate deficiency and supporting rapidly dividing tissues.

The appropriate dose of Kalsiumfolinat Lumacina is determined by the prescribing healthcare professional based on the patient’s clinical condition, age, weight, and laboratory findings. Dosage regimens are individualized and should follow the prescriber’s instructions.

Folic acid is generally considered safe in pregnancy and is recommended to reduce the risk of neural tube defects. However, specific safety data for Kalsiumfolinat Lumacina during breastfeeding are limited, so use should be guided by a healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Kalsiumfolinat Lumacina is an injectable form of folic acid, offering rapid systemic availability compared with oral tablets or capsules. This can be advantageous in patients with malabsorption, severe deficiency, or when immediate correction is required, whereas oral supplements are typically used for routine maintenance.

The product should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. It should be handled in a clean environment, and any unused portion should be discarded according to local regulations.

Kalsiumfolinat Lumacina is administered by a qualified healthcare professional via intramuscular or intravenous injection, according to the prescriber’s instructions. The route, site, and rate of administration are selected based on the patient’s condition and clinical setting.

Serious risks include severe allergic reactions such as anaphylaxis, rare skin disorders like Stevens‑Johnson syndrome, significant drops in platelet count (thrombocytopenia), and, in very rare cases, seizures. Immediate medical attention is required if any of these events occur.

Individuals with a known hypersensitivity to folic acid or any component of the formulation should avoid using Kalsiumfolinat Lumacina. It should also be used with caution in patients with epilepsy, severe renal impairment, or those receiving drugs that strongly interact with folate metabolism.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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