Product image of Kanakion Mm (Phytomenadione) supplied by GNH India

Kanakion Mm

Active Ingredient:
Phytomenadione
Origin:
EU

Kanakion Mm (Phytomenadione)

Phytomenadione, the active ingredient in Kanakion Mm, is a vitamin K presented as a sterile solution for intravenous and oral use. It restores normal clotting in patients with vitamin K deficiency, supports treatment of anticoagulant‑related bleeding, and is used for neonatal prophylaxis of hemorrhagic disease.
GNH India supplies Kanakion Mm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Kanakion Mm provides vitamin K activity to address disorders of coagulation.

  • Vitamin K deficiency: restores functional clotting factor synthesis in deficient patients.
  • Anticoagulant‑related bleeding: counteracts excess anticoagulation to reduce hemorrhage risk.
  • Neonatal hemorrhagic disease prophylaxis: prevents bleeding in newborns at risk of vitamin K deficiency.

How It Works

  • Phytomenadione acts as a cofactor for the gamma‑carboxylation of glutamate residues on clotting factors II, VII, IX and X, enabling their conversion to biologically active forms and thereby restoring normal coagulation pathways.

Side Effects

Phytomenadione may cause adverse reactions in some patients.

Common Side Effects

  • Injection site pain or erythema
  • Nausea or mild gastrointestinal upset
  • Headache or dizziness
  • Transient flushing
  • Mild fever
  • Elevated liver enzymes

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe bleeding or thrombosis
  • Hemolytic anemia
  • Acute renal failure
  • Hypotension
  • Pulmonary edema

Precautions & Warnings

Use Phytomenadione with clinical vigilance to minimize risks.

  • Assess vitamin K status: evaluate baseline coagulation before therapy.
  • Monitor coagulation parameters: check PT/INR regularly during treatment.
  • Use cautiously with anticoagulants: adjust dosing as needed.
  • Avoid in known hypersensitivity to phytomenadione or excipients.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Phytomenadione can alter the effects of several medications.

Major Interactions (Avoid)

  • Warfarin: may reduce anticoagulant effect, increasing clot risk.
  • Broad‑spectrum antibiotics: can disrupt gut flora, affecting vitamin K levels.

Moderate Interactions (Monitor Closely)

  • Heparin: additive anticoagulant effect may increase bleeding.
  • Oral contraceptives: potential increased thrombosis risk.
  • Vitamin E supplements: may interfere with vitamin K metabolism.

Frequently Asked Questions

Kanakion Mm contains phytomenadione, a form of vitamin K, and is used to treat vitamin K deficiency, manage bleeding associated with anticoagulant therapy, and provide prophylaxis against hemorrhagic disease in newborns.

Phytomenadione serves as a cofactor for the gamma‑carboxylation of clotting factors II, VII, IX and X, enabling these proteins to bind calcium and participate effectively in the coagulation cascade, thereby restoring normal clotting function.

The appropriate dose of Kanakion Mm is determined by the prescribing healthcare professional based on the patient’s clinical condition, route of administration, and laboratory monitoring. Dosage should never be self‑adjusted.

Safety data for phytomenadione in pregnancy and lactation are limited. Use only if clearly needed and prescribed by a qualified clinician, who will weigh potential benefits against any possible risks to the mother and infant.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Kanakion Mm provides phytomenadione in both intravenous and oral formats, offering flexibility for acute or maintenance therapy. Compared with synthetic vitamin K analogues, phytomenadione is a natural form with a well‑established safety profile, though clinical choice depends on specific patient needs and local guidelines.

Store Kanakion Mm at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperatures to maintain stability.

Kanakion Mm can be given intravenously for rapid correction of deficiency or orally for ongoing maintenance. Administration route and rate are determined by the treating physician based on the clinical scenario and patient response.

Serious risks include anaphylactic reactions, severe bleeding or thrombosis, hemolytic anemia, and acute renal failure. Prompt medical attention is required if any signs of these severe adverse events occur.

Kanakion Mm should be avoided in individuals with known hypersensitivity to phytomenadione or any formulation components, and used with caution in patients with severe liver disease, uncontrolled hypertension, or those receiving interacting anticoagulant therapies.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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