Product image of Kanamycin-Pos (Kanamycin Monosulphate) supplied by GNH India

Kanamycin-Pos

Active Ingredient:
Kanamycin Monosulphate
Origin:
EU

Kanamycin-Pos (Kanamycin Monosulphate)

Kanamycin, the active ingredient in Kanamycin-Pos, is an aminoglycoside antibiotic presented as a sterile ophthalmic preparation for ocular use. It treats bacterial conjunctivitis, keratitis and other ocular bacterial infections in patients requiring topical therapy.

GNH India supplies Kanamycin-Pos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ursapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Kanamycin-Pos is an aminoglycoside antibiotic indicated for bacterial infections of the eye and related structures.

  • Bacterial conjunctivitis: reduces bacterial load and promotes resolution of infection.
  • Keratitis: eradicates pathogenic bacteria to aid corneal healing.
  • Other ocular bacterial infections: provides broad‑spectrum coverage for susceptible organisms.

How It Works

  • Kanamycin binds to the 30S ribosomal subunit of susceptible bacteria, causing misreading of mRNA and inhibition of protein synthesis. This disruption leads to bactericidal activity, particularly against Gram‑negative ocular pathogens, and helps clear the infection when applied topically to the eye.

Side Effects

Kanamycin‑Pos may cause local and systemic adverse reactions, although many patients tolerate it well.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Excessive tearing or discharge.
  • Transient blurred vision.
  • Mild allergic conjunctivitis.

Serious or Rare Side Effects

  • Systemic ototoxicity with prolonged absorption.
  • Nephrotoxicity in patients with compromised renal function.
  • Severe allergic reaction, including anaphylaxis.
  • Corneal ulceration or perforation.
  • Permanent vision loss in rare cases.

Precautions & Warnings

Before using Kanamycin‑Pos, consider the following safety measures.

  • Assess renal function: adjust use if renal impairment is present.
  • Monitor for ototoxicity: discontinue if hearing changes occur.
  • Avoid in patients with known hypersensitivity to aminoglycosides.
  • Use only for confirmed or strongly suspected bacterial eye infections.
  • Do not combine with other ototoxic ophthalmic agents without supervision.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Kanamycin‑Pos can interact with other medicines; some combinations require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Systemic aminoglycosides: increase risk of cumulative ototoxicity and nephrotoxicity.
  • Loop diuretics: potentiate renal toxicity.
  • Neuromuscular blocking agents: may enhance neuromuscular blockade.

Moderate Interactions (Monitor Closely)

  • Topical ophthalmic anesthetics: raise risk of corneal toxicity.
  • Corticosteroid eye drops: may mask infection signs.
  • NSAID eye drops: could add to ocular irritation.

Frequently Asked Questions

Kanamycin-Pos is a topical ophthalmic preparation containing kanamycin monosulphate. It is prescribed to treat bacterial infections of the eye, including bacterial conjunctivitis, keratitis and other susceptible ocular bacterial conditions.

Kanamycin binds to the bacterial 30S ribosomal subunit, causing misreading of messenger RNA and halting protein synthesis. This bactericidal action eliminates susceptible Gram‑negative and some Gram‑positive organisms that cause eye infections.

The dosing regimen for Kanamycin-Pos is determined by the prescribing clinician based on the severity of the infection, patient age and ocular condition. Healthcare professionals set the number of drops, frequency and duration of therapy.

Kanamycin’s pregnancy category is unknown, and systemic absorption from ocular use is low but not negligible. It should be used during pregnancy or lactation only if the potential benefit justifies any potential risk to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kanamycin‑Pos belongs to the aminoglycoside class, offering broad‑spectrum activity especially against Gram‑negative organisms. Compared with fluoroquinolone eye drops, kanamycin may have a lower risk of developing resistance but carries a higher potential for ototoxicity if systemic absorption occurs.

Kanamycin‑Pos should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from light, moisture and extreme temperature fluctuations to maintain sterility and potency.

The medication is applied as eye drops. The prescriber will instruct the patient on the number of drops per eye, the frequency (e.g., every 2–4 hours), and the total duration of treatment, typically ranging from several days to a week.

Serious risks include systemic ototoxicity and nephrotoxicity if significant absorption occurs, severe allergic reactions such as anaphylaxis, and rare but serious ocular complications like corneal ulceration or vision loss. Immediate medical attention is required if these occur.

Patients with a known hypersensitivity to kanamycin, other aminoglycosides, or any component of the formulation should avoid using Kanamycin‑Pos. It is also contraindicated in individuals with severe renal impairment unless closely monitored by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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