Product image of Kanamycin-Pos (Kanamycin Monosulphate) supplied by GNH India

Kanamycin-Pos

Active Ingredient:
Kanamycin Monosulphate
Origin:
EU

Kanamycin-Pos (Kanamycin Monosulphate)

Kanamycin Monosulphate, the active ingredient in Kanamycin-Pos, is an aminoglycoside antibiotic presented as a sterile ophthalmic preparation for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in patients requiring topical therapy. The product complies with European Union pharmacopeial specifications and is manufactured under GMP conditions.

GNH India supplies Kanamycin-Pos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Ursapharm Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Kanamycin-Pos is used in ophthalmology to treat bacterial infections of the eye surface and cornea.

  • Bacterial conjunctivitis: reduces bacterial load and alleviates redness and discharge.
  • Corneal ulcer (bacterial keratitis): promotes healing by eradicating causative organisms.
  • Post‑operative prophylaxis: prevents bacterial contamination after ocular surgery.
  • Trachoma or other bacterial conjunctival infections: controls infection and limits spread.

How It Works

  • Kanamycin Monosulphate exerts its antibacterial activity by binding to the 30S ribosomal subunit of susceptible bacteria. This interaction interferes with the initiation complex of protein synthesis, causing misreading of mRNA and premature termination of peptide chains, ultimately leading to bacterial cell death. The effect is bactericidal against a broad spectrum of Gram‑negative and some Gram‑positive ocular pathogens.

Side Effects

Kanamycin‑Pos may cause local and systemic adverse reactions, most of which are related to its aminoglycoside class.

Common Side Effects

  • Eye irritation: mild burning or stinging upon instillation.
  • Redness: transient conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Blurred vision: temporary visual disturbance.
  • Itching: mild pruritus of the ocular surface.
  • Photophobia: sensitivity to light.

Serious or Rare Side Effects

  • Corneal epithelial toxicity: ulceration or delayed healing.
  • Allergic reaction: swelling, rash, or eosinophilic conjunctivitis.
  • Systemic ototoxicity: hearing impairment if significant absorption occurs.
  • Nephrotoxicity: renal function impairment in susceptible patients.
  • Anaphylaxis: severe, life‑threatening hypersensitivity.
  • Stevens‑Johnson syndrome: rare mucocutaneous eruption.

Precautions & Warnings

Before using Kanamycin‑Pos, clinicians should consider several safety precautions to minimize risks.

  • Hypersensitivity: confirm no known allergy to kanamycin or other aminoglycosides.
  • Infection type: avoid use in viral, fungal or allergic conjunctivitis.
  • Renal function: assess renal status in patients at risk of systemic absorption.
  • Contact lens wear: discontinue lenses during treatment to reduce irritation.
  • Duration of therapy: limit use to the shortest effective period to prevent toxicity.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Avoid Interactions

Kanamycin‑Pos can interact with other medicines, affecting safety or efficacy.

Major Interactions (Avoid)

  • Nephrotoxic agents (e.g., vancomycin, amphotericin B): increase risk of renal damage.
  • Ototoxic drugs (e.g., loop diuretics, cisplatin): potentiate hearing loss.
  • Neuromuscular blockers (e.g., succinylcholine): may enhance muscle weakness.

Moderate Interactions (Monitor Closely)

  • Other topical antibiotics: risk of additive toxicity or antagonism.
  • Topical anesthetics: may increase corneal irritation.
  • Systemic aminoglycosides: cumulative exposure may raise systemic toxicity.

Frequently Asked Questions

Kanamycin-Pos is an ophthalmic formulation of kanamycin monosulphate used to treat bacterial infections of the eye, including conjunctivitis, keratitis, and to provide prophylaxis after ocular surgery. It targets susceptible Gram‑negative and some Gram‑positive organisms that cause surface and corneal infections.

Kanamycin monosulphate binds to the bacterial 30S ribosomal subunit, disrupting the initiation of protein synthesis. This causes misreading of messenger RNA and premature termination of peptide chains, leading to rapid bacterial cell death and clearance of the infection.

The dosing regimen for Kanamycin-Pos is determined by the prescribing clinician based on the type and severity of the infection, patient age, and response to therapy. The prescriber will specify the number of drops, frequency, and duration appropriate for each case.

Safety data for kanamycin monosulphate in pregnancy and lactation are limited. Because systemic absorption from ocular use is possible, the drug should be used only if the potential benefit justifies any potential risk to the fetus or infant, and under medical supervision.

To order Kanamycin-Pos, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Kanamycin-Pos belongs to the aminoglycoside class, offering broad‑spectrum activity against many Gram‑negative ocular pathogens. Compared with other topical aminoglycosides such as tobramycin or gentamicin, kanamycin has a similar spectrum but may differ in potency, resistance patterns, and tolerability, which the prescriber will consider when selecting therapy.

Kanamycin-Pos should be stored at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from moisture and direct light, and discard any product that appears cloudy or discolored. Follow standard aseptic techniques when handling the ophthalmic solution.

Kanamycin-Pos is applied as eye drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed during treatment.

Serious adverse events, although rare, include corneal epithelial toxicity, severe allergic reactions such as anaphylaxis, systemic ototoxicity, and nephrotoxicity if significant systemic absorption occurs. Patients should be instructed to seek immediate medical attention if they experience worsening pain, vision loss, swelling, rash, or hearing changes.

Kanamycin-Pos should be avoided in individuals with a known hypersensitivity to kanamycin, other aminoglycosides, or any component of the formulation. It is also contraindicated for viral, fungal, or allergic eye conditions, and should be used with caution in patients with compromised renal function or those receiving other ototoxic or nephrotoxic drugs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.