Product image of Kanavig (Moxifloxacin Hydrochloride) supplied by GNH India

Kanavig

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Kanavig (Moxifloxacin Hydrochloride)

Moxifloxacin Hydrochloride, the active ingredient in Kanavig, is a fluoroquinolone antibiotic presented as a 0.5% w/v ophthalmic solution for ocular (topical eye drops) use. It treats bacterial eye infections such as bacterial conjunctivitis, bacterial keratitis and blepharitis in patients requiring antibiotic therapy.

GNH India supplies Kanavig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Novartis Pharma N.V.

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Indications & Clinical Uses

Kanavig (moxifloxacin hydrochloride) is a fluoroquinolone ophthalmic antibiotic used to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load, relieving redness, discharge and irritation.
  • Bacterial keratitis: eradicates causative bacteria, promoting corneal healing and preventing scarring.
  • Blepharitis: controls bacterial overgrowth on the eyelid margin, improving symptoms and reducing recurrence.

How It Works

  • Moxifloxacin hydrochloride inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to the quinolone‑resistance‑determining region of these enzymes, it prevents supercoiling and separation of bacterial DNA, leading to bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Kanavig may cause ocular adverse reactions, ranging from mild irritation to rare serious events.

Common Side Effects

  • Stinging or burning: transient discomfort upon instillation.
  • Redness: mild conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects

  • Corneal ulceration: progressive corneal damage.
  • Anterior uveitis: inflammation of the anterior chamber.
  • Severe allergic reaction: swelling, itching, or rash around the eye.

Precautions & Warnings

Before using Kanavig, consider the following precautions to ensure safe and effective therapy.

  • Indication confirmation: ensure a bacterial eye infection is diagnosed before treatment.
  • Contact lens use: remove lenses prior to instillation and wait before reinserting.
  • Systemic absorption: avoid excessive dosing; monitor for systemic fluoroquinolone effects.
  • Pregnancy and lactation: safety not established; use only if benefits outweigh potential risks.
  • Allergic history: assess for hypersensitivity to fluoroquinolones or any formulation component.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Kanavig can interact with other medications; awareness of these interactions helps minimize risks.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent systemic use may increase risk of tendon rupture.
  • Anticholinergic eye drops: may reduce the antibacterial efficacy of moxifloxacin.
  • Strong CYP450 inhibitors: may alter systemic exposure despite minimal ocular absorption.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may affect corneal healing.
  • Corticosteroid eye drops: monitor for delayed resolution of infection.
  • Other topical antibiotics: avoid overlapping therapy to reduce resistance development.

Frequently Asked Questions

Kanavig is an ophthalmic solution containing moxifloxacin hydrochloride. It is prescribed to treat bacterial eye infections such as bacterial conjunctivitis, bacterial keratitis, and blepharitis, helping to eliminate the causative organisms and relieve associated symptoms.

Moxifloxacin hydrochloride blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing these processes, the drug exerts a bactericidal effect against a wide range of Gram‑positive and Gram‑negative ocular pathogens.

The dosing regimen for Kanavig is determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration appropriate for each case.

Safety data for moxifloxacin ophthalmic use in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by the treating physician.

To order Kanavig, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kanavig belongs to the fluoroquinolone class, similar to ciprofloxacin eye drops. Compared with older fluoroquinolones, moxifloxacin offers a broader spectrum against Gram‑positive organisms and often requires a shorter treatment course, though choice depends on local resistance patterns and physician preference.

Kanavig should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from direct sunlight and moisture. Do not freeze the solution, and keep the cap tightly closed when not in use.

Kanavig is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill the prescribed number of drops. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed before use.

Serious ocular risks include corneal ulceration, anterior uveitis, and severe allergic reactions such as swelling or rash around the eye. If any of these occur, the patient should discontinue the drops and seek immediate medical attention.

Kanavig should not be used by individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with active viral or fungal eye infections where an antibacterial agent would be inappropriate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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