Product image of Kanavig (Moxifloxacin Hydrochloride) supplied by GNH India

Kanavig

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Kanavig (Moxifloxacin Hydrochloride)

Moxifloxacin Hydrochloride, the active ingredient in Kanavig, is a fluoroquinolone presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in patients who require topical antibiotic therapy, offering broad‑spectrum coverage against Gram‑positive and Gram‑negative organisms.

GNH India supplies Kanavig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards. The product conforms to EU quality specifications and is manufactured under GMP conditions.

Manufacturer / TM Owner

Novartis Pharma N.V.

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Indications & Clinical Uses

Kanavig (moxifloxacin hydrochloride) is indicated for bacterial infections of the eye, targeting the ocular surface and corneal tissues.

  • Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness, discharge, and irritation.
  • Bacterial keratitis: eradicates causative organisms to promote corneal healing and preserve visual acuity.
  • Other ocular bacterial infections: treats infections such as blepharitis or postoperative bacterial inflammation by providing broad‑spectrum antibacterial activity.

How It Works

  • Moxifloxacin hydrochloride inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to the ATP‑binding sites of these enzymes, the drug prevents supercoiling and separation of bacterial DNA, leading to bactericidal activity against a wide range of Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Topical ocular administration of Kanavig may be associated with local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Temporary blurred vision.
  • Redness of the conjunctiva.
  • Mild eye irritation or itching.

Serious or Rare Side Effects

  • Allergic contact dermatitis with swelling and erythema.
  • Corneal ulceration or perforation.
  • Severe visual loss or sudden decrease in visual acuity.

Precautions & Warnings

Before prescribing Kanavig, clinicians should consider several precautionary measures to ensure safe and effective use.

  • Hypersensitivity assessment: verify no known allergy to fluoroquinolones or any component of the eye drop.
  • Contact lens use: advise patients to remove lenses before instillation and avoid wearing them until the medication is cleared.
  • Concomitant ocular steroids: use with caution as steroids may mask signs of infection.
  • Systemic fluoroquinolone therapy: evaluate risk of additive systemic exposure.
  • Pregnancy and lactation: consider limited safety data and weigh benefits against potential risks.
  • Store at room temperature: keep the bottle in its original packaging, protect from light and moisture, and discard after the indicated period after opening.

Avoid Interactions

Kanavig can interact with other ophthalmic or systemic agents, influencing efficacy or safety.

Major Interactions (Avoid)

  • Concurrent systemic fluoroquinolone therapy: may increase risk of systemic fluoroquinolone‑related adverse events.
  • Use with topical corticosteroids: can suppress inflammatory response and conceal progression of infection.

Moderate Interactions (Monitor Closely)

  • Co‑administration with other topical antibiotics: potential antagonism or reduced efficacy.
  • Combination with non‑steroidal anti‑inflammatory eye drops: may heighten ocular irritation.
  • Preservative‑containing contact lens solutions: increased risk of corneal toxicity when used shortly after instillation.

Frequently Asked Questions

Kanavig is an ophthalmic solution containing moxifloxacin hydrochloride. It is prescribed to treat bacterial infections of the eye, including bacterial conjunctivitis, bacterial keratitis, and other ocular bacterial conditions, by delivering a broad‑spectrum fluoroquinolone directly to the site of infection.

Moxifloxacin inhibits two essential bacterial enzymes, DNA gyrase (topoisomerase II) and topoisomerase IV. By blocking these enzymes, the drug prevents bacterial DNA replication and transcription, leading to bacterial cell death. This mechanism provides rapid bactericidal activity against a wide range of Gram‑positive and Gram‑negative ocular pathogens.

The dosing regimen for Kanavig is determined by the prescribing clinician based on the specific infection, severity, and patient factors. Typically, the prescriber will advise the number of drops per eye and the frequency of administration, and patients should follow the exact instructions provided on the prescription label.

Safety data for Kanavig in pregnancy and lactation are limited. Health‑care providers should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing women. If treatment is essential, the prescriber may consider the lowest effective dose and monitor the patient closely.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Kanavig. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Kanavig’s active ingredient, moxifloxacin, offers a broader spectrum of activity and higher potency against many resistant strains compared with older fluoroquinolone eye drops such as ciprofloxacin. It also provides good penetration into corneal tissue, which can be advantageous in treating keratitis, while maintaining a similar safety profile.

Kanavig should be stored at room temperature, preferably below 25 °C, in its original container. Keep the bottle protected from light and moisture, and avoid freezing. Once opened, discard any remaining solution after the period indicated on the label, even if some product remains.

Kanavig is applied as eye drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a small pocket, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed before use and re‑inserted only after the medication is cleared.

Serious risks, although rare, include severe allergic reactions such as contact dermatitis, corneal ulceration or perforation, and sudden loss of visual acuity. Patients should seek immediate medical attention if they experience intense eye pain, worsening redness, swelling, or any sudden change in vision while using Kanavig.

Kanavig should not be used by individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any excipients in the formulation. It is also contraindicated in patients who are currently using systemic fluoroquinolones when additive toxicity is a concern, and in those for whom the prescriber determines that the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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