Product image of Kanova Adultos (Glycerol) supplied by GNH India

Kanova Adultos

Active Ingredient:
Glycerol
Origin:
EU

Kanova Adultos (Glycerol)

Glycerol, the active ingredient in Kanova Adultos, is an excipient presented as a rectal suppository for rectal use. It helps to soften stool and facilitate bowel movements in adults experiencing occasional constipation. Its hygroscopic properties draw water into the intestinal lumen, providing a gentle laxative effect without systemic absorption.

GNH India supplies Kanova Adultos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Lainco S.A.

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Indications & Clinical Uses

Glycerol in Kanova Adultos is used as a rectal osmotic laxative to relieve constipation and aid bowel preparation.

  • Occasional constipation: softens stool and promotes evacuation in adults.
  • Bowel preparation: assists in cleansing the colon before diagnostic or surgical procedures.
  • Anal fissure discomfort: provides lubrication and reduces pain during defecation.

How It Works

  • Glycerol exerts its laxative action primarily through an osmotic mechanism. When applied rectally, it draws water into the intestinal lumen, increasing stool hydration and volume. This softens the fecal mass and stimulates peristaltic activity, facilitating the passage of stool. The local lubricating effect also reduces friction during evacuation, while systemic absorption remains minimal.

Side Effects

Glycerol may cause local and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Rectal irritation or burning sensation.
  • Mild spotting of blood.
  • Abdominal cramping.
  • Diarrhea.
  • Nausea.
  • Mild headache.

Serious or Rare Side Effects

  • Severe rectal bleeding.
  • Allergic reaction such as rash, swelling, or anaphylaxis.
  • Electrolyte imbalance from excessive fluid loss.
  • Severe abdominal pain.
  • Infection at the application site.
  • Persistent diarrhea leading to dehydration.

Precautions & Warnings

When considering glycerol suppositories, several safety measures should be observed.

  • Assess bowel habit: confirm constipation before use.
  • Avoid in complete bowel obstruction: risk of perforation.
  • Do not use with severe hemorrhoidal disease: may exacerbate bleeding.
  • Monitor for allergic reactions: discontinue if rash or swelling occurs.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Glycerol can interact with other agents affecting bowel function or electrolyte balance.

Major Interactions (Avoid)

  • Concurrent use of strong stimulant laxatives: increased risk of electrolyte disturbance.
  • Rectal enemas containing irritants: heightened mucosal damage.
  • Anticholinergic drugs: may reduce laxative efficacy.

Moderate Interactions (Monitor Closely)

  • Oral magnesium supplements: additive laxative effect.
  • Diabetes medications: monitor blood glucose if diarrhea occurs.
  • Warfarin: rare reports of altered INR with severe diarrhea.

Frequently Asked Questions

Kanova Adultos is a glycerol‑based rectal suppository designed to soften stool and promote bowel movements in adults with occasional constipation. It is also employed to aid bowel cleansing before diagnostic procedures and to provide lubrication for mild anal discomfort.

Glycerol acts as an osmotic agent. When inserted rectally, it draws water into the colon, increasing stool moisture and volume. This softens the feces, stimulates peristalsis, and adds lubrication, making evacuation easier without significant systemic absorption.

The appropriate dose and frequency are determined by the prescribing healthcare professional based on the patient’s condition and response. The prescriber selects the specific suppository strength and administration schedule that best fits the therapeutic need.

Limited clinical data are available for glycerol suppositories in pregnancy and lactation. Because systemic absorption is minimal, it is generally considered low risk, but use should only occur under medical advice after weighing potential benefits and risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives or sodium phosphate enemas, glycerol offers a gentler, locally acting osmotic effect with minimal systemic absorption. It is less likely to cause electrolyte disturbances but may be slower to act than stimulant agents. Choice depends on patient tolerance, urgency of relief, and clinical context.

Store the suppositories at room temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight. Do not freeze. Ensure the product is kept out of reach of children and used before the expiration date.

Kanova Adultos is inserted rectally. The patient should lie on their side with the upper leg bent toward the abdomen, gently push the suppository into the rectum using a gloved finger, and remain lying down for a few minutes to allow the product to dissolve.

Serious risks include severe rectal bleeding, allergic reactions such as rash or anaphylaxis, and electrolyte imbalance from excessive fluid loss. If any of these occur, discontinue use immediately and seek medical attention.

Kanova Adultos should be avoided in individuals with complete bowel obstruction, severe inflammatory bowel disease flare, known hypersensitivity to glycerol, or active rectal bleeding unrelated to hemorrhoids. Consultation with a healthcare provider is essential before use in these situations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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