Product image of Kantos (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate) supplied by GNH India

Kantos

Active Ingredient:
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Origin:
EU

Kantos (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate)

Beclometasone dipropionate / Formoterol fumarate dihydrate, the active ingredient in Kantos, is an inhaled corticosteroid/long‑acting β2‑agonist (ICS/LABA) combination presented as an inhalation product for inhalation use. It provides maintenance therapy for asthma and chronic obstructive pulmonary disease (COPD) in adults, helping to control airway inflammation and improve bronchodilation, thereby reducing symptoms and exacerbations.

GNH India supplies Kantos as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chiesi Gmbh

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Indications & Clinical Uses

Kantos is an inhaled corticosteroid/long‑acting β2‑agonist used for long‑term control of airway disease.

  • Asthma: maintenance therapy that reduces symptoms, frequency of exacerbations and improves lung function.
  • Chronic obstructive pulmonary disease (COPD): maintenance therapy that helps to decrease breathlessness, reduce exacerbation risk and support overall respiratory health.

How It Works

  • Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, suppressing inflammatory gene expression and reducing airway edema. Formoterol fumarate dihydrate selectively stimulates β2‑adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP levels and causing rapid, sustained bronchodilation. The combined actions provide both anti‑inflammatory and bronchodilatory effects for long‑term respiratory control.

Side Effects

Kantos may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Oral candidiasis: fungal infection of the mouth or throat.
  • Hoarseness: voice changes due to local irritation.
  • Throat irritation: discomfort or soreness after inhalation.
  • Headache: mild to moderate pain.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: sudden worsening of breathing.
  • Severe allergic reaction: anaphylaxis with rash, swelling or difficulty breathing.
  • Cardiac arrhythmia: irregular heart rhythm, especially at high systemic exposure.

Precautions & Warnings

Before prescribing Kantos, clinicians should consider several safety measures.

  • Assess disease control: ensure asthma or COPD is not acutely worsening.
  • Monitor for oral thrush: advise rinsing mouth after each use.
  • Use a spacer device: reduces oropharyngeal deposition.
  • Avoid abrupt discontinuation: taper to prevent rebound symptoms.
  • Review concomitant beta‑blocker therapy: may diminish bronchodilator effect.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Kantos can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: may antagonize bronchodilation.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can raise systemic corticosteroid levels.
  • Diuretics: may enhance hypokalaemia risk when combined with β2‑agonists.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: additive bronchodilator effect, monitor lung function.
  • Theophylline: possible increase in plasma concentrations.
  • Other inhaled corticosteroids: cumulative steroid exposure, assess total dose.

Frequently Asked Questions

Kantos is a prescription inhalation product that combines an inhaled corticosteroid with a long‑acting β2‑agonist. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults, helping to control inflammation and keep the airways open over the long term.

Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, suppressing the production of inflammatory mediators and reducing swelling and mucus formation. This anti‑inflammatory action helps to prevent asthma and COPD symptoms such as wheezing, coughing, and shortness of breath.

The dose of Kantos is individualized by the prescribing clinician based on the severity of the patient’s asthma or COPD, age, and response to therapy. The prescriber determines the number of inhalations per day and the total daily dose, which should be followed exactly as instructed.

Safety data for Kantos in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss the risks and benefits with their healthcare provider.

To request Kantos, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Kantos combines an inhaled corticosteroid (beclometasone) with a long‑acting β2‑agonist (formoterol) in a single inhaler, offering both anti‑inflammatory and bronchodilator effects. Compared with single‑component inhalers, this combination can simplify treatment regimens and improve adherence, while providing rapid onset bronchodilation similar to other LABA‑containing products.

Kantos should be stored at ambient temperature, below 25 °C. Keep the inhaler in its original packaging, protect it from moisture and direct sunlight, and ensure the mouthpiece remains clean to maintain dose accuracy and product stability.

Kantos is delivered by inhalation using a metered‑dose inhaler. The patient inhales a prescribed number of puffs, typically after exhaling fully, and holds their breath for a few seconds to allow the medication to reach the lower airways. Using a spacer can improve drug deposition and reduce oral side effects.

Serious risks include paradoxical bronchospasm, which can worsen breathing shortly after inhalation, severe allergic reactions such as anaphylaxis, and cardiac arrhythmias, especially in patients with underlying heart disease. Patients should seek immediate medical attention if they experience sudden breathlessness, swelling, rash, or irregular heartbeats.

Kantos is contraindicated in patients with a known hypersensitivity to beclometasone, formoterol, or any component of the inhaler. It should also be avoided in individuals who have experienced a severe paradoxical bronchospasm with previous use of inhaled β2‑agonists. Clinicians must assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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