Product image of Kantos Master (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous) supplied by GNH India

Kantos Master

Active Ingredient:
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Origin:
EU

Kantos Master (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous)

Formoterol fumarate and beclometasone dipropionate, the active ingredients in Kantos Master, are a combination inhaled corticosteroid and long‑acting β2‑agonist presented as an inhalation aerosol (metered‑dose inhaler) for inhalation use. They treat asthma and chronic obstructive pulmonary disease in adults and adolescents, providing anti‑inflammatory and bronchodilatory actions that help maintain airway patency and reduce exacerbations.

GNH India supplies Kantos Master as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Chiesi Farmaceutici S.P.A.

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Indications & Clinical Uses

  • Kantos Master combines an inhaled corticosteroid with a long‑acting β2‑agonist to manage obstructive airway diseases.
  • Asthma: improves symptom control and reduces the frequency of exacerbations.
  • COPD: enhances lung function and decreases dyspnea during daily activities.
  • Chronic bronchitis (COPD component): reduces cough and sputum production, improving quality of life.

How It Works

  • Formoterol fumarate binds to β2‑adrenergic receptors on airway smooth‑muscle cells, activating adenylate cyclase and raising cyclic AMP levels, which relaxes bronchial smooth muscle for prolonged bronchodilation. Beclometasone dipropionate penetrates airway cells and activates glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokine production, reduce edema, and limit mucus secretion, thereby providing anti‑inflammatory control of the airways.

Side Effects

Common Side Effects

  • Throat irritation or hoarseness.
  • Oral candidiasis (thrush).
  • Cough after inhalation.
  • Headache.

Serious or Rare Side Effects

  • Paradoxical bronchospasm.
  • Adrenal suppression with prolonged high‑dose use.
  • Severe allergic reactions, including anaphylaxis.
  • Cardiac arrhythmias or tachycardia.

Precautions & Warnings

Kantos Master should be used under medical supervision with attention to the following precautions.

  • Assess asthma or COPD control before initiating therapy.
  • Monitor for oral thrush and advise rinsing the mouth after each inhalation.
  • Avoid abrupt discontinuation; taper if used at high doses for a long period.
  • Use with caution in patients with cardiovascular disease.
  • Use with caution during pregnancy and lactation (category unknown).
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Kantos Master may interact with other medicines; relevant interactions are grouped below.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): increase systemic corticosteroid exposure.

Moderate Interactions (Monitor Closely)

  • Theophylline: may increase plasma concentrations; monitor levels.
  • Diuretics: monitor potassium as LABA can cause hypokalemia.
  • Ritonavir or other potent CYP3A4 inhibitors: may raise steroid levels, watch for systemic effects.

Frequently Asked Questions

Kantos Master is a prescription inhaler that combines formoterol fumarate and beclometasone dipropionate. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents, helping to control symptoms, reduce inflammation, and prevent exacerbations when used regularly as part of a comprehensive management plan.

Formoterol fumarate is a long‑acting β2‑adrenergic agonist. It binds to β2 receptors on airway smooth‑muscle cells, activating adenylate cyclase and increasing cyclic AMP levels, which leads to relaxation of the bronchial smooth muscle and prolonged bronchodilation for up to 12 hours, improving airflow in obstructive airway diseases.

Beclometasone dipropionate is an inhaled corticosteroid that penetrates airway cells and binds to glucocorticoid receptors. This interaction modulates gene transcription, suppressing the production of inflammatory cytokines, reducing airway edema, mucus secretion, and hyper‑responsiveness, thereby providing anti‑inflammatory control of asthma and COPD.

The specific dose and inhalation schedule for Kantos Master are determined by the prescribing healthcare professional based on the severity of the disease, patient age, and response to therapy. Patients should follow the prescriber’s instructions and the device’s dosing counter, and never adjust the dose without medical advice.

The safety of Kantos Master in pregnancy and lactation has not been fully established, and the product carries an unknown pregnancy category. Clinicians should weigh the potential benefits against possible risks, and pregnant or nursing women should discuss treatment options with their healthcare provider before using this inhaler.

To place an enquiry, visit the product page on gnhindia.com, enter the required quantity, and submit the request. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Kantos Master contains the same active ingredients—formoterol and beclometasone—as many other licensed combination inhalers, offering comparable efficacy in reducing symptoms and exacerbations. Differences may lie in device design, dose strength, and regional regulatory approvals; clinicians choose a product based on patient preference, inhaler technique, and local formularies.

Kantos Master should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and heat. Keep the inhaler away from direct sunlight and do not expose it to freezing conditions. Ensure the mouthpiece remains clean and replace the canister according to the manufacturer’s expiration date.

The patient should remove the cap, shake the inhaler gently, and exhale fully away from the device. Press down on the canister to release a metered dose while beginning a slow, steady inhalation, then hold the breath for about 10 seconds before exhaling. Rinse the mouth after each use to reduce the risk of oral thrush.

Kantos Master is contraindicated in patients with a known hypersensitivity to formoterol, beclometasone, or any excipients in the inhaler. It should also be avoided in individuals who have experienced a severe paradoxical bronchospasm with LABA therapy. Patients with uncontrolled cardiovascular disease should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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