Kartal (Nimesulide)

Nimesulide selectively blocks the cyclooxygenase‑2 (COX‑2) enzyme, decreasing the production of prostaglandins that mediate pain, fever, and inflammation. This targeted inhibition provides anti‑inflammatory and analgesic effects while sparing COX‑1 activity that protects the gastric lining.

The appropriate dosage of Kartal is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health. Physicians tailor the regimen to achieve optimal symptom control while minimizing potential risks.

Safety data for Nimesulide in pregnancy and lactation are limited, and the drug is generally avoided unless clearly needed. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternative therapies with their healthcare provider.

To request Kartal, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and import documentation.

Compared with non‑selective NSAIDs such as ibuprofen, Kartal’s selective COX‑2 inhibition may offer a lower risk of gastrointestinal irritation but still carries potential hepatic and renal concerns. Choice of therapy depends on individual risk factors, efficacy requirements, and physician judgment.

Kartal should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date.

Kartal is administered orally, usually with a full glass of water. It may be taken with or without food, but taking it with meals can help reduce possible gastrointestinal discomfort.

The most serious adverse events associated with Kartal include hepatotoxicity (liver injury), severe skin reactions such as Stevens‑Johnson syndrome, renal impairment, and anaphylactic allergic responses. Patients should seek immediate medical attention if they notice jaundice, rash, swelling, or breathing difficulties.

Kartal is contraindicated in individuals with known hypersensitivity to Nimesulide, other NSAIDs, or sulfonamide derivatives, as well as patients with active peptic ulcer disease, severe liver or kidney impairment, and those receiving anticoagulant therapy without close monitoring.