Product image of Kaspofungin Teva (Caspofungin) supplied by GNH India

Kaspofungin Teva

Active Ingredient:
Caspofungin
Origin:
EU

Kaspofungin Teva (Caspofungin)

Caspofungin, the active ingredient in Kaspofungin Teva, is an echinocandin presented as an intravenous solution for intravenous use. It treats serious fungal infections such as invasive candidiasis, esophageal candidiasis, and invasive aspergillosis in immunocompromised patients.

GNH India supplies Kaspofungin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Caspofungin is an echinocandin antifungal that targets the fungal cell wall.

  • Invasive candidiasis: provides effective therapy for bloodstream and deep‑tissue Candida infections.
  • Esophageal candidiasis: resolves mucosal infection in patients with esophageal involvement.
  • Invasive aspergillosis: used as treatment for severe Aspergillus infections in high‑risk patients.

How It Works

  • Caspofungin inhibits the enzyme β‑(1,3)‑D‑glucan synthase, preventing synthesis of β‑(1,3)‑D‑glucan, an essential structural component of the fungal cell wall. The resulting deficiency weakens the wall, leading to osmotic instability and fungal cell lysis without affecting human cells.

Side Effects

Caspofungin may cause a range of adverse reactions.

Common Side Effects

  • Fever: transient elevation of body temperature.
  • Chills: shaking sensations often accompanying infusion.
  • Nausea: mild to moderate upset stomach.
  • Elevated liver enzymes: transient increase in ALT/AST.

Serious or Rare Side Effects

  • Severe hypersensitivity reactions: including rash, bronchospasm, or anaphylaxis.
  • Hepatic failure: marked elevation of liver enzymes or jaundice.
  • Renal impairment: acute kidney injury or worsening of pre‑existing renal disease.

Precautions & Warnings

Caspofungin requires careful monitoring and specific handling precautions.

  • Monitor liver function: obtain baseline and periodic LFTs during therapy.
  • Assess renal function: evaluate creatinine clearance before and during treatment.
  • Evaluate for hypersensitivity: discontinue immediately if severe allergic reaction occurs.
  • Use caution in pre‑existing hepatic disease: adjust therapy based on clinical judgment.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Caspofungin can interact with several drug classes.

Major Interactions (Avoid)

  • Rifampin: strong CYP inducers may reduce caspofungin exposure.
  • Ketoconazole: potent CYP3A4 inhibitors may increase caspofungin levels.
  • Other echinocandins (e.g., micafungin): concurrent use may lead to additive toxicity.

Moderate Interactions (Monitor Closely)

  • Tacrolimus: immunosuppressants may require dose adjustment.
  • Aminoglycosides: nephrotoxic agents warrant renal function monitoring.
  • Azole antifungals: combined use may increase risk of hepatic adverse events.

Frequently Asked Questions

Kaspofungin Teva is indicated for the treatment of serious fungal infections, specifically invasive candidiasis, esophageal candidiasis, and invasive aspergillosis. It is used in patients with compromised immune systems where these infections can be life‑threatening.

Caspofungin belongs to the echinocandin class and inhibits the enzyme β‑(1,3)‑D‑glucan synthase. By blocking the synthesis of β‑(1,3)‑D‑glucan, an essential component of the fungal cell wall, the drug weakens the wall and leads to fungal cell lysis while sparing human cells.

The dosing regimen for Kaspofungin Teva is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and other clinical factors. The prescriber will set the appropriate dose and infusion schedule.

Safety data for caspofungin in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.

To order Kaspofungin Teva, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and import documentation.

Caspofungin is an echinocandin, offering a mechanism distinct from azole antifungals such as fluconazole. Compared with azoles, caspofungin has a lower risk of drug‑drug interactions and is effective against many azole‑resistant Candida species, but it requires intravenous administration and may be more costly.

Kaspofungin Teva must be stored refrigerated at 2‑8 °C. It should be kept in its original packaging, protected from light, and must not be frozen or shaken. Once prepared for infusion, it should be used within the time frame specified in the product labeling.

Kaspofungin Teva is administered as an intravenous infusion. The solution is reconstituted according to the manufacturer’s instructions and infused over a period typically ranging from 1 to 2 hours, depending on the clinical protocol and patient tolerance.

Serious risks include severe hypersensitivity reactions such as anaphylaxis, hepatic failure indicated by marked liver enzyme elevation or jaundice, and acute renal impairment. Patients should be monitored closely for signs of these events, and treatment should be discontinued if they occur.

Kaspofungin Teva is contraindicated in individuals with known hypersensitivity to caspofungin or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, as the drug may accumulate and increase toxicity risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.