Kastel (Ramipril, Rosuvastatin Calcium)

Ramipril inhibits the angiotensin‑converting enzyme, lowering vasoconstriction and aldosterone release, while Rosuvastatin blocks HMG‑CoA reductase, decreasing cholesterol synthesis and increasing LDL‑receptor activity. Together they address two major contributors to cardiovascular disease.

The appropriate dose of Kastel is determined by the prescribing clinician based on the patient’s blood pressure, lipid profile, renal function and overall risk factors. Dosage adjustments are made according to individual therapeutic response.

Kastel is generally not recommended for use during pregnancy because ACE inhibitors can harm the developing fetus. Safety during breastfeeding has not been established, so clinicians usually avoid prescribing it to nursing mothers unless the benefit outweighs the risk.

To place an order, submit an enquiry on the Kastel product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kastel combines a well‑studied ACE inhibitor (Ramipril) with a potent, long‑acting statin (Rosuvastatin). Compared with other combos, it offers a balance of blood‑pressure reduction and LDL‑cholesterol lowering, with a relatively low incidence of drug‑drug interactions when used according to prescribing guidelines.

Kastel tablets should be stored at ambient temperature, below 25 °C, in the original blister pack or container. Protect them from excess moisture, heat and direct sunlight to maintain potency.

Kastel is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew it.

Serious risks include angioedema, severe muscle breakdown (rhabdomyolysis), acute liver injury, hyperkalemia and acute renal failure. Patients should seek immediate medical attention if they experience swelling of the face or throat, dark urine, jaundice, or sudden loss of kidney function.

Kastel is contraindicated in individuals with known hypersensitivity to ACE inhibitors or statins, those with a history of angioedema related to ACE inhibition, severe hepatic impairment, or pregnant women. It should also be used with caution in patients with significant renal dysfunction.