Product image of Katarfluid Adulti (Carbocisteine) supplied by GNH India

Katarfluid Adulti

Active Ingredient:
Carbocisteine
Origin:
EU

Katarfluid Adulti (Carbocisteine)

Carbocisteine, the active ingredient in Katarfluid Adulti, is a mucolytic presented as an oral formulation for oral use. It reduces the viscosity of respiratory mucus and is employed in the management of chronic bronchitis, COPD, asthma with mucus hypersecretion, and productive upper respiratory infections in adult patients.

GNH India supplies Katarfluid Adulti as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for respiratory care products across global markets.

Manufacturer / TM Owner

Aurobindo Pharma (Italia) S.R.L.

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Indications & Clinical Uses

Carbocisteine is a mucolytic that acts on respiratory secretions to improve clearance in several chronic and acute conditions.

  • Chronic bronchitis: reduces mucus thickness and facilitates expectoration, helping to relieve cough and improve airflow.
  • Chronic obstructive pulmonary disease (COPD): thins bronchial secretions, aiding sputum clearance and reducing exacerbation frequency.
  • Asthma with mucus hypersecretion: decreases mucus viscosity, supporting better airway patency during attacks.
  • Upper respiratory tract infections with productive cough: promotes clearance of sputum, easing cough and speeding recovery.

How It Works

  • Carbocisteine modifies the structure of mucopolysaccharides in airway secretions, breaking disulfide bonds and decreasing polymer length. This reduces mucus viscosity and elasticity, enhancing ciliary transport and facilitating expectoration of bronchial secretions, thereby improving airway clearance.

Side Effects

Carbocisteine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhoea: loose stools, usually transient.
  • Abdominal pain: discomfort in the stomach region.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Hypersensitivity reactions: including anaphylaxis, requiring immediate medical attention.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Neutropenia or eosinophilia: abnormal blood counts.
  • Bronchospasm: worsening of breathing difficulty.

Precautions & Warnings

Before using Katarfluid Adulti, consider the following precautions.

  • Dose adjustment: assess renal function and adjust dose in patients with renal impairment.
  • Hypersensitivity: avoid in individuals with known allergy to carbocisteine or related compounds.
  • Peptic ulcer disease: use with caution as mucolytics may irritate the gastrointestinal tract.
  • Liver monitoring: periodic liver function tests are advisable during prolonged therapy.
  • Pregnancy and lactation: safety not established; consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Carbocisteine may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Cough suppressants (e.g., codeine): may counteract the expectorant effect of carbocisteine.
  • Anticholinergic agents: can diminish mucociliary clearance, reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Warfarin: carbocisteine may potentiate anticoagulant effect, requiring INR monitoring.
  • Theophylline: possible alteration of plasma concentrations, necessitating level checks.
  • ACE inhibitors: may increase cough frequency, potentially complicating assessment of therapeutic benefit.

Frequently Asked Questions

Katarfluid Adulti contains carbocisteine and is used as a mucolytic to thin and loosen mucus in the respiratory tract. It helps patients with chronic bronchitis, chronic obstructive pulmonary disease, asthma with mucus hypersecretion, and productive coughs from upper respiratory infections to clear secretions more effectively.

Carbocisteine reduces the viscosity of airway mucus by modifying the structure of mucopolysaccharides. It breaks disulfide bonds within the mucus polymers, decreasing their length and elasticity, which enhances ciliary movement and promotes easier expectoration of bronchial secretions.

The appropriate dose of Katarfluid Adulti is determined by the prescribing healthcare professional based on the patient’s condition, age, and renal function. Dosage regimens are individualized and should follow the prescriber’s instructions; no standard dose is provided here.

Safety of carbocisteine in pregnancy and lactation has not been definitively established. Healthcare providers should weigh potential benefits against possible risks and discuss them with the patient. Use only if clearly indicated and under medical supervision.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Katarfluid Adulti. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Carbocisteine differs from agents such as N‑acetylcysteine (NAC) by primarily altering mucopolysaccharide structure rather than acting as a thiol donor. Both reduce mucus viscosity, but carbocisteine may have a more favorable taste profile and fewer sulfur‑related side effects, while NAC possesses antioxidant properties useful in certain settings.

Katarfluid Adulti should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The medication is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the prescriber’s guidance on timing relative to meals to minimize gastrointestinal discomfort.

Serious adverse reactions, although rare, include hypersensitivity responses such as anaphylaxis, severe skin conditions like Stevens‑Johnson syndrome, hepatic dysfunction, neutropenia, eosinophilia, and bronchospasm. Patients should seek immediate medical attention if they experience any of these symptoms.

Katarfluid Adulti is contraindicated in individuals with a known hypersensitivity to carbocisteine or any of its excipients. Caution is also advised for patients with severe renal impairment, active peptic ulcer disease, or uncontrolled liver disease, and it should be avoided unless specifically prescribed in pregnancy or lactation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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