Product image of Katora (Sildenafil Citrate) supplied by GNH India

Katora

Active Ingredient:
Sildenafil Citrate
Origin:
EU

Katora (Sildenafil Citrate)

Sildenafil citrate, the active ingredient in Katora, is a phosphodiesterase type 5 (PDE5) inhibitor presented as an oral tablet for oral use. It is indicated for the treatment of erectile dysfunction and for pulmonary arterial hypertension in adult patients. It is marketed within the European Union and requires a prescription.

GNH India supplies Katora as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements across multiple markets, and is distributed through authorized channels.

Manufacturer / TM Owner

Neuraxpharm Bohemia S.R.O.

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Indications & Clinical Uses

Sildenafil citrate acts on the nitric‑oxide/cGMP pathway to improve vascular smooth‑muscle relaxation in specific conditions.

  • Erectile dysfunction: enhances ability to achieve and maintain an erection sufficient for sexual activity.
  • Pulmonary arterial hypertension: lowers pulmonary arterial pressure and improves exercise capacity in affected patients.

How It Works

  • Sildenafil citrate selectively inhibits phosphodiesterase type 5 enzymes, preventing the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels lead to relaxation of smooth muscle in the corpus cavernosum and pulmonary vasculature, facilitating increased blood flow and improved erectile function or reduced pulmonary arterial pressure.

Side Effects

Sildenafil citrate may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache
  • Flushing
  • Dyspepsia
  • Nasal congestion
  • Visual disturbances (e.g., blurred vision)

Serious or Rare Side Effects

  • Priapism (prolonged erection)
  • Sudden loss of vision (non‑arteritic anterior ischemic optic neuropathy)
  • Sudden loss of hearing
  • Cardiovascular events such as myocardial infarction or stroke

Precautions & Warnings

Before prescribing sildenafil citrate, clinicians should consider several safety factors.

  • Cardiovascular assessment: evaluate patients with underlying heart disease before use.
  • Nitrate therapy: contraindicated with nitrates or nitric‑oxide donors.
  • Blood pressure: use caution in uncontrolled hypertension or hypotension.
  • Renal/hepatic impairment: dose adjustment may be required in severe impairment.
  • Visual disorders: avoid in patients with retinitis pigmentosa or other retinal diseases.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Sildenafil citrate can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Nitrates (including nitroglycerin): concurrent use can cause severe hypotension.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase sildenafil exposure.

Moderate Interactions (Monitor Closely)

  • Alpha‑blockers: may enhance blood‑pressure‑lowering effects.
  • Antihypertensive agents: additive hypotensive effect possible.
  • CYP3A4 inducers (e.g., rifampin): may reduce sildenafil effectiveness.

Frequently Asked Questions

Katora contains sildenafil citrate and is prescribed to treat erectile dysfunction in men and to manage pulmonary arterial hypertension, a condition characterized by high blood pressure in the arteries of the lungs.

Sildenafil citrate selectively blocks the phosphodiesterase type 5 enzyme, which results in higher levels of cyclic GMP. This chemical relaxes smooth muscle in the penis and pulmonary vessels, improving blood flow and facilitating erection or reducing pulmonary pressure.

The dose of Katora is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Sildenafil citrate is not recommended for use during pregnancy or while breastfeeding because safety data are limited. Women who are pregnant, planning to become pregnant, or nursing should discuss alternative treatments with their healthcare provider.

To order Katora, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Katora (sildenafil) belongs to the PDE5 inhibitor class, similar to tadalafil and vardenafil. While all share the same mechanism, differences exist in duration of action, dosing frequency and specific side‑effect profiles, allowing clinicians to tailor therapy to individual patient needs.

Store Katora at temperatures below 25 °C, in its original packaging, and protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Katora is taken orally, usually with a glass of water. It may be taken with or without food, but a high‑fat meal can delay its onset of action. Patients should follow the timing instructions provided by their prescriber.

Serious risks include priapism (an erection lasting longer than four hours), sudden loss of vision or hearing, and cardiovascular events such as heart attack or stroke, especially in patients with pre‑existing heart disease. Immediate medical attention is required if any of these occur.

Katora should not be used by individuals taking nitrates, those with severe uncontrolled hypertension or hypotension, patients with known hypersensitivity to sildenafil, or men with certain retinal disorders such as retinitis pigmentosa. Contraindications should be confirmed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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