Product image of Kauliv (Teriparatide) supplied by GNH India

Kauliv

Active Ingredient:
Teriparatide
Origin:
EU

Kauliv (Teriparatide)

Teriparatide, the active ingredient in Kauliv, is a parathyroid hormone analog presented as a subcutaneous injection for subcutaneous use. It treats osteoporosis in postmenopausal women, men at high risk of fracture, and glucocorticoid‑induced osteoporosis.
GNH India supplies Kauliv as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Strides Pharma (Cyprus) Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Teriparatide is used as an anabolic therapy for bone loss conditions.

  • Osteoporosis in postmenopausal women: improves bone mineral density and reduces fracture risk.
  • Osteoporosis in men at high risk of fracture: stimulates bone formation to strengthen skeletal integrity.
  • Glucocorticoid‑induced osteoporosis: counteracts steroid‑related bone loss by enhancing osteoblast activity.

How It Works

  • Teriparatide binds to the parathyroid hormone 1 (PTH1) receptor on osteoblasts, activating intracellular cyclic AMP and protein kinase A pathways. This signaling cascade increases osteoblast proliferation and activity, promotes collagen synthesis, and enhances bone matrix formation, resulting in net bone gain when administered intermittently.

Side Effects

Teriparatide may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal discomfort.
  • Headache: transient cranial pain.
  • Dizziness: occasional light‑headedness.
  • Injection‑site reactions: redness, swelling, or pain at the administration site.
  • Hypercalcemia: mild elevation of serum calcium levels.

Serious or Rare Side Effects

  • Osteosarcoma: extremely rare malignant bone tumor reported in long‑term animal studies.
  • Severe hypercalcemia: marked increase in calcium requiring medical intervention.
  • Hypotension: significant drop in blood pressure after injection.
  • Anaphylactic reaction: acute allergic response with airway compromise.

Precautions & Warnings

Before initiating teriparatide therapy, consider the following precautions.

  • Hypercalcemia: avoid use in patients with elevated serum calcium.
  • Bone malignancy: contraindicated in individuals with active bone cancers or a history of osteosarcoma.
  • Prior radiation therapy: assess risk if the patient has received extensive skeletal radiation.
  • Renal impairment: monitor kidney function and calcium levels regularly.
  • Pregnancy and lactation: safety not established; use only if potential benefit justifies risk.

Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Teriparatide can interact with other agents that affect calcium metabolism.

Major Interactions (Avoid)

  • Calcium supplements or high‑dose vitamin D: may cause excessive hypercalcemia.
  • Other parathyroid hormone analogs: additive effects on calcium levels.
  • Bisphosphonates administered concurrently: may blunt anabolic response.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: increase calcium excretion, requiring monitoring of serum calcium.
  • Glucocorticoids: may reduce bone‑forming efficacy, necessitating dose adjustment.
  • Estrogen therapy: potential synergistic effect on bone turnover, monitor bone markers.

Frequently Asked Questions

Kauliv, containing teriparatide, is prescribed for osteoporosis in postmenopausal women, osteoporosis in men who have a high risk of fracture, and glucocorticoid‑induced osteoporosis. In each case the drug works to increase bone formation and improve skeletal strength, helping to lower the chance of fractures.

Teriparatide mimics the action of natural parathyroid hormone by binding to the PTH1 receptor on bone‑forming cells called osteoblasts. This activates signaling pathways that stimulate osteoblast proliferation, collagen production, and mineralization, leading to net bone gain when the drug is given intermittently.

The specific dose and treatment schedule for Kauliv are determined by the prescribing healthcare professional based on the patient’s clinical condition, weight, and response to therapy. Physicians follow approved labeling and clinical guidelines to set the appropriate regimen.

Safety of teriparatide in pregnancy or while nursing has not been established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified prescriber.

To place an order, submit an enquiry on the Kauliv product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and required import documentation.

Kauliv is a bone‑forming (anabolic) therapy, whereas many other osteoporosis drugs, such as bisphosphonates or denosumab, are anti‑resorptive agents that slow bone loss. Teriparatide directly stimulates new bone formation, offering a different mechanism that can be advantageous for patients with severe bone loss or who have not responded to anti‑resorptive therapy.

Kauliv should be stored at 2‑8 °C (refrigerated). Keep the product in its original packaging, protect it from light, and do not freeze or shake the vial. Maintaining the cold chain preserves the stability and efficacy of the teriparatide formulation.

Kauliv is given as a subcutaneous injection, typically into the thigh or abdomen. The injection is performed by a trained healthcare professional or, after proper instruction, by the patient themselves using a pre‑filled pen or syringe, following the dosing schedule prescribed by the clinician.

The most serious risks include the rare possibility of osteosarcoma, severe hypercalcemia, and serious allergic reactions such as anaphylaxis. Patients should be monitored regularly for signs of elevated calcium levels, unexplained bone pain, or any hypersensitivity symptoms, and therapy should be discontinued if these occur.

Kauliv is contraindicated in individuals with existing hypercalcemia, active bone malignancies (including osteosarcoma), a history of skeletal radiation therapy, or those who are pregnant or breastfeeding unless the prescriber determines the benefits outweigh the risks. Patients with severe renal impairment should also be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.