Product image of Keflex (Cefalexin Monohydrate) supplied by GNH India

Keflex

Active Ingredient:
Cefalexin Monohydrate
Origin:
EU

Keflex (Cefalexin Monohydrate)

Cefalexin Monohydrate, the active ingredient in Keflex, is a cephalosporin presented as an oral dosage form for systemic use. It is used to treat bacterial infections of the upper respiratory tract, skin and soft tissues, and the urinary system in adults and children as prescribed by a healthcare professional.

GNH India supplies Keflex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established quality‑assured manufacturing and distribution networks across Europe and other markets globally.

Manufacturer / TM Owner

Flynn Pharma Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Keflex (cefalexin monohydrate) is a cephalosporin antibiotic indicated for bacterial infections affecting specific organ systems.
  • Upper respiratory tract infections: treatment of acute bacterial sinusitis, pharyngitis, and tonsillitis caused by susceptible organisms.
  • Skin and soft tissue infections: therapy for cellulitis, impetigo, and wound infections due to susceptible bacteria.
  • Urinary tract infections: management of uncomplicated cystitis and pyelonephritis caused by susceptible strains.

How It Works

  • Cefalexin monohydrate inhibits bacterial cell wall synthesis by binding to penicillin‑binding proteins (PBPs) located on the bacterial membrane. This binding interferes with the cross‑linking of peptidoglycan strands, weakening the cell wall and leading to osmotic instability and bacterial cell death. The action is primarily bactericidal against susceptible Gram‑positive and some Gram‑negative organisms.

Side Effects

Adverse reactions may occur with cefalexin use. Monitoring and reporting are recommended.

Common Side Effects

  • Gastrointestinal upset: nausea, vomiting, abdominal pain.
  • Diarrhea: mild to moderate loose stools.
  • Skin rash: mild erythema or pruritus.
  • Headache.

Serious or Rare Side Effects

  • Clostridioides difficile‑associated colitis: severe diarrhea and colitis.
  • Hypersensitivity reactions: anaphylaxis, Stevens‑Johnson syndrome.
  • Hepatotoxicity: elevated liver enzymes or jaundice.

Precautions & Warnings

Before prescribing cefalexin, consider the following precautions.

  • Renal impairment: dose adjustment may be required.
  • Allergy history: avoid if known cephalosporin or penicillin allergy.
  • Pregnancy and lactation: use only if benefits outweigh risks.
  • Drug interactions: monitor concomitant use with anticoagulants or oral contraceptives.
  • Microbiological resistance: limit use to confirmed susceptible infections.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Cefalexin may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Probenecid: may increase cefalexin plasma concentrations, raising toxicity risk.
  • Anticoagulants (warfarin): may enhance anticoagulant effect, monitor INR closely.
  • Oral contraceptives: may reduce efficacy, advise alternative contraception.

Moderate Interactions (Monitor Closely)

  • Aminoglycosides: concurrent nephrotoxic potential, monitor renal function.
  • Diuretics: may affect renal clearance, observe renal parameters.
  • Allopurinol: may increase risk of rash.

Frequently Asked Questions

Keflex contains cefalexin monohydrate, a broad‑spectrum cephalosporin antibiotic. It is prescribed for bacterial infections of the upper respiratory tract such as sinusitis and pharyngitis, skin and soft‑tissue infections like cellulitis and impetigo, and uncomplicated urinary tract infections including cystitis and pyelonephritis.

Cefalexin monohydrate works by binding to bacterial penicillin‑binding proteins, which are essential for constructing the cell wall. This binding blocks the cross‑linking of peptidoglycan strands, weakening the wall and causing bacterial cell lysis. The result is a bactericidal effect against susceptible Gram‑positive and some Gram‑negative organisms.

The dose of Keflex is individualized by the prescribing healthcare professional based on the type and severity of infection, patient age, weight, renal function, and local susceptibility patterns. No universal dosing regimen is provided here; the prescriber will set the appropriate strength and frequency.

Safety data for cefalexin in pregnancy and lactation are limited. It is classified as a Category B drug in many regions, indicating no proven risk in animal studies but insufficient human data. Use only when the potential benefit justifies any possible risk to the fetus or infant, and discuss with a healthcare provider.

To order Keflex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Keflex belongs to the first‑generation cephalosporin class, offering strong activity against Gram‑positive organisms and modest Gram‑negative coverage. Compared with amoxicillin, another commonly used oral agent, cefalexin is less susceptible to beta‑lactamase degradation but may have a narrower spectrum against certain resistant strains. Choice depends on infection type, bacterial susceptibility and patient tolerance.

Store Keflex at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, direct sunlight and excessive heat. Do not store in bathrooms or near kitchen sinks. Ensure the packaging remains sealed until use to maintain product stability.

Keflex is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food may reduce gastrointestinal upset. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious adverse reactions, though rare, include Clostridioides difficile‑associated colitis, severe hypersensitivity such as anaphylaxis or Stevens‑Johnson syndrome, and hepatotoxicity presenting as jaundice or elevated liver enzymes. Patients should seek immediate medical attention if they develop persistent diarrhea, rash, swelling, or signs of liver dysfunction.

Keflex should be avoided in individuals with a documented allergy to cefalexin, other cephalosporins, or penicillins due to potential cross‑reactivity. It is also contraindicated in patients with a history of severe hypersensitivity reactions such as anaphylaxis, and in those with known severe renal impairment without appropriate dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.