Keforal (Cefalexin)

Cefalexin works by binding to penicillin‑binding proteins on the bacterial cell wall, blocking the transpeptidation step of peptidoglycan synthesis. This inhibition weakens the wall, causing osmotic lysis of susceptible bacteria. Its bactericidal activity depends on maintaining drug concentrations above the minimum inhibitory concentration for an adequate duration.

The dosage of cefalexin is individualized by the prescribing clinician according to the infection, severity, patient age, weight and renal function. Typical adult regimens range from 250 mg to 1 g every 6–12 hours, but the exact dose and schedule must follow the prescriber’s order.

Safety of cefalexin during pregnancy and lactation has not been definitively established. It should be used only when the potential benefit justifies any possible risk to the fetus or infant, and the prescribing physician should assess each case individually.

To request Keforal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with penicillin‑based agents, cefalexin offers a broader spectrum against Gram‑positive organisms and some Gram‑negative bacteria and is more resistant to β‑lactamase degradation. However, for infections caused by resistant strains, newer cephalosporins or carbapenems may be preferred.

Keforal tablets should be stored at ambient temperature below 25 °C, in the original container, protected from moisture and direct light. Do not store in areas of high humidity or extreme heat, and keep the medication out of reach of children.

Keforal is taken orally, usually with a glass of water. It may be taken with or without food; taking it with food can help reduce gastrointestinal upset. The exact dosing interval (e.g., every 6 or 12 hours) is determined by the prescriber.

Serious adverse reactions include severe allergic responses such as anaphylaxis or Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, hematologic abnormalities like neutropenia, and hepatic or renal dysfunction. Immediate medical attention is required if a patient develops rash, fever, jaundice or persistent diarrhea.

Keforal should be avoided in individuals with a known hypersensitivity to cefalexin, other cephalosporins or penicillins. It is contraindicated in patients with severe renal impairment unless the dose is adjusted, and should be used with caution in those with a history of gastrointestinal disease or colitis.