Product image of Kelis Gola (Ketoprofen Lysine) supplied by GNH India

Kelis Gola

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Kelis Gola (Ketoprofen Lysine)

Ketoprofen, the active ingredient in Kelis Gola, is a nonsteroidal anti‑inflammatory drug presented as a formulation for oromucosal use. It treats pain and inflammation in adults. GNH India supplies Kelis Gola as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Epifarma S.R.L.

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Indications & Clinical Uses

Ketoprofen, a nonsteroidal anti‑inflammatory drug, is used to manage pain and inflammation in musculoskeletal conditions.

  • Rheumatoid arthritis: reduces joint pain and swelling.
  • Osteoarthritis: alleviates chronic joint discomfort.
  • Acute musculoskeletal injury: provides short‑term pain relief.

How It Works

  • Ketoprofen lysine reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever responses at the site of tissue injury.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal upset (nausea, dyspepsia).
  • Headache.
  • Dizziness.
  • Mild skin rash.
  • Increased blood pressure.
  • Transient renal function changes.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Anaphylactic or severe hypersensitivity reactions.
  • Significant renal impairment.
  • Hepatic dysfunction.
  • Cardiovascular events such as myocardial infarction.

Precautions & Warnings

When using Ketoprofen, consider the following safety measures.

  • Assess renal function: avoid or adjust use in patients with severe renal impairment.
  • Monitor hepatic function: contraindicated in severe liver disease.
  • Avoid in patients with known hypersensitivity to NSAIDs or aspirin.
  • Use with caution in the elderly: increased risk of gastrointestinal complications.
  • Avoid concomitant use with anticoagulants or other drugs that increase bleeding risk.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Ketoprofen can interact with several medication classes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function when combined.
  • Diuretics: potential for renal impairment.
  • Lithium: ketoprofen may raise lithium serum levels.

Frequently Asked Questions

Kelis Gola contains ketoprofen lysine, an NSAID that is prescribed to relieve pain, reduce inflammation, and improve mobility in conditions such as rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries.

Ketoprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, pain signaling, and fever at the site of injury.

The specific dose of Kelis Gola is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen is generally not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. It is also excreted in breast milk, so use while breastfeeding should be discussed with a qualified healthcare provider.

To request Kelis Gola, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Kelis Gola (ketoprofen) offers potent anti‑inflammatory and analgesic effects similar to ibuprofen and naproxen, but it may have a slightly higher risk of gastrointestinal irritation. Choice of NSAID depends on individual patient factors, tolerability, and the prescribing clinician’s assessment.

Kelis Gola should be stored at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain product stability.

Kelis Gola is intended for oromucosal administration. The tablet or formulation is placed in the mouth and allowed to dissolve, ensuring direct absorption through the oral mucosa as directed by the prescriber.

Serious risks include gastrointestinal ulceration or bleeding, severe skin reactions such as Stevens‑Johnson syndrome, anaphylaxis, significant renal impairment, and cardiovascular events like myocardial infarction. Patients should be monitored for these adverse events, especially with long‑term use.

Kelis Gola should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, and patients in the third trimester of pregnancy. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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