Product image of Kemic (Dexketoprofen) supplied by GNH India

Kemic

Active Ingredient:
Dexketoprofen
Origin:
EU

Kemic (Dexketoprofen)

Dexketoprofen, the active ingredient in Kemic, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It is indicated for the relief of mild to moderate pain, including musculoskeletal, post‑operative and dental discomfort, in adult patients.

GNH India supplies Kemic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

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Indications & Clinical Uses

Dexketoprofen acts as an NSAID to reduce pain and inflammation in several clinical settings.

  • Mild to moderate pain: provides analgesia for everyday aches and short‑term discomfort.
  • Musculoskeletal pain: alleviates pain associated with strains, sprains and inflammatory joint conditions.
  • Post‑operative pain: helps control pain after surgical procedures.
  • Dental pain: reduces pain and swelling following dental interventions.

How It Works

  • Dexketoprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which decreases the synthesis of prostaglandins involved in pain, inflammation and fever. This reduction in prostaglandin levels leads to the observed analgesic, anti‑inflammatory, and antipyretic actions of the drug.

Side Effects

Dexketoprofen may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Dyspepsia or stomach discomfort.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.
  • Diarrhoea.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reactions such as angioedema or anaphylaxis.
  • Hepatic dysfunction.
  • Renal impairment or acute kidney injury.
  • Cardiovascular events like myocardial infarction or stroke.
  • Blood dyscrasias including thrombocytopenia.

Precautions & Warnings

When using Dexketoprofen, consider the following safety measures.

  • Gastrointestinal risk: avoid use in patients with active ulcers or a history of GI bleeding.
  • Cardiovascular caution: use cautiously in individuals with established heart disease or risk factors.
  • Renal monitoring: assess kidney function in patients with pre‑existing renal impairment.
  • Drug interactions: review concomitant medications, especially other NSAIDs or anticoagulants.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Dexketoprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Other NSAIDs or aspirin: increased risk of gastrointestinal bleeding.
  • Anticoagulants (e.g., warfarin): potentiation of anticoagulant effect leading to hemorrhage.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive efficacy.
  • Diuretics: risk of renal function decline.
  • Lithium: NSAIDs may raise lithium serum levels.
  • Methotrexate: reduced clearance may increase toxicity.
  • Corticosteroids: additive gastrointestinal ulcer risk.

Frequently Asked Questions

Kemic, containing dexketoprofen, is prescribed for mild to moderate pain such as musculoskeletal aches, post‑operative discomfort, and dental pain. It helps reduce inflammation and provides analgesia in adult patients who need short‑term relief.

Dexketoprofen works by reversibly inhibiting the COX‑1 and COX‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever, resulting in the drug’s analgesic and anti‑inflammatory effects.

The appropriate dose of Kemic is determined by the prescribing healthcare professional based on the patient’s condition, age, and overall health. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety of dexketoprofen in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To request Kemic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Dexketoprofen is the S‑enantiomer of ketoprofen, offering rapid onset of analgesia with a potentially lower gastrointestinal risk profile compared with some traditional NSAIDs. However, overall safety and efficacy depend on individual patient factors and should be evaluated by a clinician.

Kemic should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and store it out of reach of children.

Kemic is taken orally, usually with a glass of water. It may be taken with or without food, but taking it with food can help reduce possible stomach irritation. Follow the prescriber’s instructions for timing and frequency.

Serious risks include gastrointestinal ulceration or bleeding, severe allergic reactions such as anaphylaxis, renal impairment, and cardiovascular events like myocardial infarction or stroke. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, vomiting blood, or sudden shortness of breath.

Kemic should be avoided in patients with known hypersensitivity to dexketoprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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