Product image of Kendix (Aciclovir) supplied by GNH India

Kendix

Active Ingredient:
Aciclovir
Origin:
EU

Kendix (Aciclovir)

Aciclovir, the active ingredient in Kendix, is an antiviral presented as a topical preparation for cutaneous use. It is used to treat herpes‑related skin infections by inhibiting viral replication in the affected area.
GNH India supplies Kendix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

Kendix, an anti‑herpetic antiviral, is applied to the skin to manage infections caused by herpes viruses.

  • Herpes labialis (cold sores): shortens lesion duration and reduces pain.
  • Genital herpes (topical treatment): alleviates symptoms and promotes healing of external lesions.
  • Herpes zoster (localized lesions): limits viral replication in the affected dermatome, helping to control rash progression.

How It Works

  • Aciclovir is a nucleoside analogue that, after phosphorylation by viral thymidine kinase, competitively inhibits viral DNA polymerase. This blocks the elongation of viral DNA strands, preventing replication of herpes simplex and varicella‑zoster viruses in infected cutaneous cells.

Side Effects

Topical aciclovir may cause local reactions, most of which are mild and reversible.

Common Side Effects

  • Mild skin irritation
  • Itching at the application site
  • Redness or erythema
  • Burning sensation
  • Dryness of the treated area

Serious or Rare Side Effects

  • Allergic contact dermatitis
  • Severe skin reaction such as Stevens‑Johnson syndrome
  • Systemic absorption leading to renal toxicity (rare)
  • Ocular involvement if applied near the eyes
  • Extensive ulceration or necrosis of skin.

Precautions & Warnings

When using Kendix, consider the following safety measures.

  • Avoid application on extensive broken skin: limit use to small, intact lesions.
  • Do not apply near eyes or mucous membranes: risk of irritation.
  • Keep out of reach of children: accidental ingestion can occur.
  • Consult a physician if renal impairment is present: systemic absorption may increase.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Topical aciclovir can interact with other agents applied to the same area or systemic drugs that affect renal function.

Major Interactions (Avoid)

  • Concurrent systemic aciclovir: risk of cumulative toxicity.
  • Co‑administration with nephrotoxic drugs (e.g., aminoglycosides): may increase renal risk.
  • Use with probenecid: can raise systemic aciclovir levels.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask local irritation.
  • Other antiviral creams: additive antiviral effect, monitor for skin reactions.
  • Immunosuppressants: may affect healing time, observe lesion response.

Frequently Asked Questions

Kendix is a topical antiviral medication indicated for the treatment of herpes labialis (cold sores), genital herpes lesions, and localized herpes zoster (shingles) skin eruptions. It works by reducing viral replication in the skin, helping to shorten lesion duration and relieve associated discomfort.

Aciclovir is a nucleoside analogue that, once phosphorylated by viral enzymes, inhibits the viral DNA polymerase. This blocks the synthesis of viral DNA, preventing the herpes virus from multiplying in the infected skin cells and allowing the immune system to clear the infection more effectively.

The dosage of Kendix is determined by the prescribing healthcare professional based on the specific indication, lesion size, and patient factors. The prescriber will provide instructions on the amount to apply, frequency, and duration of treatment.

Safety data for topical aciclovir in pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against any unknown risks. Women who are pregnant or breastfeeding should discuss the use of Kendix with their physician before starting treatment.

To order Kendix, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Kendix contains aciclovir, a well‑established antiviral with a long safety record. Compared with newer agents such as penciclovir or docosanol, aciclovir offers a broad spectrum against HSV‑1, HSV‑2 and VZV, and is often preferred for its proven efficacy in topical formulations.

Kendix should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability.

Kendix is applied directly to the affected skin area. Clean and dry the lesion, then spread a thin layer of the cream or ointment as directed by the prescriber, usually several times daily for the prescribed duration.

Serious but rare risks include allergic contact dermatitis, severe skin reactions such as Stevens‑Johnson syndrome, and, in exceptional cases, systemic absorption leading to renal toxicity. Patients should discontinue use and seek medical attention if they notice severe rash, swelling, or kidney‑related symptoms.

Kendix should not be used on extensive broken skin, near the eyes or mucous membranes, or by individuals with known hypersensitivity to aciclovir or any excipients in the formulation. Patients with severe renal impairment should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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